1,185 results match your criteria: "University of Sri Jayewardenepura[Affiliation]"

Suspended sediment (SPS) triggers nitrogen retention by altering microbial network stability and electron transport behavior during the aerobic-anoxic transition.

J Environ Manage

December 2024

Shaanxi Key Laboratory of Environmental Engineering, Key Laboratory of Northwest Water Resource, Environment and Ecology, MOE, Xi'an University of Architecture and Technology, Xi'an, 710055, China; School of Environmental and Municipal Engineering, Xi'an University of Architecture and Technology, Xi'an, 710055, China. Electronic address:

NO-N transformation, the vital biological process, determines nitrogen removal and retention in aquatic environment. Suspended sediment (SPS) ubiquitous in freshwater ecosystems can accelerate the transitions from aerobic to anoxic states, inevitably impacting NO-N transformation. To elaborate on the microbial mechanism by which SPS content affected NO-N transformation, we explored nitrogen removal and retention, microbial communities, co-occurrence networks, and electron transfer behavior under different SPS content during the aerobic-anoxic transition.

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Phytochemistry and nutraceutical potential of Ceylon Cinnamomum species native to Sri Lanka.

Nat Prod Res

December 2024

Interdisciplinary Centre for Innovations in Biotechnology and Neuroscience, Faculty of Medical Sciences, University of Sri Jayewardenepura, Sri Lanka.

Cinnamon is a spice that is renowned for its several medicinal and cosmetic benefits. The research study examined the essential oil content, antioxidant, and anti-inflammatory properties of seven species native to Sri Lanka. Cinnamon bark and leaf samples were used to extract essential oils, methanol, and hexane.

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Background: In the United States, the Affordable Care Act (ACA) expanded public and private health coverage, increased health insurance affordability, reduced healthcare costs, and improved healthcare quality for many. Despite ACA provisions, lack of insurance and other factors continue to affect working-age women's access to primary care services.

Methods: We conducted a mixed-method systematic review to identify factors that affect women's access to primary care services since the ACA.

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Empyema necessitans (EN) is a rare condition characterized by the accumulation of pus in the extra-thoracic soft tissue due to decompression of intrathoracic empyema by extending through the parietal pleura and chest wall usually by . This is a report of a patient with poorly controlled diabetes mellitus type 2 presenting with high-grade fever, productive cough, dyspnoea and a left-sided pleuritic chest pain complicated by a left pleural effusion. It further extended to extra-thoracic soft tissue space without fistulation to the external environment.

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Background: Leptospirosis, a spirochaete infection, can lead to Leptospirosis Pulmonary Haemorrhage Syndrome (LPHS), which requires intensive care admission and has a high mortality. Although data on short-term outcomes are available, the long-term respiratory sequelae of LPHS survivors are not known. We aimed to identify the post-discharge pulmonary functions and functional limitations in survivors of LPHS.

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Article Synopsis
  • Carbapenem-resistant Enterobacteriaceae (CRE) are a significant health issue for cancer patients, with this study exploring their prevalence and the types of resistance genes present.
  • Among 165 bacterial isolates from cancer patients, 57% were Enterobacteriaceae, and 46.8% of these were found to be carbapenem-resistant, with Klebsiella pneumoniae being the most common strain.
  • The majority of the CRE strains produced carbapenemase, with the blaNDM gene being the most frequently detected, marking the first identification of blaVIM in Enterobacteriaceae in Sri Lanka.
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Funding and collaboration inequalities in infectious disease research - why does it matter?

Trends Microbiol

December 2024

Mahidol Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok, Thailand; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

To face the current and emerging challenges due to infectious diseases, global research communities must comprehend the challenges faced by scientists in low-income and lower-middle-income countries. Here we address pertinent issues regarding funding and collaboration inequalities that could potentially cripple economic and healthcare systems, escalating to bigger global threats.

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Long-acting injectable antipsychotic use in patients with bipolar disorder: Findings from the REAP-BD study.

