37 results match your criteria: "University of Texas M.D. Anderson Hospital and Tumor Institute at Houston.[Affiliation]"
Am J Clin Oncol
October 1987
Department of Hematology, University of Texas M.D. Anderson Hospital and Tumor Institute at Houston 77030.
South Med J
October 1987
Department of Hematology, University of Texas M. D. Anderson Hospital and Tumor Institute at Houston 77030.
Fifty-four patients aged 60 years or older with a diagnosis of chronic myelogenous leukemia were referred to University of Texas M. D. Anderson Hospital between 1965 and 1982.
View Article and Find Full Text PDFA dosimetric study of anterior electron beam irradiation for treatment of retinoblastoma was performed to evaluate the influence of tissue heterogeneities on the dose distribution within the eye and the accuracy of the dose calculated by a pencil beam algorithm. Film measurements were made in a variety of polystyrene phantoms and in a removable polystyrene eye incorporated into a tissue substitute phantom constructed from a human skull. Measurements in polystyrene phantoms were used to demonstrate the algorithm's ability to predict the effect of a lens block placed in the beam, as well as the eye's irregular surface shape.
View Article and Find Full Text PDFAm J Med
September 1987
Department of Hematology, University of Texas M.D. Anderson Hospital and Tumor Institute at Houston.
Two hundred forty-two patients with Philadelphia chromosome-positive chronic myelogenous leukemia in blast crisis were reviewed to identify significant biologic and prognostic associations. Twenty percent of patients had lymphoid blast crisis. Clonal evolution was present in 60 percent of patients at blast crisis and involved most frequently the development of a double Philadelphia chromosome, trisomy 8, or isochromosome 17.
View Article and Find Full Text PDFCancer Biochem Biophys
September 1987
Department of Tumor Biology, University of Texas M.D. Anderson Hospital and Tumor Institute at Houston 77030.
Retinoic acid (RA) inhibits the growth of mouse S91-C2 melanoma cells and enhances the glycosylation of a cell surface sialoglycoprotein (gp160). The present study analyzed the binding of 125I-labeled lectins to gp160 within polyacrylamide slab gels after electrophoretic separation of cellular macromolecules. Wheat germ agglutinin (WGA) and concanavalin A (Con A) bound to gp160 of RA-treated cells (RA-gp160) more extensively than to gp160 of control cells (C-gp160).
View Article and Find Full Text PDFJ Comput Assist Tomogr
November 1987
Department of Diagnostic Radiology, University of Texas M.D. Anderson Hospital and Tumor Institute at Houston 77030.
Fourteen patients with the diagnosis of leukemia and one with lymphoma developed systemic candidiasis. Involvement of the liver (15 patients), spleen (nine patients), and kidney (five patients) was diagnosed by clinical, CT, and pathologic findings. The CT findings ranged from low-density lesions (11 livers, nine spleens, and five kidneys) to hepatomegaly or hepatosplenomegaly.
View Article and Find Full Text PDFBiochemistry
August 1987
Department of Cell Biology, University of Texas M. D. Anderson Hospital and Tumor Institute at Houston 77030.
This report describes the application of a resonance energy transfer assay to determine the transbilayer distribution of 7-nitro-2,1,3-benzoxadiazol-4-yl (NBD)-labeled lipid analogues. The validity of this technique was established by determining the relationship between the distance of separation of lissamine rhodamine B labeled phosphatidylethanolamine (N-Rho-PE) acceptor lipid and NBD-labeled donor lipid and energy transfer efficiency. By determination of the distance between probes at 50% transfer efficiency (R0), the distance between fluorophores distributed symmetrically (outer leaflet label) and asymmetrically in artificially generated vesicles was determined.
View Article and Find Full Text PDFJ Chromatogr
July 1987
Department of Biochemistry and Molecular Biology, University of Texas M.D. Anderson Hospital and Tumor Institute at Houston 77030.
An ion chromatography procedure was devised for the simultaneous determination of phosphate and sulfate in the same sample. In order to eliminate interference from zwitterionic compounds (particularly amino acids and peptides) generated during hydrolysis of the phosphate- or sulfate-containing compounds a pretreatment step with a cation-exchange column was required. The detection of sulfate is approximately twice as sensitive as phosphate on a molar basis.
View Article and Find Full Text PDFA colloidal suspension of Co2B with avidin irreversibly adsorbed to the surface has been used with biotinylated antibodies and lectins to eliminate specific cell populations from mixtures with peripheral blood or bone marrows. Using the monoclonal antibodies CF-1 and PM-81 with this magnetic affinity colloid (MAC), we can eliminate five logs of K562 cells from mixtures with peripheral blood or marrow cells as determined by a linear limiting dilution clonogenic assay. We have also used this separation to eliminate clonogenic leukemia cells from fresh samples of peripheral blood and bone marrow from relapsed acute leukemia patients.
View Article and Find Full Text PDFAm J Pediatr Hematol Oncol
December 1987
Department of Pediatrics, University of Texas M.D. Anderson Hospital and Tumor Institute at Houston 77030.
Two cases of infants with congenital leukemia who had severe, refractory hypertensive reactions to teniposide (VM-26) are described. Patients on a 5 mg/kg twice weekly schedule of teniposide had hypertensive reactions in which their systolic blood pressure was greater than 200 mm Hg after the second dose of teniposide. Hypertension combined with myelosuppression resulted in the patient's death in one case.
View Article and Find Full Text PDFPediatr Radiol
January 1988
Department of Pediatrics, University of Texas M.D. Anderson Hospital and Tumor Institute at Houston.
The use of ultrasound to detect a response of massive Wilms' tumor to preoperative chemotherapy is demonstrated. Anechoic areas appearing during treatment are highly suggestive of response even in the absence of a reduction in size.
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