3 results match your criteria: "University of Toronto and the Centre for Addiction and Mental Health[Affiliation]"
Life changes among homeless persons with mental illness: a longitudinal study of housing first and usual treatment.
Psychiatr Serv
June 2015
Dr. Nelson, Dr. Macnaughton, and Mr. MacLeod are with the Department of Psychology, Wilfrid Laurier University, Waterloo, Ontario, Canada (e-mail: Dr. Patterson is with the Faculty of Health Sciences, Simon Fraser University, Burnaby, British Columbia, Canada. Dr. Kirst is with the Institute of Health Policy, Management and Evaluation and Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada. Ms. Isaak is with the Department of Psychiatry, University of Manitoba, Winnipeg, Manitoba, Canada. Dr. Nolin is with the Département d'Éducation, University of Moncton, Shippagan, New Brunswick, Canada. Dr. McAll is with the Département de Sociologie, Université de Montréal, Montréal, Quebec, Canada. Dr. Stergiopoulos is with the Department of Psychiatry, St. Michael's Hospital, University of Toronto, Toronto, Ontario. Dr. Townley is with the Department of Psychology, Portland State University, Portland, Oregon. Dr. Piat is with the Department of Psychiatry and the Department of Social Work, McGill University, Douglas Mental Health Institute, Montreal, Quebec. Dr. Goering is with the Department of Psychiatry, University of Toronto and the Centre for Addiction and Mental Health, Toronto, Ontario.
Objective: This study compared the life changes of homeless people with mental illness participating in Housing First or treatment as usual and examined factors related to various changes.
Methods: Semistructured narrative interviews were conducted with 219 participants in five Canadian cities at baseline; 197 were interviewed again at 18 months after random assignment to Housing First (N=119) or treatment as usual (N=78). Interviews were coded across 13 life domains, and each participant was categorized as reporting positive, mixed-neutral, or negative changes.
The effects of aging on insight into illness in schizophrenia: a review.
Int J Geriatr Psychiatry
November 2014
University of Toronto and the Centre for Addiction and Mental Health, Toronto, ON, Canada.
Objectives: Impaired insight into illness is a prevalent feature of schizophrenia, which negatively influences treatment adherence and clinical outcomes. Little is known about the effects of aging on insight impairment. We aimed to review the available research literature on the effects of aging on insight into illness in schizophrenia, in relation to positive, negative, and cognitive symptoms.
View Article and Find Full Text PDFOligomerization of mu- and delta-opioid receptors. Generation of novel functional properties.
J Biol Chem
August 2000
Departments of Pharmacology and Medicine, University of Toronto and the Centre for Addiction and Mental Health, Toronto, Ontario M5S 1A8, Canada.
The existence of dimers and oligomers for many G protein-coupled receptors has been described by us and others. Since many G protein-coupled receptor subtypes are highly homologous to each other, we examined whether closely related receptors may interact with each other directly and thus have the potential to create novel signaling units. Using mu- and delta-opioid receptors, we show that each receptor expressed individually was pharmacologically distinct and could be visualized following electrophoresis as monomers, homodimers, homotetramers, and higher molecular mass oligomers.
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