Pandemic mothering: Mothers' experiences of adaptation and resilience during the COVID-19 pandemic.

Research suggests that the demands of have increased during the COVID-19 pandemic, especially for mothers. Widespread loss of childcare and in-person schooling forced parents to make adjustments to care for their children in new ways, many while working remotely. This qualitative study, guided by Walsh's theory of family resilience, examines mothers' experiences with stress and resilience as they adapted to the COVID-19 pandemic.

Preparing to intervene in intimate partner violence: An interprofessional safety planning and assessment simulation.

The healthcare system is often the point where intimate partner violence (IPV) can be identified and where intervention strategies are initiated. Healthcare workers often operate in silos; therefore, timely and appropriate intervention depends on effective interdisciplinary communication and teamwork. Interprofessional education initiatives are one method for promoting interdisciplinary cooperation.

Interprofessional Education for Domestic Violence Safety Planning in Nursing and Social Work: A Scoping Review.

Rationale: Nurses and social workers in healthcare settings are positioned to identify abuse and contribute to improving the wellbeing of victims and their family members by screening for, providing safety education about, and reporting abuse when required by law.

Objective: The review aims to assess the current state of the simulation education for addressing the needs of domestic violence (DV) survivors to screen, assess, and intervene in DV cases in healthcare settings.

Method: A scoping review to map the peer-reviewed evidence on interprofessional education (IPE) was conducted by means of automated database search for nursing and social work students.

How Can Clinical Communication Alleviate the Negative Impacts of Social Determinants of Health?: A Secondary HINTS 6 Dataset Analysis.

Structural disparities (eg, food insecurities, housing, and lack of transportation) at different social levels (eg, personal, family, and community) are strong determinants of health, influencing individuals' and population well-being worldwide. Research is scarce examining how clinical communication can mitigate the negative impact of social disparities obstructing the reception of quality healthcare. In this study, we explore the mediation role of patient-centered communication (PCC) between social determinants of health (SDH) and quality of care.

Substance Use Disorders Among Human Trafficking Victims: Evidence from the 2019 to 2021 Nationwide Emergency Department Sample.

Background: Human trafficking (HT) survivors are at risk for substance use disorder (SUD), although assessing the SUD epidemiology of HT survivors is difficult. This study used data from the 2019 to 2021 Nationwide Emergency Department Sample to estimate the prevalence of SUD for HT survivors utilizing emergency departments (ED) in the United States of America (US).

Methods: We included visits for patients aged 12-64 years with any International Classification of Diseases 10th Revision, Clinical Modification (ICD-10-CM) codes documenting HT as a cause of morbidity ( 1,688,  141) or history of HT ( 2,524,  218).

Risk Factors for Consensual and Coercive Sexual Hookup Behaviors among College Men: A Daily Diary Study.

Objective: Hookup behaviors (HUBs; i.e., sexual activity outside an exclusive relationship with no mutual expectation of romantic commitment) are prevalent on college campuses and are linked with alcohol use and sexual assault.

Two sides of trust: How cancer survivors' communication with healthcare providers and on social media predicted healthy behaviors during COVID-19.

Objectives: COVID-19 exacerbated pre-existing social inequalities. Using three theories linking clinical and media contexts to patients' health outcomes, our study investigated (1) potential factors of cancer patients' trust in healthcare providers and social media; (2) how such trust may influence healthy lifestyles during COVID-19.

Methods: Using structural equation modeling, we investigated effects of key patient-provider communication variables and media factors on healthy behaviors among cancer survivors (N = 1130) using a nationally representative dataset (HINTS-SEER restricted use files, January-July 2021).

Research advances in branched-chain amino acid metabolism in tumors.

The metabolic reprogramming of amino acids is an important component of tumor metabolism. Branched-chain amino acids (BCAAs) perform important functions in tumor progression. They are the important amino donor and are involved in the synthesis of various non-essential amino acids, nucleotides, and polyamines to satisfy the increased demand for nitrogen sources.

