1,799 results match your criteria: "University of Trás-of-Montes and Alto Douro[Affiliation]"

Sensory Changes Following the Lateral Nasal Wall Surgery: A Systematic Review.

Cureus

December 2024

Otolaryngology, Local Health Unit of Trás-os-Montes and Alto Douro (ULSTMAD), Vila Real, PRT.

The objective of this study was to analyze the sensory changes reported by patients after lateral nasal wall surgery and to assess the prevalence and severity of sensory disturbances, the factors that influence their occurrence, and their impact on patients' quality of life. The methodology adopted in this study was PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analysis), as well as the PICO (Population, Intervention, Comparison, Outcomes) strategy, which assisted in the development of the study's objectives. Based on the inclusion and exclusion criteria, among all the articles retrieved in the searched databases (PubMed and Google Scholar), we selected 15 articles, considered to be pertinent and relevant to the present investigation.

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Empowering the Sports Scientist with Artificial Intelligence in Training, Performance, and Health Management.

Sensors (Basel)

December 2024

Research Center in Sports Sciences, Health Sciences and Human Development, CIDESD, CreativeLab Research Community, 5000-801 Vila Real, Portugal.

Artificial Intelligence (AI) is transforming the field of sports science by providing unprecedented insights and tools that enhance training, performance, and health management. This work examines how AI is advancing the role of sports scientists, particularly in team sports environments, by improving training load management, sports performance, and player well-being. It explores key dimensions such as load optimization, injury prevention and return-to-play, sports performance, talent identification and scouting, off-training behavior, sleep quality, and menstrual cycle management.

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Let-7b, miR-29b, and miR-125b as Potential Biomarkers for Differentiating Canine Mammary Carcinoma Histological Types.

Animals (Basel)

December 2024

Molecular Oncology and Viral Pathology Group, Research Center of IPO Porto (CI-IPOP)/RISE@CI-IPOP (Health Research Network), Portuguese Oncology Institute of Porto (IPO Porto)/Porto Comprehensive Cancer Center (Porto.CCC), 4200-072 Porto, Portugal.

Epigenetics is the study of changes in organisms that result from modifications in gene expression rather than alterations in the genetic code itself [...

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Chronic pruritus, or persistent itching, is a debilitating condition that severely impacts quality of life, especially in palliative care settings. Traditional treatments often fail to provide adequate relief or are associated with significant side effects, prompting interest in alternative therapies. This review investigates the antipruritic potential of eight medicinal plants: chamomile (), aloe vera (), calendula (), curcumin (), lavender (), licorice (), peppermint (), and evening primrose ().

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Permeable asphalt pavement (PAP) is an efficient solution to stormwater management, allowing water to infiltrate through its layers. This reduces surface runoff and mitigates urban flooding risks. In addition to these hydrological benefits, PAP enhances water quality by filtering pollutants such as organic and inorganic materials and microplastics.

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Analysis of Growth Models in Galician × Nelore Crossbred Cattle in the First Year of Life.

Animals (Basel)

December 2024

CISAS-Center for Research in Agrifood Systems and Sustainability, Instituto Politécnico de Viana do Castelo, Rua da Escola Industrial e Comercial Nun'Alvares 34, 4900-347 Viana do Castelo, Portugal.

The veal niche market is gaining momentum in Brazil. Locally known as 'Vitelão', veal refers to the meat from calves slaughtered up to 12 months of age. In this study, we assessed the Galician Blond × Nelore cross as a candidate to produce veal.

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This study aimed to investigate the impact of different offensive-reward-related rules on the physical performance, perceived exertion and enjoyment of young basketball players during small-sided games (SSG). Eighteen youth male players (age: 13.3±0.

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Introduction Chronic rhinosinusitis (CRS) presents with different clinical patterns with variable responses to treatment. Clear criteria for specifying disease severity and assessing symptom control are lacking in the current literature. We aimed to perform a cross-cultural adaptation of the chronic rhinosinusitis patient-reported outcomes (CRS-PRO), creating a Portuguese version to use as a routine questionnaire in the evaluation of patients with CRS.

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Mammary Cancer Models: An Overview from the Past to the Future.

In Vivo

December 2024

Centre for the Research and Technology of Agro-Environmental and Biological Sciences (CITAB), University of Trás-os-Montes and Alto Douro (UTAD), Vila Real, Portugal.

