645 results match your criteria: "University of Texas at Austin- Dell Medical School[Affiliation]"

Abortion is a frequent topic of policy debate in America and a central issue in politics since the Dobbs v Jackson Women's Health Supreme Court decision. A number of states have completely or nearly completely banned abortion and criminalized health care providers. People seeking abortion care are turning to alternatives outside the formal health care system or traveling to states that have preserved access.

View Article and Find Full Text PDF
Article Synopsis
  • - Cronkhite-Canada Syndrome (CCS) is a rare polyposis condition affecting 1 in a million, with unknown causes and treatments due to its scarcity and lack of research models.
  • - Researchers created human intestinal organoids (HIOs) from two CCS patients, finding that these organoids are highly proliferative and produce more serotonin (5HT), which is linked to the growth of intestinal tissue.
  • - The study highlights how organoid cultures can help understand CCS's disease mechanisms and could lead to personalized treatments, demonstrating the impact of intestinal hormones on epithelial cell growth.
View Article and Find Full Text PDF

Background: Multiple challenges impede interprofessional teamwork and the provision of high-quality care to hospitalized patients.

Objective: To evaluate the effect of interventions to redesign hospital care delivery on teamwork and patient outcomes.

Design: Pragmatic controlled trial.

View Article and Find Full Text PDF

Pediatric diabetes: management of acute complications in the emergency department.

Pediatr Emerg Med Pract

November 2023

Associate Professor of Pediatrics, Department of Pediatrics, University of Texas at Austin Dell Medical School, Austin, TX; US Acute Care Solutions, Canton, OH.

Children with diabetes mellitus are at high risk for acute life-threatening complications of their chronic disease. Identification and management of these emergencies can be complex and challenging. This issue provides guidance for recognizing pediatric patients with new-onset diabetes as well as diabetic crises in established patients.

View Article and Find Full Text PDF

Introduction: Use of telehealth for outpatient endocrine care remains common since onset of the COVID-19 pandemic, though the context for its use has matured. We aimed to describe the variation in telehealth use for outpatient endocrine visits under these "new normal" conditions and examine the patient, clinician-, and organization-level factors predicting use.

Methods: Retrospective cross-sectional study using data from the U.

View Article and Find Full Text PDF

Health Care Disparities in Patients Undergoing Hysterectomy for Benign Indications: A Systematic Review.

Obstet Gynecol

November 2023

Department of Obstetrics and Gynecology, David Geffen School of Medicine at UCLA, Los Angeles, California; the Division of Urogynecology & Reconstructive Pelvic Surgery, Departments of Obstetrics and Gynecology and Urology, New York Medical College, Valhalla, New York; the Center for Evidence Synthesis in Health, Brown University School of Public Health, Providence, Rhode Island; the Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics & Gynecology, Wayne State University School of Medicine, Detroit, Michigan; the Division of Urogynecology & Reconstructive Pelvic Surgery, Department of Obstetrics and Gynecology, Yale School of Medicine, New Haven, Connecticut; the Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics & Gynecology, Howard University College of Medicine, Washington, DC; the Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics & Gynecology, University of Florida Health, Jacksonville, Florida; Occom Health, Newton, Massachusetts; the Division of Urogynecology & Reconstructive Pelvic Surgery, Cooper Health University, Cooper Medical School at Rowan University, Camden, New Jersey; the Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics & Gynecology, University of Louisville Health, Louisville, Kentucky; the Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics & Gynecology, University of Texas at Austin Dell Medical School, Austin, and the Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics & Gynecology, Baylor College of Medicine, the Division of Urogynecology, Department of Obstetrics & Gynecology, Houston Methodist Hospital, Houston, Texas; and the Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics & Gynecology, University of New Mexico, Albuquerque, New Mexico.

Objective: To explore how markers of health care disparity are associated with access to care and outcomes among patients seeking and undergoing hysterectomy for benign indications.

Data Sources: PubMed, EMBASE, and ClinicalTrials.gov were searched through January 23, 2022.

View Article and Find Full Text PDF

Objective: Clinical prediction models for surgical aortic valve replacement mortality, are valuable decision tools but are often limited in their ability to account for changes in medical practice, patient selection, and the risk of outcomes over time. Recent research has identified methods to update models as new data accrue, but their effect on model performance has not been rigorously tested.

Methods: The study population included 44,546 adults who underwent an isolated surgical aortic valve replacement from January 1, 1999, to December 31, 2018, statewide in Pennsylvania.

View Article and Find Full Text PDF

We previously found that T-cell acute lymphoblastic leukemia (T-ALL) requires support from tumor-associated myeloid cells, which activate Insulin Like Growth Factor 1 Receptor (IGF1R) signaling in leukemic blasts. However, IGF1 is not sufficient to sustain T-ALL in vitro, implicating additional myeloid-mediated signals in leukemia progression. Here, we find that T-ALL cells require close contact with myeloid cells to survive.

View Article and Find Full Text PDF
Article Synopsis
  • * While cardiac resynchronization therapy and implantable cardiac defibrillators can help certain patients with reduced ejection fraction, not everyone qualifies for these therapies.
  • * The article explores cardiac contractility modulation, a new therapy that aims to enhance quality of life and improve heart function for advanced heart failure patients, highlighting key clinical trials on its effectiveness.
View Article and Find Full Text PDF

Background: Developmental shifts in infant temperament predict distal outcomes including emerging symptoms of psychopathology in childhood. Thus, it is critical to gain insight into factors that shape these developmental shifts. Although parental depression and anxiety represent strong predictors of infant temperament in cross-sectional research, few studies have examined how these factors influence temperament trajectories across infancy.