A systematic review of the toxic potential of parabens in fish.

Parabens are the most prevalent ingredients in cosmetics and personal care products (PCPs). They are colorless and tasteless and exhibit good stability when combined with other components. Because of these unique physicochemical properties, they are extensively used as antimicrobial and antifungal agents.

Characteristics and Models of Moisture Uptake in Fiber-Reinforced Composites: A Topical Review.

Fiber-reinforced composites are commonly exposed to environments associated with moisture and solution, resulting in uptake, which causes changes in the bulk resin, the fiber-matrix interface, and even the fiber itself. Knowledge about uptake behavior and diffusion mechanisms and characteristics are critical to better understanding the response of these materials to environmental exposure faced through service to developing better materials through selection of constituents and to the prediction of long-term durability. This paper reviews aspects of uptake mechanisms and subsequent response, as well as models that describe the sorption process, with the aim of providing a comprehensive understanding of moisture-uptake-related phenomena and characteristics such as uptake rate, diffusion and relaxation/deterioration constants, transitions in regimes, and overall response.

Adjusting Parenting Roles and Work Expectations among Women with Children during COVID-19.

This study explores mothers' experiences during the COVID-19 pandemic with a focus on stressors, parenting roles, and work expectations. Qualitative analysis of open-ended interviews with a diverse group of 44 mothers in the United States generated two main themes: adjusting parenting roles and career concerns for mothers. Findings reveal that mothers have both internalized strong intra-family expectations to shoulder the primary responsibility for domestic labor and childcare in addition to completing their work obligations and experience institutional gender bias in the expectations that employers have for female employees.

Interpretable medical image Visual Question Answering via multi-modal relationship graph learning.

Medical Visual Question Answering (VQA) is an important task in medical multi-modal Large Language Models (LLMs), aiming to answer clinically relevant questions regarding input medical images. This technique has the potential to improve the efficiency of medical professionals while relieving the burden on the public health system, particularly in resource-poor countries. However, existing medical VQA datasets are small and only contain simple questions (equivalent to classification tasks), which lack semantic reasoning and clinical knowledge.

Both enantiomers of β-aminoisobutyric acid BAIBA regulate Fgf23 via MRGPRD receptor by activating distinct signaling pathways in osteocytes.

With exercise, muscle and bone produce factors with beneficial effects on brain, fat, and other organs. Exercise in mice increased fibroblast growth factor 23 (FGF23), urine phosphate, and the muscle metabolite L-β-aminoisobutyric acid (L-BAIBA), suggesting that L-BAIBA may play a role in phosphate metabolism. Here, we show that L-BAIBA increases in serum with exercise and elevates Fgf23 in osteocytes.

Assessing Target Specificity of the Small Molecule Inhibitor MARIMASTAT to Snake Venom Toxins: A Novel Application of Thermal Proteome Profiling.

New treatments that circumvent the pitfalls of traditional antivenom therapies are critical to address the problem of snakebite globally. Numerous snake venom toxin inhibitors have shown promising cross-species neutralization of medically significant venom toxins in vivo and in vitro. The development of high-throughput approaches for the screening of such inhibitors could accelerate their identification, testing, and implementation and thus holds exciting potential for improving the treatments and outcomes of snakebite envenomation worldwide.

Room Temperature Diels-Alder Reactions of 4-Vinylimidazoles.

In the course of studying Diels-Alder reactions of 4-vinylimidazoles with -phenylmaleimide, it was discovered that they engage in cycloaddition at room temperature to give high yields of the initial cycloadduct as a single stereoisomer. In certain cases, the product precipitated out of the reaction mixture and could be isolated by simple filtration, thereby avoiding issues with aromatization observed during chromatographic purification. Given these results, intramolecular variants using doubly activated dienophiles were also investigated at room temperature.

Magnetoencephalography Atlas Viewer for Dipole Localization and Viewing.

