11 results match your criteria: "University of Texas Health Science Center at Tyler Tyler[Affiliation]"
Article Synopsis
- High-resolution computed tomography (HRCT) is essential for diagnosing Idiopathic Pulmonary Fibrosis (IPF), but it can be confused with other interstitial lung diseases (ILDs) due to similar radiologic patterns.
- Researchers used mass spectrometry to analyze plasma extracellular vesicles (EVs) from different patient groups, identifying a five-protein signature that distinguishes IPF from other ILDs and healthy individuals.
- The study validated these biomarkers in independent cohorts, showing high accuracy but emphasizes the need for further large-scale studies to confirm their clinical application.
Nontuberculous mycobacteria (NTM) are environmentally acquired opportunistic pathogens that can cause chronic lung disease. Within the U.S.
View Article and Find Full Text PDFBackground: Health-related quality of life (HRQOL), a multifaceted construct for understanding health and healthcare outcomes, is comprised of eight domains of well-being and functioning over time and has become an essential factor in assessing outcomes for youth with obesity.
Aims: To evaluate the effect of a community based, lifestyle intervention, on obesity-specific HRQOL using the Sizing Me Up (SMU) in this group of Latino and White youth.
Materials And Methods: For this 12-week family and community-based intervention (ACT; Actively Changing Together), HRQOL was measured before and after the intervention concluded using the obesity-specific HRQOL tool, SMU.
Chk1 inhibition potentiates the therapeutic efficacy of PARP inhibitor BMN673 in gastric cancer.
Am J Cancer Res
March 2017
Department of Clinical Cancer Prevention, The University of Texas, MD Anderson Cancer Center Houston, TX, USA.
Globally, gastric cancer is the second leading cause of cancer deaths because of the lack of effective treatments for patients with advanced tumors when curative surgery is not possible. Thus, there is an urgent need to identify molecular targets in gastric cancer that can be used for developing novel therapies and prolonging patient survival. Checkpoint kinase 1 (Chk1) is a crucial regulator of cell cycle transition in DNA damage response (DDR).
View Article and Find Full Text PDFOvaries, estrogen, and longevity and long-term mortality associated with oophorectomy compared with ovarian conservation in the Nurses' Health Study and variation in ovarian conservation in women undergoing hysterectomy for benign indications.
Obstet Gynecol
August 2013
Department of Obstetrics and Gynecology University of Texas Southwestern Medical School Dallas, Texas Department of Surgery, University of Texas Health Science Center at Tyler Tyler, Texas.
In vitro activity of amikacin against isolates of Mycobacterium avium complex with proposed MIC breakpoints and finding of a 16S rRNA gene mutation in treated isolates.
J Clin Microbiol
October 2013
Mycobacteria/Nocardia Research Laboratory and the Department of Microbiology, UT Health Northeast (formerly The University of Texas Health Science Center at Tyler) Tyler, Texas, USA.
Amikacin is a major drug used for the treatment of Mycobacterium avium complex (MAC) disease, but standard laboratory guidelines for susceptibility testing are not available. This study presents in vitro amikacin MICs for 462 consecutive clinical isolates of the MAC using a broth microdilution assay. Approximately 50% of isolates had amikacin MICs of 8 μg/ml, and 86% had MICs of ≤16 μg/ml.
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