422 results match your criteria: "University of St.Gallen[Affiliation]"

Public reporting in five health care areas: A comparative content analysis across nine countries.

Health Policy

December 2024

Chair of Health Economics, Policy and Management, School of Medicine, University of St. Gallen, St.-Jakob-Strasse 21, CH-9000 St Gallen, Switzerland.

Background: Public reporting is crucial to enhance transparency, accountability, and informed provider choice. Therefore, providing accessible and reliable information on provider performance and activities is key for all healthcare areas and the utilization of information by patients, providers and related audiences.

Objective: This study provides an extensive analysis of public reporting websites across nine high income countries, focusing on five healthcare areas, and aims to understand how these websites support patients in making informed choices about healthcare providers.

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Over the past few years, several software companies have emerged that offer process mining tools to assist enterprises in gaining insights into their process executions. However, the effective application of process mining technologies depends on analysts who need to be proficient in managing process mining projects and providing process insights and improvement opportunities. To contribute to a better understanding of the difficulties encountered by analysts and to pave the way for the development of enhanced and tailored support for them, this work reveals the challenges they perceive in practice.

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There has been a rapid expansion in the quantity and complexity of data, information and knowledge created in the behavioural and social sciences, yet the field is not advancing understanding, practice or policy to the extent that the insights warrant. One challenge is that research often progresses in disciplinary silos and is reported using inconsistent and ambiguous terminology. This makes it difficult to integrate and aggregate findings to produce cumulative bodies of knowledge that can be translated to applied settings.

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Success Factors of Growth-Stage Digital Health Companies: Systematic Literature Review.

J Med Internet Res

December 2024

Centre for Digital Health Interventions, School of Medicine, University of St. Gallen, St. Gallen, Switzerland.

Article Synopsis
  • Over the last decade, digital health technologies (DHTs) have rapidly developed, particularly due to electronic health records and the COVID-19 pandemic, but many companies like Pear Therapeutics and Proteus Digital Health have faced challenges scaling and some even went bankrupt.
  • The study aims to identify success factors for growth-stage DHT companies by examining general and specific factors, as well as variations among different companies within the sector.
  • Through a systematic review of 2972 studies, the research identified 52 success factors categorized into internal factors (like product and team composition) and external factors (including customers and regulatory influences).
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Background: The aging population highlights the need to maintain both physical and psychological well-being. Frailty, a multidimensional syndrome, increases vulnerability to adverse outcomes. Although physical exercise is effective, adherence among older adults with frailty is often low due to barriers.

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Responsible business conduct (RBC)-the corporate activities and initiatives that proactively address corporate involvement in human rights, environmental, and governance threats-has become an increasingly used means to counteract and prevent adverse effects of global businesses. Unlike other business sectors whose adverse impacts and RBC efforts (or lack thereof) are well documented, a comprehensive understanding of the state of commodity trading (CT), has been missing. In response, this paper uses a multidisciplinary literature review to provide an integrative understanding of the current state of research on the relationship between CT and RBC.

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Continual learning in the presence of repetition.

Neural Netw

November 2024

Department of Electrical Engineering, KU Leuven, Kasteelpark Arenberg 10, Leuven, 3001, Belgium. Electronic address:

Continual learning (CL) provides a framework for training models in ever-evolving environments. Although re-occurrence of previously seen objects or tasks is common in real-world problems, the concept of repetition in the data stream is not often considered in standard benchmarks for CL. Unlike with the rehearsal mechanism in buffer-based strategies, where sample repetition is controlled by the strategy, repetition in the data stream naturally stems from the environment.

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Background: Metabolic diseases, such as cardiovascular diseases and diabetes, contribute significantly to global mortality and disability. Wearable devices and smartphones are increasingly used to track and manage modifiable risk factors associated with metabolic diseases. However, no established guidelines exist on how to derive meaningful signals from these devices, often hampering cross-study comparisons.

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Background: The digitalization of health care organizations is an integral part of a clinician's daily life, making it vital for health care professionals (HCPs) to understand and effectively use digital tools in hospital settings. However, clinicians often express a lack of preparedness for their digital work environments. Particularly, new clinical end users, encompassing medical and nursing students, seasoned professionals transitioning to new health care environments, and experienced practitioners encountering new health care technologies, face critically intense learning periods, often with a lack of adequate time for learning digital tools, resulting in difficulties in integrating and adopting these digital tools into clinical practice.

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How to interpret patient-reported outcomes? - Stratified adjusted minimal important changes for the EQ-5D-3L in hip and knee replacement patients.

J Patient Rep Outcomes

November 2024

Chair of Health Economics, Policy, and Management, School of Medicine, University of St. Gallen, St. Jakob-Strasse 21, St. Gallen, SG, 9000, Switzerland.

