1 results match your criteria: "University of Tennessee Health Science Center and Center for Cancer Research[Affiliation]"
Interferon-resistant Daudi cell line with a Stat2 defect is resistant to apoptosis induced by chemotherapeutic agents.
J Biol Chem
October 2009
Department of Pathology and Laboratory Medicine, University of Tennessee Health Science Center and Center for Cancer Research, Memphis, Tennessee 38163. Electronic address:
Interferon-alpha (IFNalpha) has shown promise in the treatment of various cancers. However, the development of IFN resistance is a significant drawback. Using conditions that mimic in vivo selection of IFN-resistant cells, the RST2 IFN-resistant cell line was isolated from the highly IFN-sensitive Daudi human Burkitt lymphoma cell line.
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