Mediating Role of Job Satisfaction in the Relationship Between Leisure-Time Physical Activity and Emotional State of Healthcare Workers: A Cross-Sectional Survey.

Background: Work-related stress among healthcare employees can lead to burnout, worsened mood, and job dissatisfaction. Although physical activity is known to enhance mood and mental health, its impact on job satisfaction and emotional well-being in healthcare workers is under-researched. This study aimed to explore the associations between leisure-time physical activity (LTPA), job satisfaction, and emotional state and to investigate the mediating role of job satisfaction in the effect of LTPA on the emotional state of healthcare workers.

Effect of alemtuzumab on fatigue, quality of life, and patient/caregiver-reported outcomes in relapsing-remitting multiple sclerosis-A real-world evidence study.

Background: Alemtuzumab is approved in the European Union for treating highly active relapsing-remitting multiple sclerosis (RRMS). Patient-reported outcomes measure the treatment impact on quality of life (QoL), including fatigue, a common symptom in multiple sclerosis (MS). Chronic diseases like MS also affect the patient's caregiver.

Extracorporeal Shock Wave Therapy (ESWT) vs. Exercise in Thumb Osteoarthritis (SWEX-TO): Prospective Clinical Trial at 6 Months.

Rhizarthrosis is the most frequent form of osteoarthritis and is responsible for pain, disability and reduced functionality. The aim of the study is to investigate the clinical effects of shock wave treatment in patients suffering from arthritis of the first finger. A prospective clinical study was designed, in which 72 patients affected by rhizarthrosis were randomized to treatment with shock waves or exercises; in both groups an immobilization brace was used on the first finger.

Effect of Outdoor Cycling, Virtual and Enhanced Reality Indoor Cycling on Heart Rate, Motivation, Enjoyment and Intention to Perform Green Exercise in Healthy Adults.

Despite the benefits of physical activity (PA), Italy ranks low in leisure-time PA among European countries. Integrating virtual (VR)/enhanced (ER) reality with exercise equipment could boost PA engagement. Limited studies have explored how VR/ER-integrated cycling activity, compared to outdoor settings, influences PA among university students.

Multicomponent versus aerobic exercise intervention: Effects on hemodynamic, physical fitness and quality of life in adult and elderly cardiovascular disease patients: A randomized controlled study.

Objective: Cardiovascular diseases (CVDs) remain a leading cause of mortality globally, emphasizing the need for effective preventive measures. This study aimed to investigate the effects of a multicomponent compared to an aerobic training program on the hemodynamic parameters, physical fitness, psychophysical health status and quality of life (QoL) of adults and elderly with stabilized CVDs.

Methods: Thirty-three subjects (19M and 14F; age 69.

Cladribine effects on patient-reported outcomes and their clinical and biometric correlates in highly active relapsing multiple sclerosis at first switch: the observational, multicenter, prospective, phase IV CLADFIT-MS study.

Patient-reported outcomes (PROs) are essential for understanding the effects of MS and its treatments on patients' lives; they play an important role in multiple sclerosis (MS) research and practice. We present the protocol for an observational study to prospectively assess the effect of cladribine tablets on PROs and their correlation to disability and physical activity in adults with highly active relapsing MS switching from a first disease modifying drug (DMD) to cladribine tablets in routine clinical practice at study sites in Italy. The primary objective will be to evaluate changes from baseline in the impact of highly active MS on self-assessed physical functioning 52 weeks after the switch to cladribine tablets using the Multiple Sclerosis Impact Scale-29 (MSIS-29).

Ten-Minute Physical Activity Breaks Improve Attention and Executive Functions in Healthcare Workers.

Occupational health is a major problem in modern work environments. Physical activity breaks (PABs), short exercise periods delivered during working hours, incorporating exergames or outdoor activities, have emerged as a novel approach that could be used to improve work efficiency and workplace wellbeing. Therefore, this study aimed to investigate the impact of PABs on attention levels and executive functions in healthcare workers.

Special Issue "Health and Performance through Sports at All Ages 2.0".

This Special Issue, "Health and Performance through Sports at All Ages 2 [...

OPA1 mutation affects autophagy and triggers senescence in autosomal dominant optic atrophy plus fibroblasts.

In several cases of mitochondrial diseases, the underlying genetic and bioenergetic causes of reduced oxidative phosphorylation (OxPhos) in mitochondrial dysfunction are well understood. However, there is still limited knowledge about the specific cellular outcomes and factors involved for each gene and mutation, which contributes to the lack of effective treatments for these disorders. This study focused on fibroblasts from a patient with Autosomal Dominant Optic Atrophy (ADOA) plus syndrome harboring a mutation in the Optic Atrophy 1 (OPA1) gene.

Impact of Coastal Walking Outdoors and Virtual Reality Indoor Walking on Heart Rate, Enjoyment Levels and Mindfulness Experiences in Healthy Adults.

Outdoor exercise is beneficial for psychophysical well-being. Limited studies have compared outdoor and virtual reality (VR) indoor physical activities, especially in coastal settings. Therefore, this study aimed to assess the impact of outdoor coastal walking and indoor walking in a VR simulation with a similar environment on physiological and psychological variables in healthy adults.

Does body mass index distinguish motor proficiency, social and emotional maturity among adolescent girls?

Background: The objective of this study was to investigate whether different body mass index (BMI) groups could serve as a distinguishing factor for assessing motor proficiency and social and emotional maturity in adolescent girls.

Methods: 140 girls ranging from 12 to 14.5 years old were selected from the schools of Tabriz city, Iran.

A multicomponent physical activity home-based intervention for fibromyalgia patients: effects on clinical and skin biopsy features.