Breast cancer research heavily relies on diverse model systems to comprehend disease progression, develop novel diagnostics, and evaluate new therapeutic strategies. This review offers a comprehensive overview of mammary cancer models, covering both ex vivo and in vivo approaches. We delve into established techniques, such as cell culture and explore cutting-edge advancements, like tumor-on-a-chip and bioprinting.

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 - a large-scale dataset of 3D medical shapes for computer vision.

Biomed Tech (Berl)

December 2024

Institute for Artificial Intelligence in Medicine (IKIM), University Hospital Essen (AöR), Essen, Germany.

Objectives: The shape is commonly used to describe the objects. State-of-the-art algorithms in medical imaging are predominantly diverging from computer vision, where voxel grids, meshes, point clouds, and implicit surface models are used. This is seen from the growing popularity of ShapeNet (51,300 models) and Princeton ModelNet (127,915 models).

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Cutaneous squamous cell carcinoma (CSCC) in dogs is a locally invasive tumor that typically occurs in areas of poorly pigmented skin due to sun exposure. Identifying new biomarkers, such as syndecan-1 (CD138) and E-cadherin, is fundamental for tumor diagnosis and prognosis. Dysregulation of syndecan-1, expressed in epithelial tissue, fibroblasts, and plasma cells, is associated with poor prognosis in several types of cancer.

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Canine hip dysplasia (CHD) screening relies on accurate positioning in the ventrodorsal hip extended (VDHE) view, as even mild pelvic rotation can affect CHD scoring and impact breeding decisions. This study aimed to assess the association between pelvic rotation and asymmetry in obturator foramina areas (AOFAs) and to develop a computer vision model for automated AOFA measurement. In the first part, 203 radiographs were analyzed to examine the relationship between pelvic rotation, assessed through asymmetry in iliac wing and obturator foramina widths (AOFWs), and AOFAs.

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Aflatoxin Contamination of Various Staple Foods from Angola and Mozambique.

Toxins (Basel)

November 2024

CIMO, LA SusTEC, Instituto Politécnico de Bragança, Campus de Santa Apolónia, 5300-253 Bragança, Portugal.

Aflatoxins constitute a significant risk in staple foods produced in African countries. This research aimed to analyze the total aflatoxin (AFT) contamination of various staple foods in Angola and Mozambique. A total of 233 samples of corn, peanuts, beans, rice, and cassava flour collected from farmers or local markets from the province of Cuanza Sul, Angola, and the provinces of Gaza and Inhambane, South Mozambique, were analyzed for the presence of AFT using the lateral flow strip method via AgraStrip Pro WATEX (Romer).

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Chemical characterization and antioxidant potential of Arthrospira sp., Thalassiosira sp., and Raphidonema sp.

Food Chem

December 2024

Centre of Molecular and Environmental Biology (CBMA), Department of Biology, Campus of Gualtar, University of Minho, 4710-057 Braga, Portugal; IBS, Institute of Science and Innovation for Bio-Sustainability, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal. Electronic address:

Microalgae are emerging as valuable sources of bioactive compounds. This study evaluates hexane extracts from Thalassiosira sp. and Raphidonema sp.

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This study aimed to examine the effects of two different complex training protocols on physical performance in highly-trained youth basketball players. Fourteen adolescent players participated in twice-weekly sessions over eight weeks, following either the Drop Jump protocol (n = 7) or the Tic-tac protocol (n = 7), performing 1-3 sets of 8-9 exercises. Physical performance was assessed before and after the intervention using jumping tests (CMJ, squat, 10-5 hop jumps), change-of-direction speed (5-10-5), sprinting (0-20 meters), and muscular strength (isometric midthigh pull) tests.

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The aim of this study was to examine the influence of three warm-up protocols, with and without post-activation performance enhancement (PAPE), on sprint and vertical jump performance in female athletes. Twenty-five university futsal athletes were randomly assigned to three protocols: i) Traditional Warm-Up (TWU), involving cardiovascular, coordination exercises, and dynamic stretching; ii) Drop Jump Warm-Up (DJWU), consisting of drop jumps from heights of 30 and 40 cm; and iii) Maximum Isometric Warm-Up (MIWU), with high-intensity isometric contractions held for 10 seconds in a squat position at approximately 130-135 degrees of knee flexion. Tests included the countermovement vertical jump (CMVJ) and a 20-meter sprint (S20).

