The nexus of family environment with youth street criminal behavior in Khyber Pakhtunkhwa Pakistan.

This empirical work focuses on the impact of unsupportive and harsh family practices on youth criminal behaviour. The present study hypothesizes that the harsh practices and low support of a family are the contributing factors for street crimes and that family practices increase the intensity of youth street criminality, particularly in a Pakistani society. While studying youth delinquent behaviour in a Pakistani society, this study employs general strain theory (GST), which has not been employed in any research in Pakistan till date.

COVID-19 Infection in Pregnancy: A Review.

Coronavirus disease 2019 (COVID-19), which is a highly contagious viral illness caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has had a catastrophic effect on the world's demographics, resulting in more than 3.8 million deaths worldwide and establishing itself as the most serious global health crisis since the 1918 influenza pandemic. Several questions remain unanswered regarding the effects of COVID-19 disease during pregnancy.

Green synthesis of SrO bridged LaFeO/g-CN nanocomposites for CO conversion and bisphenol A degradation with new insights into mechanism.

Very recently the green synthesis routes of nanomaterials have attracted massive attention as it overcome the sustainability concerns of conventional synthesis approaches. With this heed, in this novel research work we have synthesized the g-CN nanosheets based nanocomposites by utilizing Eriobotrya japonica as mediator and stabilizer agent. Our designed bio-caped and green g-CN nanosheets based nanocomposites have abundant organic functional groups, activated surface and strong adsorption capability which are very favorable for conversion CO into useful products and bisphenol A degradation.

One-step sonochemical fabrication of biomass-derived porous hard carbons; towards tuned-surface anodes of sodium-ion batteries.

A facile one-step sonochemical activation method is utilized to fabricate biomass-derived 3D porous hard carbon (PHC-1) with tuned-surface and is compared with the conventional two-step activation method. As raw biomass offers good KOH impregnation, ultrasonication power diffuses both K and OH ions deep into its interior, creating various nanopores and attaching copious functional groups. In contrast, conventional activation lacks these features under the same carbonization/activation parameters.

Determination and Characterization of Phenolic Compounds from Australia-Grown Sweet Cherries ( L.) and Their Potential Antioxidant Properties.

Sweet cherries ( L.) are popular fruits around the world with a high nutritional value and abundant phenolic compounds. Phenolic compounds of cherries contribute to positive health benefits.

Screening of Marine Compounds as an Emerging and Promising Approach against Estrogen Receptor Alpha-Positive Breast Cancer.

Presently, the majority of breast tumors are estrogen receptor (ER) positive. Breast cancer (BC) is defined by uncontrolled cell proliferation (CP) in breast tissue. BCs are caused by the overexpression of genes that promote CP in breast cells.

Anti-hyperglycemic and anti-hyperlipidemic effects of a methanolic extract of Debregeasia salicifolia in Alloxan-induced diabetic albino mice.

Diabetes mellitus (DM), an endocrine syndrome characterized by high blood glucose levels due to abrogated insulin activity. The existing treatments for DM have side effects and varying degrees of efficacy. Therefore, it is paramount that novel approaches be developed to enhance the management of DM.

Impacts of mining on local fauna of wildlife in District Mardan & District Mohmand Khyber Pakhtunkhwa Pakistan.

Mining is vital for human sustenance and a crucial sector in the state economy. However, its impacts on the environment and biodiversity cannot be underestimated. Which are potent to the attract government's attention.

Ethnomedicinal and traditional uses of the Ferns of Khyber Pakhtunkhwa, Pakistan.

Ferns are often used by indigenous people in Khyber Pakhtunkhwa, Pakistan. This study was designed to collect the ethnomedicinal and traditional knowledge of these locals about this group of vascular plants. Forty taxa belong to nineteen genera and ten families are used in the treatment of different diseases.

Anticancer effects of acteoside: Mechanistic insights and therapeutic status.

Cancer, the uncontrolled proliferation and metastasis of abnormal cells, is a major public health issue worldwide. To date, several natural compounds have been reported with their efficacy in the treatment of different types of cancer. Chemotherapeutic agents are used in cancer treatment and prevention, among other aspects.

Hepatoprotective Screening of (Qazilb.) Y.R. Ling.

Investigation on medicinal plants' therapeutic potential has gained substantial importance in the discovery of novel effective and safe therapeutic agents. The present study is aimed at investigating the hepatoprotective potential of methanolic extract (SKM) against carbon tetrachloride- (CCl-) induced hepatotoxicity in rats. is one of the most imperative plants for its various pharmacological activities.

Improved Ocular Bioavailability of Moxifloxacin HCl using PLGA Nanoparticles: Fabrication, Characterization, and Evaluation.

Improving the bioavailability of a drug at the ocular surface presents a profound challenge. Due to ocular physiological barriers, conventional eye drops exhibit poor bioavailability of drugs. Sustained-release nanoparticles may improve the residence time and hence increase absorption of the drug from the corneal surface.

anticancer and antibacterial potentials of selected medicinal plants and isolation and characterization of a natural compound from .

In the current study, five different plants, , , , , and aqueous extracts were prepared and applied against the anticancer and antibacterial activities. It was observed that extract shows the highest anticancer activity with cell viability of 21.5%.

Hepatoprotective Potential of Pomegranate in Curbing the Incidence of Acute Liver Injury by Alleviating Oxidative Stress and Inflammatory Response.

Hepatitis is an inflammatory disease of the liver and is considered one of the leading causes of death worldwide. Due to its scavenging activity, may be used for the treatment and prevention of liver diseases. The current study investigated the protective mechanism underlying the effects of pomegranate against a rat model of carbon tetrachloride-induced liver injury.

