Photomechanical photochromism in a cetyltrimethylammonium isopolytungstate.

The photochromic properties of a hybrid compound comprised of the surfactant cation cetyltrimethylammonium [(CH)N(CH)] (CTA) and the isopolytungstate anion [HWO] is investigated. The compound, which has the nominal formula (CTA)[HWO]Cl·2HO, changes from white to blue when exposed to UV radiation. The sample returns to the bleached state if stored in the dark-ambient.

A Comprehensive Guide for Performing Sample Preparation and Top-Down Protein Analysis.

Methodologies for the global analysis of proteins in a sample, or proteome analysis, have been available since 1975 when Patrick O'Farrell published the first paper describing two-dimensional gel electrophoresis (2D-PAGE). This technique allowed the resolution of single protein isoforms, or proteoforms, into single 'spots' in a polyacrylamide gel, allowing the quantitation of changes in a proteoform's abundance to ascertain changes in an organism's phenotype when conditions change. In pursuit of the comprehensive profiling of the proteome, significant advances in technology have made the identification and quantitation of intact proteoforms from complex mixtures of proteins more routine, allowing analysis of the proteome from the 'Top-Down'.

A Subambient Open Roof Surface under the Mid-Summer Sun.

stays below ambient temperature under maximum solar intensities of mid-summer. It is found to be 11 °C cooler than a commercial white cool roof nearby. A combination of specially chosen polymers and a silver thin film yields values near 100% for both solar reflectance, and thermal emittance at infrared wavelengths from 7.

Curcumin and its derivatives: their application in neuropharmacology and neuroscience in the 21st century.

Curcumin (diferuloylmethane), a polyphenol extracted from the plant Curcuma longa, is widely used in Southeast Asia, China and India in food preparation and for medicinal purposes. Since the second half of the last century, this traditional medicine has attracted the attention of scientists from multiple disciplines to elucidate its pharmacological properties. Of significant interest is curcumin's role to treat neurodegenerative diseases including Alzheimer's disease (AD), and Parkinson's disease (PD) and malignancy.