1,059 results match your criteria: "University of Texas Health Sciences Center-Houston; Houston[Affiliation]"

Collaborative outcomes study on health and functioning during infection times (COH-FIT): Insights on modifiable and non-modifiable risk and protective factors for wellbeing and mental health during the COVID-19 pandemic from multivariable and network analyses.

Eur Neuropsychopharmacol

January 2025

Charité Universitätsmedizin Berlin, Department of Child and Adolescent Psychiatry, Berlin, Germany; Department of Psychiatry, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, New York, USA; The Zucker Hillside Hospital, Northwell Health, New York, USA; Feinstein Institutes for Medical Research, Center for Psychiatric Neuroscience, Manhasset, New York, USA. Electronic address:

Article Synopsis
  • The COH-FIT study is a large, multi-country survey aimed at identifying factors affecting wellbeing and mental health outcomes during the COVID-19 pandemic, involving a representative sample of 121,066 adults.
  • Researchers analyzed both modifiable (like coping strategies and pre-pandemic stress) and non-modifiable factors (such as age, gender, and socioeconomic status), finding significant negative effects on wellbeing and psychopathology scores during the pandemic.
  • The study identified 15 modifiable and 9 non-modifiable risk factors, alongside 13 modifiable and 3 non-modifiable protective factors, emphasizing the importance of social support and coping strategies in mental health outcomes.
View Article and Find Full Text PDF

Global and risk-group stratified well-being and mental health during the COVID-19 pandemic in adults: Results from the international COH-FIT Study.

Psychiatry Res

December 2024

Charité Universitätsmedizin Berlin, Department of Child and Adolescent Psychiatry, Berlin, Germany; Department of Psychiatry, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, New York, USA; The Zucker Hillside Hospital, Northwell Health, New York, USA; The Feinstein Institute for Medical Research, Center for Psychiatric Neuroscience, Manhasset, NY, USA. Electronic address:

Article Synopsis
  • There is a lack of comprehensive international studies examining multidimensional mental health and wellbeing before and during the COVID-19 pandemic, particularly identifying at-risk groups and effective coping strategies.
  • The COH-FIT survey, conducted from April 2020 to June 2022 in 30 languages, assessed changes in well-being and psychopathology among over 121,000 participants, revealing significant declines in mental health during the pandemic.
  • Key findings indicated that certain demographics, such as young adults and people in low-income countries, were particularly affected, while coping strategies like exercise, internet use, and maintaining social contacts emerged as the most effective for managing stress.
View Article and Find Full Text PDF

Background: We aimed to assess the impact of complex mitral valve disease and patient risk profile on operative outcomes in the large cohort of the Mini-Mitral International Registry.

Methods: Patients were assigned to categories of complex degenerative mitral valve regurgitation (DMR; bileaflet or anterior mitral leaflet prolapse/flail) and simple DMR (posterior mitral leaflet prolapse/flail). Subgroup analyses was performed in low-risk (EuroSCORE II <8%) and high-risk (EuroSCORE II >8%) cohorts.

View Article and Find Full Text PDF

Out-of-school Activities and Adherence to 24-hour Movement Guidelines.

Am J Prev Med

January 2025

Department of Health Sciences, College of Health Professions and Sciences, University of Central Florida, Orlando, Florida.

Introduction: The purpose of this study was to explore associations between participation in out-of-school/weekend organized activities and adherence to the 24-hour movement guidelines among US adolescents.

Methods: Data from the 2022 National Survey of Children's Health (N=16,403, age=15.1±1.

View Article and Find Full Text PDF

LCS-1, a putative selective inhibitor of SOD1, is a substituted pyridazinone with rudimentary similarity to quinones and naphthoquinones. As quinones catalytically oxidize HS to biologically active reactive sulfur species (RSS), we hypothesized LCS-1 might have similar attributes. Here, we examine LCS-1 reactions with HS and SOD1 using thiol-specific fluorophores, liquid chromatography-mass spectrometry, electron paramagnetic resonance (EPR), UV-vis spectrometry, and oxygen consumption.

