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A subacute rabbit model for hepatobiliary dysfunction during total parenteral nutrition.
J Pediatr Gastroenterol Nutr
August 1989
Department of Pediatrics, Children's Hospital of Los Angeles, University of Southern California School of Medicine 90026.
Total parenteral nutrition (TPN) in children is associated with the complicating syndromes of cholestasis and cholelithiasis. The causes of these syndromes are not completely clear. Gastrointestinal hypomotility associated with enteral fasting may be involved in the pathogenesis of both syndromes.
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