View Article and Find Full Text PDF

Sickle cell disease (SCD) is a life-threatening condition. Given the nature of the disease and associated complications with high mortality and morbidity rates, it is imperative that patients are diagnosed in early infancy, are established with specialists and general pediatric care immediately, and receive continuity in care. A percentage of patients diagnosed with SCD fall within a vulnerable, at-risk population.

View Article and Find Full Text PDF

Latinx populations face a higher burden of kidney failure and associated negative outcomes compared with non-Latinx White populations, despite sharing a similar prevalence of CKD. Community health worker (CHW) interventions have been shown to improve outcomes for Latinx individuals, but they are largely underutilized in kidney disease. We convened a workshop of four ongoing kidney disease CHW programs to identify successes, challenges, potential solutions, and needed research to promote CHW programs for Latinx individuals with kidney disease.

View Article and Find Full Text PDF

Background: Empowering Veterans to age in place is a Department of Veterans Affairs priority. Family or unpaid caregivers play an important role in supporting Veterans to achieve this goal. Effectively meeting the needs of Veterans and caregivers requires identifying unmet needs and relevant gaps in resources to address those needs.

View Article and Find Full Text PDF

Pancreatic cancer is often diagnosed at an advanced stage and is frequently associated with severe pain. Traditional pain management in this condition may be improved with the use of topical diclofenac. A 39-year-old man with advanced pancreatic fibrosarcoma metastatic to the thoracic spine presented to the hospital with severe abdominal pain refractory to escalating doses of opioids.

View Article and Find Full Text PDF

Background: Engaging Hill-Sachs lesions (HSLs) pose a significant risk for failure of surgical repair of recurrent anterior shoulder instability. Reconstruction with fresh osteochondral allograft (OCA) has been proposed as a treatment for large HSLs.

Purpose: To determine the optimal characteristics of talus OCA bone plugs in a computer-simulated HSL model.

View Article and Find Full Text PDF

Trends in Procedural Closure of the Patent Ductus Arteriosus among Infants Born at 22 to 30 Weeks' Gestation.

J Pediatr

December 2023

Department of Pediatrics, Baylor University Medical Center, Dallas, TX; The Pediatrix Center for Research, Education, Quality, and Safety, Sunrise, FL. Electronic address:

Objective: To describe recent trend in procedural closure of the patent ductus arteriosus (PDA) among premature infants and compare the clinical characteristics of infants receiving surgical vs transcatheter closure.

Study Design: We conducted a descriptive, retrospective cohort study of preterm infants born between 22 and 29 weeks' gestation from 2014 through 2021. Infants were identified from the Pediatrix Clinical Data Warehouse.

View Article and Find Full Text PDF

The effect of biomechanical features on classification of dual-task gait.

IEEE Sens J

February 2023

Department of Physical Medicine and Rehabilitation, MetroHealth System, Cleveland, OH 44109 USA.

Early detection of Alzheimer's Disease and Related Disorders (ADRD) has been a focus of research with the hope that early intervention may improve clinical outcomes. The manifestation of motor impairment in early stages of ADRD has led to the inclusion of gait assessments including spatiotemporal parameters in clinical evaluations. This study aims to determine the effect of adding kinetic and kinematic gait features to classification of different levels of cognitive load in healthy individuals.

View Article and Find Full Text PDF
Article Synopsis
  • This study compares same-day discharge robotic-assisted radical prostatectomy to traditional inpatient procedures, motivated by the need for inpatient beds during the COVID-19 pandemic.
  • It involved 392 surgeries across two medical centers, analyzing complications, healthcare costs, and patient satisfaction within 30 days post-surgery.
  • Findings indicated similar complication rates, a significant cost reduction of about $2106, and no notable difference in patient satisfaction, suggesting same-day discharge is a viable option for selected patients.
View Article and Find Full Text PDF

In pediatric kidney failure, native kidneys may pose a risk to successful transplant outcomes. The indications and timing of native nephrectomy represent a controversial management decision. A lack of high-quality, outcomes-based data has prevented development of evidence-based guidelines for intervention.

View Article and Find Full Text PDF

Improving Diagnostic Accuracy in Skin of Color Using an Educational Module.

Cutis

July 2023

Drs. Kojder, Leszczynska, Riddle, Diaz, and Ahmed are from The University of Texas at Austin Dell Medical School. Drs. Kojder, Riddle, Diaz, and Ahmed are from the Division of Dermatology and Dermatologic Surgery, Department of Internal Medicine, and Dr. Leszczynska is from the Division of Pediatric Dermatology, Department of Pediatrics. Dr. Pisano is from the Department of Dermatology, Harvard Medical School, Boston, Massachusetts.

Dermatologic disparities disproportionately affect patients with skin of color (SOC). This study evaluated the effectiveness of a focused educational module for improving diagnostic accuracy and confidence in the treatment of patients with SOC among interprofessional health care providers. An SOC educational module involving a pretest, 15-minute lecture, immediate posttest, and 3-month posttest was created.

View Article and Find Full Text PDF
Article Synopsis
  • - Patients who undergo pelvic reconstructive surgery place significant importance on receiving guidance from surgeons about returning to sexual activity post-surgery.
  • - A study analyzed counseling practices among surgeons and identified six major themes, including the safety of intercourse, specific suggestions for enhanced experiences, and potential surgical complications.
  • - Overall, while surgeons typically reassure patients about safety, they tend to highlight that sexual experiences might be different or worse than before surgery, with less emphasis on potential improvements.
View Article and Find Full Text PDF