View Article and Find Full Text PDF

Survey of vitamin D supplementation practices in extremely preterm infants.

Pediatr Res

August 2024

Department of Pediatrics, Division of Perinatal-Neonatal Medicine, University of Texas Health Science Center Houston, McGovern Medical School, Houston, TX, USA.

Background: Most extremely preterm (EP) infants are vitamin D deficient (serum 25-hydroxyvitamin D levels below 20 ng/mL), and optimal supplementation practices for EP infants remain unknown. Our objective is to assess current vitamin D supplementation practices in U.S.

View Article and Find Full Text PDF
Article Synopsis
  • MEK inhibitors often lead to mucocutaneous toxicities that can interfere with cancer treatment, prompting a review of related literature to understand these side effects better.
  • The scoping review analyzed 227 relevant studies, revealing common toxicities like follicular reactions, ocular issues, dry skin, and eczema, with most cases being mild and manageable.
  • Recognizing and addressing these side effects early on is crucial to minimizing interruptions in cancer therapy.
View Article and Find Full Text PDF

This case report details a novel case of Wernicke encephalopathy (WE) in a 16-year-old boy with obesity and chronic cannabis use. Despite the absence of alcohol use disorder, this adolescent developed classic symptoms of WE, challenging the conventional diagnostic framework. Clinical suspicion for WE was supported by typical magnetic resonance imaging findings, low thiamine levels and rapid clinical improvement postintravenous thiamine supplementation.

View Article and Find Full Text PDF

Background: Triple negative breast cancer (TNBC) is an aggressive subtype with poor prognosis. We aimed to determine whether circulating tumor DNA (ctDNA) and circulating tumor cell (CTC) could predict response and long-term outcomes to neoadjuvant chemotherapy (NAC).

Methods: Patients with TNBC were enrolled between 2017-2021 at The University of Texas MD Anderson Cancer Center (Houston, TX).

View Article and Find Full Text PDF
Article Synopsis
  • The return of migrant partners can negatively affect the sexual health of women who remain in their communities, highlighting the need for targeted support and intervention.
  • A critical ethnographic study in Agua Dulce, Mexico involved 50 participants, including women, returnees, community leaders, and healthcare professionals, using various research methods like interviews and observations.
  • Findings showed that economic struggles and early separations lead to emotional distress for women, primarily due to infidelity concerns, highlighting the necessity for specialized health support and interventions.
View Article and Find Full Text PDF

Introduction: Whether circulating levels of sphingolipids are prospectively associated with cognitive decline and dementia risk is uncertain.

Methods: We measured 14 sphingolipid species in plasma samples from 4488 participants (mean age 76.2 years; 40% male; and 25% apolipoprotein E ( ε4 allele carriers).

View Article and Find Full Text PDF

Background: A growing population of patients with chronic kidney disease (CKD) presents with non-ST-segment-elevation myocardial infarction, although little is known about their longer-term mortality.

Methods And Results: Using the MINAP (Myocardial Ischaemia National Audit Project) registry, linked to Office for National Statistics mortality data, we analyzed 363 559 UK patients with non-ST-segment-elevation myocardial infarction, with or without CKD. Cox regression models were fitted, adjusting for baseline demographics.

View Article and Find Full Text PDF

Virtual Patient/Family Communication in the Acute Care Setting.

Stud Health Technol Inform

July 2024

University of Texas Health Science Center Houston, School of Biomedical Informatics, United States.

Patient and family-centered care strategies see patients and families as valuable healthcare team members and are therefore treated as essential clinical partners to achieve safe, high-quality care. Traditionally, hospitals have relied on physical presence as the primary strategy for including families in shared decision-making. During COVID-19, widespread visitor restrictions removed this primary strategy.

View Article and Find Full Text PDF

High cholesterol levels significantly contribute to the risk of atherosclerotic cardiovascular disease (ACVD), with a notable portion of ischemic heart disease cases linked to elevated cholesterol levels. Effective graphical displays of lipid panel tests and other cardiac risk factors are crucial for quick and accurate data interpretation, enabling early intervention for individuals with hyperlipidemia. Applying design theories such as Gestalt and distributed cognitive theories is essential for creating user-centered graphical data displays in the context of cardiovascular (CV) risk factors.