Article Synopsis
  • The study focuses on calculating minimal important changes (MICs) for the EQ-5D-3L index score improvements after hip and knee replacements, using a large dataset to assess patient-reported outcome measures.
  • A retrospective analysis of data from over 500,000 surgeries revealed that MICs varied based on patient characteristics like pre-operative health status, depression, and sex.
  • Results indicated that patients with worse pre-operative scores needed larger MICs to notice improvement, with knee replacement patients generally requiring smaller MICs than those undergoing hip replacements.
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This study uncovers Taiwanese dual-earner couples' monetary practices and explores how the marriage institution is conceived of in the context of East Asian familism and the sweeping trend of individualism. Ample cross-national research has investigated household finances and money management among couples over time, yielding mostly Western-oriented insights. It is nevertheless matched with little evidence from East Asian societies that share similar trends of individualization.

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Land use change is crucial to addressing the existential threats of climate change and biodiversity loss while enhancing food security [M. Zurek , , 1416-1421 (2022)]. The interconnected and spatially varying nature of the impacts of land use change means that these challenges must be addressed simultaneously [H.

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Pharma innovation: how evolutionary economics is shaping the future of pharma R&D.

Drug Discov Today

December 2024

Technische Hochschule Ingolstadt, THI Business School, Esplanade 10, D-85049 Ingolstadt, Germany; University of St. Gallen, Institute of Technology Management, Dufourstrasse 40a, CH-9000 St. Gallen, Switzerland.

This paper describes the theory of evolutionary economics in the context of pharmaceutical R&D. In this context, the R&D productivity crisis acts as a key selection mechanism, and R&D, technology and industry trends provide mechanisms of variation. Drawing on today's prevailing business model among leading pharmaceutical companies, the biotech-leveraged pharma company (BIPCO), I propose two new value creation logics: the technology-investigating pharma company (TIPCO) and the asset-integrating pharma company (AIPCO).

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Background: Prolonged systemic inflammation is recognized as a major contributor to the development of various chronic inflammatory diseases. Daily measurements of inflammatory biomarkers can significantly improve disease monitoring of systemic inflammation, thus contributing to reducing the burden on patients and the health care system. There exists, however, no scalable, cost-efficient, and noninvasive biomarker for remote assessment of systemic inflammation.

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Background: Digital innovations can reduce the global burden of depression by facilitating timely and scalable interventions. In recent years, the number of commercial Digital Health Interventions for Depression (DHIDs) has been on the rise. However, there is limited knowledge on their content and underpinning scientific evidence.

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Disability-based discrimination in organizations.

Curr Opin Psychol

December 2024

Department of Business Economics, Hasselt University, Belgium.

This article selects recent developments within the research domain of disability in organizations, exemplified through rigorous and innovative studies. First, the interest in invisible disability types and intersectional approaches to disability is noted. Second, the expansion to stakeholders outside the firm is appraised and personal, organizational and societal aspects of managing disability at work are reviewed.

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Introduction: Clinical decision-making in oncology is a complex process, with the primary goal of identifying the most effective treatment tailored to individual cancer patients. Many factors influence the treatment decision: disease- and patient-specific criteria, the increasingly complex treatment landscape, market authorization and drug availability, financial aspects, and personal treatment expertise. In the domain of genitourinary cancers, particularly prostate cancer, decision-making is challenging.

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Introduction: Healthcare systems around the world exhibit inherent systemic inequities that disproportionately impact marginalised populations. Digital health technologies (DHTs) hold promising potential to address these inequities and to play a pivotal role in advancing health equity. However, there is a notable gap regarding a comprehensive and structured overview of existing frameworks and guidelines on advancing health equity and a clear understanding of the potential of DHTs in their implementation.

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Background: While the effectiveness of patient-reported outcome measures (PROMs) as an intervention to impact patient pathways has been established for cancer care, it is unknown for other indications. We assessed the cost-effectiveness of a PROM-based monitoring and alert intervention for early detection of critical recovery paths following hip and knee replacement.

Methods And Findings: The cost-effectiveness analysis (CEA) is based on a multicentre randomised controlled trial encompassing 3,697 patients with hip replacement and 3,110 patients with knee replacement enrolled from 2019 to 2020 in 9 German hospitals.

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Background: Radical prostatectomies can be performed using open retropubic, laparoscopic, or robot-assisted laparoscopic surgery. The literature shows that short-term outcomes (in particular, inpatient complications) differ depending on the type of procedure. To date, these differences have only been examined and confirmed in isolated cases based on national routine data.

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Background: A clinical dashboard is a data-driven clinical decision support tool visualizing multiple key performance indicators in a single report while minimizing time and effort for data gathering. Studies have shown that including patient-reported outcome measures (PROMs) in clinical dashboards supports the clinician's understanding of how treatments impact patients' health status, helps identify changes in health-related quality of life at an early stage, and strengthens patient-physician communication.

Objective: This study aims to determine design components for clinical dashboards incorporating PROMs to inform software producers and users (ie, physicians).

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Obesity has adverse consequences for those affected. We tested whether the association between obesity and its adverse consequences is reduced in regions in which obesity is prevalent and whether lower weight bias in high-obese regions can account for this reduction. Studies 1 and 2 used data from the United States ( = 2,846,132 adults across 2,546 counties) and United Kingdom ( = 180,615 adults across 380 districts) that assessed obesity's adverse consequences in diverse domains: close relationships, economic outcomes, and health.

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