In Vitro Surface Testing Methods for Dental Implants-Interpretation and Clinical Relevance: A Review.

More than 2,000 dental implant options are estimated to be available for any given clinical situation. Because many implants have claims that are substantiated mainly on the basis of in vitro studies, it is prudent for clinicians to understand the interpretation of such studies and possible clinical relevance. In vitro tests can be segregated as surface analysis tests and mechanical assessment tests.

A Report of Three Cases from an Ongoing Prospective Clinical Study on a Novel Pink Biomimetic Implant System.

While, overall, dental implants are highly efficacious, consistently achieving predictable esthetic results can pose color-driven challenges at the implant/soft-tissue interface, particularly in the esthetic zone. An ongoing, 5-year, multicenter (eight sites) prospective study is following a total of 168 implants placed in 120 patients using a novel biomimetic (osteoconductive) implant system with pink collars and abutments that afford better gingival color matching, enhanced design variability, and streamlined fabrication and customization of the abutment/implant-tissue interface. The full results of this study will be published at the 3-year and 5-year timepoints; however, clinical analyses of the 18-month interim survival rates, marginal bone and soft-tissue level changes, and esthetics have been completed, showing an overall success rate among all of the implanted sites of 95.

Development of a customized whiteness index for dentistry based on CIELAB color space.

Objectives: To develop a customized CIELAB-based whiteness index for dentistry that accurately correlates to perception of tooth whiteness.

Methods: Four psychophysical experiments (PE1-4) were conducted by three panels of observers (OP1-3) under diffuse/0° observation/measuring conditions and under typical clinical viewing conditions. Nine whiteness indices (WI, Z%, WIC, WIO, W31, W64, W, WLAB, W*), two yellowness indices (YID1925, YIE313) and tint of white in the CIELAB color system (T) were compared with regard to their ability to measure the perceived whiteness of human teeth.

P2Y2 purinergic receptor activation is essential for efficient hepatocyte proliferation in response to partial hepatectomy.

Extracellular nucleotides via activation of P2 purinergic receptors influence hepatocyte proliferation and liver regeneration in response to 70% partial hepatectomy (PH). Adult hepatocytes express multiple P2Y (G protein-coupled) and P2X (ligand-gated ion channels) purinergic receptor subtypes. However, the identity of key receptor subtype(s) important for efficient hepatocyte proliferation in regenerating livers remains unknown.

In vivo bioreactors for mandibular reconstruction.

Large mandibular defects are difficult to reconstruct with good functional and aesthetic outcomes because of the complex geometry of craniofacial bone. While the current gold standard is free tissue flap transfer, this treatment is limited in fidelity by the shape of the harvested tissue and can result in significant donor site morbidity. To address these problems, in vivo bioreactors have been explored as an approach to generate autologous prefabricated tissue flaps.

Vital-dye-enhanced multimodal imaging of neoplastic progression in a mouse model of oral carcinogenesis.

In this longitudinal study, a mouse model of 4-nitroquinoline 1-oxide chemically induced tongue carcinogenesis was used to assess the ability of optical imaging with exogenous and endogenous contrast to detect neoplastic lesions in a heterogeneous mucosal surface. Widefield autofluorescence and fluorescence images of intact 2-NBDG-stained and proflavine-stained tissues were acquired at multiple time points in the carcinogenesis process. Confocal fluorescence images of transverse fresh tissue slices from the same specimens were acquired to investigate how changes in tissue microarchitecture affect widefield fluorescence images of intact tissue.

The judicial process: an overview from the TDA Council on Ethics and Judicial Affairs.

From time to time, the Council on Ethics and Judicial Affairs must investigate and act on the alleged unethical behavior of Texas Dental Association members. Because the alleged behavior is directed at a colleague and TDA member, the work of the council is neither comfortable nor inviting. Nonetheless, council decisions are made taking into account its mission to investigate the allegation between the parties and to improve dental ethics in the state.

Spotlight on bond strength testing--unraveling the complexities.

The variability in methods and outcomes of bond strength testing reports is well documented in the dental literature. Many studies lack important information, which impairs the ability to reproduce them as well as to compare them to other studies in the literature. In order to critically discuss the important issues around bond strength testing methods, and to move closer to at least standardizing the reporting of such studies, the Academy of Dental Materials held a conference in 2009 entitled Adhesion in Dentistry-Analyzing Bond Strength Testing Methods, Variables, and Outcomes.

Submental intubation: a literature review.

A literature review was performed to analyse the evidence supporting submental intubation and to aid in the development of a new airway algorithm in craniofacial surgery patients. A systematic search of Pub Med, OVID, the Cochrane Database and Google Scholar between January 1984 and April 2011 was performed. Measured variables included the outcome, complications, publishing specialty journal and method of intubation including technique modifications, indications for the procedure, devices utilized and the total procedure time to complete the submental intubation.