Objectives: Adapted physical activity (APA) has been recommended for fibromyalgia (FM) treatment as an essential component of a biopsychosocial therapeutic approach for patients. Previous studies report that aerobic and resistance training are the most effective programs in improving the quality of life and psycho-physical well-being. Patients with FM are frequently affected by an impairment of small fibers innervation, which is evident in the proximal somatic districts.

Effects of Cycling on Spine: A Case-Control Study Using a 3D Scanning Method.

Background: Few studies have investigated the effects of adopting a specific and prolonged posture on cyclists. This study aimed to evaluate the upright spine in a sample of recreational cyclists and compare it with a sample of non-cyclists, though still athletes, through a 3D scanning method.

Methods: Forty-eight participants were enrolled in this observational study.

Impacts of different triathlon races on systemic cytokine profile and metabolic parameters in healthy individuals: a systematic review.

The present systematic review aimed to discuss the impacts of different triathlon protocols on the level of pro and anti-inflammatory cytokines, as well as biomarkers related to the performance of healthy individuals. Four databases [PubMed (28 articles), Scopus (24 articles), Science Direct (200 articles), and SPORT Discus (1101 articles) were assessed. The eligibility criteria were applied, and the selected articles were used in the peer review, independently, as they were identified by March 2022.

Coenzyme Q10 Supplementation in Athletes: A Systematic Review.

Background: To summarize available evidence in the literature on the impacts of CoQ supplementation on metabolic, biochemical, and performance outcomes in athletes.

Methods: Six databases, Cochrane Library (33 articles), PubMed (90 articles), Scopus (55 articles), Embase (60 articles), SPORTDiscus (1056 articles), and Science Direct (165 articles), were researched. After applying the eligibility criteria, articles were selected for peer review independently as they were identified by June 2022.

Evaluating the Asymmetry of Muscle Activation and Strength in Paralympic Powerlifting Athletes.

Background: Strength training is a complex task, as it requires a combination of many variables. In paralympic powerlifting (PP) asymmetries for the evaluation of activation, and static force indicators have been increasingly studied.

Objective: To investigate the asymmetries in the strength and muscle activation indicators, before and after a training session of PP athletes.

The role of exercise parameters on small extracellular vesicles and microRNAs cargo in preventing neurodegenerative diseases.

Physical activity (PA), which includes exercise, can reduce the risk of developing various non-communicable diseases, including neurodegenerative diseases (NDs), and mitigate their adverse effects. However, the mechanisms underlying this ability are not yet fully understood. Among several possible mechanisms proposed, such as the stimulation of brain-derived neurotrophic factor (BDNF), endothelial nitric oxide synthase (eNOS), insulin-like growth factor-1 (IGF-1), vascular endothelial growth factor (VEGF), and nerve growth factor (NGF), the possible involvement of particular vesicular structures enclosed in lipid membranes known as extracellular vesicles (EVs) has recently been investigated.

Effect of rearing system (free-range vs cage) on gut and muscle histomorphology and microbial loads of Italian White breed rabbits.

Objective: The growing consumers' interest on animal welfare has raised the request of products obtained by alternative rearing systems. The present study was conducted to assess the influence of housing system on gut and muscle morphology and on microbial load in rabbits reared under free-range (FR) and cage system (CS).

Methods: A total of forty weaned (35 days of age) male Italian White breed rabbits were allotted according to the rearing system, and at 91 days of age were randomly selected and slaughtered for the morphological evaluation of tissue from duodenum and longissimus lumborum.

Evaluation of the Training Session in Elite Paralympic Powerlifting Athletes Based on Biomechanical and Thermal Indicators.

Background: Paralympic powerlifting (PP) is performed on a bench press, aiming to lift as much weight as possible in a single repetition.

Purpose: To evaluate thermal asymmetry and dynamic force parameters with 45 and 80% 1 Repetition Maximum (1 RM) in PP athletes.

Methods: Twelve elite PP male athletes were evaluated before and after a training session regarding skin temperature (thermography) and dynamic force indicators (Average Propulsive Velocity-MPV, Maximum Velocity-VMax, and Power).

New regression models to predict fat mass in intermediate-level male padel players.

Purpose: Padel is a racquet team sport that has generated great interest in recent years, but the anthropometric and body composition characteristics of padel players have not widely been investigated. So, this study has a threefold aim: i) to draw two specific linear regression models to estimate fat mass from Dual X-ray Absorptiometry (DXA) to anthropometry or bioelectrical impedance analysis (BIA); ii) to provide a BIA-vector (BIVA) profile of intermediate level padel players; iii) to understand if anthropometric, body composition and handgrip strength differ among padel's roles.

Methods: Participants were 15 padel players (26.

How Do Football Playing Positions Differ in Body Composition? A First Insight into White Italian Serie A and Serie B Players.

The present study aimed to investigate how playing positions differ in specific body composition variables in professional soccer players with respect to specific field zones and tactical lines. Five hundred and six Serie A and B professional soccer players were included in the study and analyzed according to their playing positions: goalkeepers (GKs), central backs (CBs), fullbacks (FBs), central midfielders (MIDs), wide midfielders (WMs), attacking midfielders (AMs), second strikers (SSs), external strikers (ESs), and central forwards (CFs), as well as their field zones (central and external) and tactical lines (defensive, middle, and offensive). Anthropometrics (stature and body mass) of each player were recorded.

Effectiveness of Vertical versus Horizontal Plyometric Training on Stretch-Shortening Cycle Performance Enhancement in Adolescent Soccer Players.

Plyometric exercise is a major tool for improving explosive actions. This study aimed to compare the efficacy of a vertical and horizontal plyometric training program on stretch-shortening performance variables in adolescent soccer players. Thirty-two male soccer players (aged 12.