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In patients with aspirin-exacerbated respiratory disease (AERD), there is disparate regulation of prostaglandin E2 (PGE) and prostaglandin D (PGD). Both prostanoids are synthesised by cyclooxygenase 1 (COX-1) and cyclooxygenase 2 (COX-2). However, while the basal synthesis of PGE tends to decrease, that of PGD increases in patients with AERD.

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Behavioral, metabolic, and biochemical alterations caused by an acute stress event in a zebrafish larvae model.

Fish Physiol Biochem

February 2025

Centre for the Research and Technology of Agro-Environment and Biological Sciences (CITAB), University of Trás-Os-Montes and Alto Douro (UTAD), Vila Real, Portugal.

Animal welfare is a growing concern in aquaculture practices. Stress induced by handling or transportation can lead to negative impacts on the sector. Zebrafish has raised as an important aquaculture model, but still with few focus on its stress response in early life stages.

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Early developmental effects of propofol exposure in different stages of zebrafish embryos.

Toxicol Lett

January 2025

i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, 4200-135 Porto, Portugal; Laboratory Animal Science, IBMC - Instituto de Biologia Molecular e Celular, Universidade do Porto, 4200-135 Porto, Portugal.

The mechanism of action of propofol, a common intravenous anaesthetic, in early life stages is not well understood with contradictory studies showing neurotoxic and neurogenic effects in the developing brain. Zebrafish early life stages have been established as an alternative model for animal experimentation with propofol toxicological effects reported following chronic exposure. Yet, the acute exposure to other anaesthetics has been shown to induce early life stage-dependent toxicological outcomes.

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Synthetic pesticides are known for their toxic effects on non-target aquatic organisms. However, little is known about their effects when present in mixtures, which are closer to realistic exposure scenarios. Therefore, this study evaluates the toxicity of pesticides such as diuron, atrazine and glyphosate, individually and in combination, in zebrafish embryos, investigating their mechanisms of oxidative stress.

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Cumulus cell DNA damage linked to fertilization success in females with an ovulatory dysfunction phenotype.

Front Cell Dev Biol

November 2024

Molecular Genetics Laboratory, Laboratory Genetics Service, Genetics and Pathology Clinic, Centro Hospitalar Universitário de Santo António, Unidade Local de Saúde de Santo António, Porto, Portugal.

Article Synopsis
  • Intracytoplasmic sperm injection (ICSI) relies on the health of both oocytes and cumulus cells; this study investigates the role of DNA damage in these cumulus cells as it relates to fertilization success.
  • Using the alkaline comet assay, researchers compared DNA damage levels in cumulus cells and whole blood from potentially fertile and infertile females, finding significant differences.
  • Results indicate that higher DNA damage in cumulus cells correlates with lower fertilization success in females with ovulatory dysfunction, suggesting DNA damage could be a useful biomarker for predicting oocyte competence.
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spp. are a genus of Gram-negative, opportunistic bacteria frequently found in the flora of the mucosal membranes of healthy animals and humans, and in the environment. Species of this group can cause serious infections (meningitis, sepsis, bacteraemia, urinary tract infections, liver damage) and possible death in immunocompromised organisms (and even in immunocompetent ones in the case of hypervirulent ) that are exposed to them.

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This study investigates the impact of organic (OF) and conventional farming (CF) on soil fungal communities in banana monoculture plantations on Madeira Island. We hypothesized that OF promotes beneficial fungal groups over harmful ones, sustaining soil health. Soil samples were collected from six plantations (three OF and three CF) for ITS amplicon sequencing to assess fungal diversity.

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Biomimetic Model of Canine Periodontal Ligament.

Int J Mol Sci

November 2024

BoneLab-Laboratory for Bone Metabolism and Regeneration, Faculty of Dental Medicine, U.Porto, 4200-393 Porto, Portugal.

Periodontal disease affects about 80% of dogs, highlighting the importance of addressing periodontitis in veterinary dental care. The periodontal ligament (PDL) is a key structure holding the potential to regenerate the entire periodontal complex. This work presents an in vitro model of canine PDL-derived cell cultures that mimic the PDL's regenerative capacity for both mineralised and soft tissues.

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