Living in limbo: ethics and experience in a conversation about persistent oral lesions.

This case report presents a conversation that the authors had with a patient who is suffering from oral lichen planus and oral cancer. The reason that the authors approached the patient for an interview was to find out why he decided to enroll in an experimental study related to his oral cancer. The patient reported that it was "the waiting" that led him to enroll in this study--that is, the pressure of waiting for oral cancer to re-emerge was simply unbearable, and enrolling in this experimental study enabled him to take a more proactive approach to his illness.

Fluoride varnish: the top choice for professionally applied fluoride.

Although various modes of delivery for professionally applied fluoride exist, one form has emerged that combines caries prevention efficacy with safety and versatility. The American Dental Association Council on Scientific Affairs recommends fluoride varnish as the only professionally applied fluoride for moderate to high risk patients of all age groups. In addition to demonstrating effectiveness equivalent to fluoride gels, fluoride varnish provides improved safety and acceptability.

Bond strength comparison of color change adhesives for orthodontic bonding.

This study investigated whether three different color change light-cured orthodontic bonding adhesives have comparable shear bond strengths to a conventional light-cured orthodontic bonding adhesive. The sample of 240 bovine incisors was divided into four groups of 60 each. Each group tested one of four orthodontic bonding adhesives: 3M Unitek Transbond PLUS, Ormco Gréngloo, Ormco Blúgloo, and 3M Unitek Transbond XT (control).

Teaching evidence-based practice at the University of Texas Dental Branch at Houston.

This brief report outlines the current curriculum for evidence-based practice at The University of Texas Dental Branch at Houston (UTDB). This curriculum is now based on the American Dental Association's Commission on Dental Accreditation 2010 Accreditation Standards for Dental Education Programs. Evidence-based practice is introduced to students in the first-year curriculum.

Dental trauma in children and adolescents with mental and physical disabilities.

Aim: to determine the occurrence of dental trauma in children and adolescents with a mental and/or physical disability compared to otherwise healthy children, and to assess factors associated with and mechanism of such trauma.

Methods: Eighty-six subjects consisting of 43 special needs and 43 otherwise healthy children between the ages of 8 and 15 years were chosen from the patient pool at Special Children's Dental Clinic within Children's Hospital, New Orleans. The study utilized a parent interview questionnaire and a clinical exam of the patient.

Bond strength comparison of color-change adhesives for orthodontic bonding using a self-etching primer.

Background: The purpose of this study was to compare the shear bond strengths of two color-change adhesives with a commonly used conventional light-cure adhesive while using a self-etching primer, and to compare any changes in shear bond strengths over time.

Methods: One hundred and eighty extracted bovine incisors were randomly divided into nine groups of 20 teeth each. The teeth were prepared with a self-etching primer (Transbond™ Plus) Metal lower incisor brackets were bonded directly to each tooth with two different color-change adhesives (TransbondPlus and Grēngloo™) and a control (Transbond XT).

Fimbriae of Porphyromonas gingivalis are important for initial invasion of osteoblasts, but not for inhibition of their differentiation and mineralization.

Background: Porphyromonas gingivalis is etiologically associated with chronic periodontitis. The major fimbriae of this periodontal pathogen mediate binding to host gingival epithelial cells and fibroblasts, a critical function in the initiation of periodontitis. However, the role of fimbriae in P.

Technique sensitivity in bonding to enamel and dentin.

Bonding to enamel and dentin has been among the most significant advancements in dentistry in the last five decades; extensive research and product development have resulted in more adhesive options. However, bonding to enamel and dentin still proves to be challenging, and selecting the correct product for a clinical application can be confusing. An incorrect choice can lead to insufficient bond strength.

Facial morphology of Finnish children with and without developmental hip dysplasia using 3D facial templates.

Background: Developmental dysplasia of the hip (DDH) is a condition that affects the femoral head and the acetabulum and leads to hip subluxation and dislocation. Infants with DDH are usually treated using splints that immobilize their hip joint and are forced on their back for long periods of time. The link between positioning and facial asymmetries is poorly understood.

Fluoride varnish: the top choice for professionally applied fluoride.

Although various modes of delivery for professionally applied fluoride exist, one form has emerged that combines caries prevention efficacy with safety and versatility. The American Dental Association Council on Scientific Affairs recommends fluoride varnish as the only professionally applied fluoride for moderate to high risk patients of all age groups. In addition to demonstrating effectiveness equivalent to fluoride gels, fluoride varnish provides improved safety and acceptability.

Weekly monitoring of the water fluoride content in a fluoridated metropolitan city--results after 1 year.

It continues to be the goal of the United States Department of Health and Human Services to fluoridate community water supplies to prevent dental caries. In Houston, Texas, where community water is assumed to contain in the range of 0.7-1.