View Article and Find Full Text PDF

The pilot study explores how data visualization influences patient comprehension and engagement in understanding hyperlipidemia test results across diverse patient groups. Employing Gestalt theory and the Relational Information Display (RID) framework, intuitive visual tools were developed using Google Sheets, QlikView®, and Microsoft® Excel®. The survey conducted with patients used a Likert scale to evaluate six different line and bar graphs, each presenting the same LDL cholesterol data.

View Article and Find Full Text PDF

LPS-induced whole-blood cytokine production and depressive symptoms in dementia spousal caregivers: The moderating effect of childhood trauma.

Psychoneuroendocrinology

October 2024

Department of Psychological Sciences, Rice University, USA; Department of Psychology, University of Houston, USA; Department of Psychiatry, Baylor College of Medicine, USA; Department of Behavioral Science, MD Anderson Cancer Center, USA.

Unlabelled: Dementia spousal caregivers are at risk for adverse mental and physical health outcomes. Caregiver burden, anticipatory grief, and proinflammatory cytokine production may contribute to depressive symptoms among caregivers. People who report childhood trauma are more likely to have exaggerated stress responses that may also contribute to depressive symptoms in adulthood.

View Article and Find Full Text PDF

Arteriovenous malformations (AVMs) of the brain stem are very rare lesions accounting for 2% to 6% of the cerebral AVMs.1,2 They carry higher risk of hemorrhage3,4 and are associated with poor prognosis.5-7 This is a 27-year-old man who presented with intraventricular hemorrhage, hydrocephalus, and poor neurological status secondary to ruptured AVM.

View Article and Find Full Text PDF

The Role of Psychosocial Stress on Cardiovascular Disease in Women: JACC State-of-the-Art Review.

J Am Coll Cardiol

July 2024

Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA. Electronic address:

Psychosocial stress can affect cardiovascular health through multiple pathways. Certain stressors, such as socioeconomic disadvantage, childhood adversity, intimate partner violence, and caregiving stress, are especially common among women. The consequences of stress begin at a young age and persist throughout the life course.

View Article and Find Full Text PDF

The aim of this meta-meta-analysis was to systematically review randomised controlled trial (RCT) evidence examining the effectiveness of e- and m-Health interventions designed to improve physical activity, sedentary behaviour, healthy eating and sleep. Nine electronic databases were searched for eligible studies published from inception to 1 June 2023. Systematic reviews with meta-analyses of RCTs that evaluate e- and m-Health interventions designed to improve physical activity, sedentary behaviour, sleep and healthy eating in any adult population were included.

View Article and Find Full Text PDF

Blunted brachial blood flow velocity response to acute mental stress in PTSD females.

Physiol Rep

July 2024

Division of Physical Therapy and Rehabilitation Science, Department of Family Medicine and Community Health, University of Minnesota Medical School, Minneapolis, Minnesota, USA.

Post-traumatic stress disorder (PTSD) is associated with increased cardiovascular disease (CVD) risk. Compared with males, females are twice as likely to develop PTSD after trauma exposure, and cardiovascular reactivity to stress is a known risk factor for CVD. We aimed to examine hemodynamic responses to acute mental stress in trauma-exposed females with and without a clinical diagnosis of PTSD.

View Article and Find Full Text PDF
Article Synopsis
  • Pulmonary sarcomatoid carcinoma (PSC) is a rare and aggressive type of lung cancer that has both normal cell and unusual cell features.
  • Researchers studied PSC samples and compared them to normal lung tissues to understand their differences better, focusing on genetics and immune responses.
  • They found 27 gene mutations in PSC, discovered two types of PSC based on immune system activity, and noted that one type (Immune High) had better survival rates, showing that the immune system plays a big role in fighting this cancer.
View Article and Find Full Text PDF