Asian J Psychiatr

December 2024

Department of Psychiatry, Taipei City Hospital and Psychiatric Center, Taipei, Taiwan; Department of Psychiatry, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan. Electronic address:

Aims: This study aimed to assess treatment patterns and the effectiveness of long-acting injectable antipsychotics (LAIs) in patients with bipolar disorder (BD) across various Asian countries. The study focused on comparing the choices of LAIs, other psychotropic medications, and their psychotropic drug load to explore real-world usage and evaluate the potential benefits of LAIs in BD treatment across different countries.

Methods: A retrospective cohort study was conducted with BD patients diagnosed according to ICD-10-CM codes F31.

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Deposition of amyloid proteins in extracellular space can occur due to uncontrolled inflammatory processes. Tracheobronchial amyloidosis (TBA) is a rare form of such disease. A 68-year-old woman was evaluated for chronic cough following a COVID-19 infection.

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A DFT analysis of the antioxidant capacity of scopolin and scopoletin.

J Mol Model

November 2024

School of Agriculture, Food and Ecosystem Sciences, Faculty of Science, University of Melbourne, Royal Parade, Parkville, VIC, 3010, Australia.

Article Synopsis
  • Scopolin and scopoletin are natural antioxidants from the coumarin class that have exhibited radical scavenging properties, but their mechanisms of action were not well understood until this study.
  • Using Density Functional Theory (DFT) calculations, researchers found that scopoletin has a stronger antioxidant activity compared to scopolin, as indicated by its lower band gap energy and activation energy for radical scavenging.
  • The study identified hydrogen atom transfer (HAT) as the primary mechanism for both compounds in scavenging radicals, with scopolin and scopoletin showing significant differences in bond dissociation energies that influence their antioxidant capacities.
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Corrigendum to "Pandemic COVID-19 ends but soil pollution increases: Impacts and a new approach for risk assessment" [Sci. Total Environ. 890 (2023) 164070].

Sci Total Environ

December 2024

University of Wuppertal, School of Architecture and Civil Engineering, Institute of Foundation Engineering, Water- and Waste-Management, Laboratory of Soil- and Groundwater-Management, Pauluskirchstraße 7, 42285 Wuppertal, Germany; King Abdulaziz University, Faculty of Meteorology, Environment, and Arid Land Agriculture, Department of Arid Land Agriculture, 21589 Jeddah, Saudi Arabia; University of Kafrelsheikh, Faculty of Agriculture, Department of Soil and Water Sciences, 33516 Kafr El-Sheikh, Egypt.

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Mpox Outbreak in Previously Non-Endemic Countries: A Review on Impact on Asia.

Clin Pathol

November 2024

Department of Medicine, Faculty of Medical Sciences, University of Sri Jayewardenepura, Gangodawila, Nugegoda, Sri Lanka.

Mpox (human mpox) is an opportunistic viral zoonosis that bears a strong resemblance to smallpox. The virus is divided into 2 distinct clades, clade I and clade II, which were originally confined to the moist forest regions of Africa. However, due to air travel and the exotic pet trade, these clades have spread globally.

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Article Synopsis
  • Influenza A is a priority pathogen for the WHO due to its pandemic potential, leading to a study on its molecular epidemiology in the Western Province of Sri Lanka to inform vaccine selection and understand strain evolution.
  • The study involved 349 participants with respiratory symptoms, detecting Influenza A in 14%, B in 5.7%, and SARS-CoV-2 in 11.7% of cases, with some individuals having co-infections.
  • Genomic analysis revealed specific clades and subclades of H1N1 and H3N2 strains, along with several significant amino acid substitutions in the viral proteins, indicating ongoing viral evolution.
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Global burden of disease attributable to metabolic risk factors in adolescents and young adults aged 15-39, 1990-2021.

Clin Nutr

December 2024

MAFLD Research Center, Department of Hepatology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China; Key Laboratory of Diagnosis and Treatment for the Development of Chronic Liver Disease in Zhejiang Province, Wenzhou, China. Electronic address:

Article Synopsis
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Background: Leishmaniasis has emerged as an escalating public health problem in Sri Lanka, with reported cases increasing nearly three folds over past decade, from 1,367 in 2014 to 3714 cases in 2023. Phlebotominae sand flies are the vectors of leishmaniasis. Their density is known to be influenced by context-specific climatic and land use patterns.