Magnetoencephalography (MEG) is a noninvasive neuroimaging technique widely recognized for epilepsy and tumor mapping. MEG clinical reporting requires a multidisciplinary team, including expert input regarding each dipole's anatomic localization. Here, we introduce a novel tool, the "Magnetoencephalography Atlas Viewer" (MAV), which streamlines this anatomical analysis.

Association of HLA gene polymorphisms with Helicobacter pylori related gastric cancer-a systematic review.

The appropriate host cell immune responses for the progression of several diseases, including gastric or stomach cancer (GC), are significantly influenced by HLA polymorphisms. Our objective was to systematically review the evidence linking HLA polymorphisms with the risk of Helicobacter. pylori related GC.

Describing the male registered nursing workforce toward increasing male representation in professional nursing.

Background: Men are significantly underrepresented in nursing and increasing their numbers should be a priority.

Purpose: To describe the male nursing workforce in terms of size, demographics, education, and work settings.

Methods: Using data from the 2018 National Sample Survey of Registered Nurses, we performed a secondary descriptive analysis.

Safety and Academic Outcomes of College Campus-Based Advocacy Services.

Intimate partner violence (IPV), sexual assault, and stalking are consequential public health and safety issues with wide reaching impacts on emerging adults, including those on college campuses in the United States. In response to high rates of violence among college student populations, universities are developing campus-based advocacy (CBA) programs, which aim to support survivors of interpersonal violence through supportive connections, resource acquisition, and safety planning. However, little data exists related to their impact on key student-survivor outcomes.

L-β-aminoisobutyric acid, L-BAIBA, a marker of bone mineral density and body mass index, and D-BAIBA of physical performance and age.

As both L- and D-BAIBA are increased with exercise, we sought to determine if circulating levels would be associated with physical performance. Serum levels of L- and D-BAIBA were quantified in 120 individuals (50% female) aged 20-85 years and categorized as either a "low" (LP), "average" (AP) or "high" performing (HP). Association analysis was performed using Spearman (S) and Pearson (P) correlation.

γ-Aminobutyric acids (GABA) and serum GABA/AABA (G/A) ratio as potential biomarkers of physical performance and aging.

Declining physical performance with age and disease is an important indicator of declining health. Biomarkers that identify declining physical performance would be useful in predicting treatment outcomes and identifying potential therapeutics. γ-aminobutyric acid (GABA), a muscle autocrine factor, is a potent inhibitor of muscle function and works as a muscle relaxant.

Pathophysiology and pharmacology course grades and prediction of success in a graduate nurse practitioner program.

Background: During a program review, faculty identified that nurse practitioner (NP) students who received a C grade in Advanced Pathophysiology (Patho) and Advanced Pharmacology (Pharm) appeared to perform poorly in the later NP management courses and on other program outcomes.

Purpose: The research aimed to determine whether grades in graduate Patho and Pharm courses could predict performance in NP management courses, program progression and completion, and certification pass rates.

Methodology: This research included deidentified student data from 2016 to 2018 across seven NP specialty tracks ( n = 4,575).

Loss of Ptpmt1 limits mitochondrial utilization of carbohydrates and leads to muscle atrophy and heart failure in tissue-specific knockout mice.

While mitochondria in different tissues have distinct preferences for energy sources, they are flexible in utilizing competing substrates for metabolism according to physiological and nutritional circumstances. However, the regulatory mechanisms and significance of metabolic flexibility are not completely understood. Here, we report that the deletion of , a mitochondria-based phosphatase, critically alters mitochondrial fuel selection - the utilization of pyruvate, a key mitochondrial substrate derived from glucose (the major simple carbohydrate), is inhibited, whereas the fatty acid utilization is enhanced.

Linear regression: A beginner's guide for nursing research.

Linear regression is one of the most basic regression techniques used in research statistics, particularly nursing research. This article explains linear regression in detail.