Road and Transportation Lead to Better Health and Sustainable Destination Development in Host Community: A Case of China Pakistan Economic Corridor (CPEC).

Road and transportation plays a vital role in the sustainable development and prosperity of the area. This study investigates the impact of road and transportation on the health of the host community and its sustainable destination development. Data were collected from the host community and were analyzed through factor analysis and structure equation modeling to evaluate the in-hand data of the structural relationship.

Berberine as a Potential Anticancer Agent: A Comprehensive Review.

Berberine (BBR), a potential bioactive agent, has remarkable health benefits. A substantial amount of research has been conducted to date to establish the anticancer potential of BBR. The present review consolidates salient information concerning the promising anticancer activity of this compound.

Antibacterial Films of Alginate-CoNi-Coated Cellulose Paper Stabilized Co NPs for Dyes and Nitrophenol Degradation.

The development of a solid substrate for the support and stabilization of zero-valent metal nanoparticles (NPs) is the heart of the catalyst system. In the current embodiment, we have prepared solid support comprise of alginate-coated cellulose filter paper (Alg/FP) for the synthesis and stabilization of Co nanoparticles (NPs) named as Alg/FP@Co NPs. Furthermore, Alginate polymer was blended with 1 and 2 weight percent of CoNi NPs to make Alg-CoNi1/FP and Alg-CoNi2/FP, respectively.

Nucleo-cytoplasmic interactions affect the 5' terminal transcription of mitochondrial genes between the isonuclear CMS line UG93A and its maintainer line UG93B of kenaf (Hibiscus cannabinus).

Gene expression and translation in plant mitochondria remain poorly understood due to the complicated transcription of its mRNA. In this study, we report the 5' and 3' RNA extremities and promoters of five mitochondrial genes, atp1, atp4, atp6, atp9, and cox3. The results reveal that four genes (atp1, atp4, atp6, and cox3) are transcribed from multiple initiation sites but with a uniform transcript at the 3' end, indicating that heterogeneity of the 5' end is a common feature in the transcription of kenaf mitochondrial genes.

Antispasmodic Potential of Medicinal Plants: A Comprehensive Review.

Numerous medicinal plants have been utilized for the treatment of different types of diseases and disorders including gastrointestinal (GI) diseases. GI diseases are the most common complaints that normally affects the largest proportion of children and adolescents with overlapping clinical manifestation in diagnosis and medical needs. Drugs with antispasmodic effects are normally applied for the symptomatic treatment of contraction and cramping of smooth muscles in gastrointestinal diseases as well as in other critical clinical situations.

Garlic (Allium sativum L.): Its Chemistry, Nutritional Composition, Toxicity, and Anticancer Properties.

The current review discuss the chemistry, nutritional composition, toxicity, and biological functions of garlic and its bioactive compounds against various types of cancers via different anticancer mechanisms. Several scientific documents were found in reliable literature and searched in databases viz Science Direct, PubMed, Web of Science, Scopus, and Research Gate were carried out using keywords such as "garlic", "garlic bioactive compounds", "anticancer mechanisms of garlic", "nutritional composition of garlic", and others. Garlic contains several phytoconstituents with activities against cancer, and compounds such as diallyl trisulfide (DATS), allicin, and diallyl disulfide (DADS), diallyl sulfide (DAS), and allyl mercaptan (AM).

60Co-γ Radiation Alters Developmental Stages of Zeugodacus cucurbitae (Diptera: Tephritidae) Through Apoptosis Pathways Gene Expression.

Radiation is considered as a promising insect pest control strategy for minimizing postharvest yield losses. Among various techniques, irradiation is a method of choice as it induces lethal biochemical or molecular changes that cause a downstream cascade of abrupt physiological abnormalities at the cellular level. In this study, we evaluated the effect of 60Co-γ radiation on various developmental stages of Zeugodacus cucurbitae Coquillett and subsequent carry-over effects on the progeny.

Crude extract and isolated bioactive compounds from Notholirion thomsonianum (Royale) Stapf as multitargets antidiabetic agents: in-vitro and molecular docking approaches.

Background: Diabetes mellitus is a common disease effecting the lifestyles of majority world population. In this research work, we have embarked the potential role of crude extracts and isolated compounds of Notholirion thomsonianum for the management diabetes mellitus.

Methods: The crude extracts of N.

Phyto-fabrication, purification, characterisation, optimisation, and biological competence of nano-silver.

Published studies indicate that virtually any kind of botanical material can be exploited to make biocompatible, safe, and cost-effective silver nanoparticles. This hypothesis is supported by the fact that plants possess active bio-ingredients that function as powerful reducing and coating agents for Ag+. In this respect, a phytomediation method provides favourable monodisperse, crystalline, and spherical particles that can be easily purified by ultra-centrifugation.

Antidiabetic Activity of Ficusonolide, a Triterpene Lactone from (Wall. ex Miq.): , , and Approaches.

Diabetes is a chronic condition which is locally managed through the stem of . To find the exact chemical constituent responsible for this activity, a triterpene lactone (ficusonolide) isolated from was studied for antidiabetic potential through the antidiabetic paradigm employing L-6 cells and an antidiabetic assay against non-insulin-dependent rats. The results on glucose uptake in the L-6 cell line indicated that ficusonolide has enhanced the uptake of glucose by 53.

Carbon Sequestration to Avoid Soil Degradation: A Review on the Role of Conservation Tillage.

Human efforts to produce more food for increasing populations leave marks on the environment. The use of conventional agricultural practices, including intensive tillage based on the removal of crop residue, has magnified soil erosion and soil degradation. In recent years, the progressive increase in the concentration of greenhouse gases (GHGs) has created global interest in identifying different sustainable strategies in order to reduce their concentration in the atmosphere.