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Wheat arabinoxylans: Insight into structure-function relationships.

Carbohydr Polym

January 2025

Department of Plant Sciences, North Dakota State University, Fargo, ND 58102, USA; Centre for Crop and Food Innovation, Food Futures Institute, Murdoch University, Western Australia 6150, Australia. Electronic address:

Arabinoxylan (AX), a key non-starch polysaccharide found in the cell walls of cereals like wheat, holds significant importance in the food industry. Recently, it has attracted attention due to its numerous health benefits. While the benefits of wheat arabinoxylans are well-established, a more comprehensive understanding of the relationship between their structure and functional properties is essential.

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Next-generation methods for precise pH detection in ocular chemical burns: a review of recent analytical advancements.

Anal Methods

November 2024

Key Laboratory of Advanced Materials of Tropical Island Resources of Ministry of Education and School of Chemical Engineering and Technology, Hainan University, Haikou, Hainan 570228, China.

Ocular burns due to accidental chemical spillage pose an immediate threat, representing over 20% of emergency ocular traumas. Early detection of the ocular pH is imperative in managing ocular chemical burns. Alkaline chemical burns are more detrimental than acidic chemical burns.

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Preservation of strawberries using jellyfish gelatin-based biodegradable films and coatings under refrigerated storage.

Food Sci Technol Int

November 2024

Department of Food Science and Technology, Faculty of Applied Sciences, University of Sri Jayewardenepura, Gangodawila, Nugegoda, Sri Lanka.

This study investigated the applicability of the biodegradable films and coatings prepared from gelatin extracted from jellyfish using two extraction methods; conventional hot water extraction and microwave-assisted extraction, for the preservation of strawberries under refrigerated storage (4 °C), compared to biodegradable films and coatings prepared from analytical grade cold water fish skin gelatin and porcine skin gelatin. After 21 days of storage, uncoated strawberries (control group) exhibited visual decay and fungal attacks while coated or film-wrapped strawberries exhibited a better appearance. Coating or wrapping with gelatin films significantly reduced the weight loss of strawberries and the changes in color, hardness, moisture content, pH, titratable acidity, and total soluble solids of coated/film-wrapped fruits during storage were minimal compared to the uncoated fruits.

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The hot water extract of senescent leaves from is used in traditional Sri Lankan medicine for treating diabetes mellitus. This study aimed to isolate phytochemicals in the ethyl acetate soluble fraction of the hot water extract. Bioassay-guided fractionation led to the isolation of three megastigmane derivatives and two hydroxybenzoic acid derivatives from fractions, demonstrating both hypoglycaemic and antidiabetic activities.

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Introduction: Carbapenems are used to treat multidrug-resistant organisms as last-resort antibiotics. Resistance to carbapenems is an emerging public health threat worldwide, with alarming reported rates in Asian countries. To minimise further spread of resistant strains and guide interventions, it is important to understand the prevalence rates and causative molecular determinants.

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Unlabelled: Pain is one of the most debilitating symptoms of cancer, substantially diminishing one's quality of life. The level of pain experienced is eventually determined by the pain coping strategies adopted by patients individually. The awareness of the 'self-coping methods of pain' of individual patients would be beneficial for the multidisciplinary pain team to consider such methods when planning future interventions to manage pain.

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In vitro analysis of XLAsp-P2 peptide loaded cellulose acetate nanofiber for wound healing.

J Pharm Sci

November 2024

Department of Chemistry, Faculty of Applied Sciences, University of Sri Jayewardenepura, Gangodawila, Nugegoda, Sri Lanka. Electronic address:

Recently, nanofiber-based wound dressings are currently a viable strategy to expedite the healing of wounds by providing a suitable microenvironment for tissue growth with active ingredients. This research study subjects the development of electrospun cellulose acetate (CA) nanofibers loaded with the XLAsp-P2, an antimicrobial peptide (AMP) that holds great potential for enhanced wound healing as a therapeutic agent. The synthesized XLAsp-P2-loaded CA nanofibers were fabricated via three loading percentages, 0.

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