1,366 results match your criteria: "University of Southern California Medical Center[Affiliation]"

Article Synopsis
  • COVID-19 patients hospitalized face an increased risk of venous thromboembolism (VTE) even with standard anticoagulant treatment, necessitating a revised protocol for dosage adjustments.
  • The study examined the effectiveness of a dynamic anticoagulation dosing guideline based on D-dimer levels, aiming to improve patient outcomes by allowing dose adjustments based on individual VTE risk.
  • Results indicated that patients whose anticoagulation was adjusted had a higher in-hospital survival rate (80.2%) compared to those on fixed doses (51.3%), though there was an increased rate of bleeding events in the adjusted group.
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A Survey on the Management of Patients with Severe Traumatic Brain Injury During Pregnancy: The MAMA Study.

Neurocrit Care

September 2024

Department of Anesthesia and Intensive Care, Istituto di Ricovero e Cura a Carattere Scientifico, Ospedale Policlinico San Martino, Genoa, Italy.

Article Synopsis
  • Trauma, particularly traumatic brain injury (TBI), is a significant cause of maternal mortality during pregnancy, yet there is a lack of guidelines for managing these cases.
  • An international survey with 122 physicians from 110 centers revealed that many do not have specific protocols for TBI in pregnant patients and highlighted a preference for using MRI and varying practices regarding transfusions and treatment methods.
  • The findings indicate substantial inconsistency in how severe TBI is managed in pregnant individuals, suggesting a need for more research and education to standardize care.
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Objective: To evaluate the association between wildfire exposure in pregnancy and spina bifida risk.

Methods: This retrospective cohort study used the California Office of Statewide Health Planning and Development Linked Birth File with hospital discharge data between 2007 and 2010. The Birth File data were merged with the California Department of Forestry and Fire Protection data of the same year.

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Article Synopsis
  • Current guidelines suggest that patients with isolated sternal fractures (ISFs) and minor heart-related issues should undergo 24-hour telemetry monitoring, despite a single study indicating they might not need it.
  • A study conducted across 8 trauma centers reviewed ISF patients with minor ECG changes or troponin elevation and found that very few (1.6%) experienced significant blunt cardiac injury (BCI), and none had BCI diagnosed via echocardiogram.
  • The results imply that routine monitoring and echocardiography may not be necessary for ISF patients displaying minor ECG abnormalities and challenge existing medical protocols.
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Article Synopsis
  • Basal cell carcinoma (BCC) is the most prevalent skin cancer in the U.S., particularly affecting Non-Hispanic Whites (NHW), but cases among Hispanics are on the rise, prompting this study to explore differences between these groups.
  • A retrospective analysis was conducted on 151 BCC samples from Hispanic and NHW patients at a medical center over two years, considering various patient and tumor characteristics.
  • Results indicated that Hispanic patients had a higher incidence of head and neck tumors and pigmented BCC, with significant differences in demographics and tumor histology compared to NHW patients.
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This field report describes the accessibility and perceived effectiveness of a free acupuncture program among a group of predominantly low-income Hispanic/Latino adults. Surveys, developed based on the Levesque Conceptual Framework of Access to Health Care, were administered to clients. Baseline ( = 245) and 6-week follow-up ( = 79) surveys were analyzed to document early program findings.

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Pituitary neuroendocrine tumors (PitNETs) exhibiting aggressive, treatment-refractory behavior are the rare subset that progress after surgery, conventional medical therapies, and an initial course of radiation and are characterized by unrelenting growth and/or metastatic dissemination. Two groups of patients with PitNETs were sequenced: a prospective group of patients (n = 66) who consented to sequencing prior to surgery and a retrospective group (n = 26) comprised of aggressive/higher risk PitNETs. A higher mutational burden and fraction of loss of heterozygosity (LOH) was found in the aggressive, treatment-refractory PitNETs compared to the benign tumors (p = 1.

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In the State of Hawaii, previous research has suggested that minority groups such as Native Hawaiians and Other Pacific Islanders are disproportionately affected by mental health disorders and have less access to mental health services. The purpose of this study was to determine if similar disparities in the prevalence of psychiatric disorders among different ethnic groups are also present among Hawaii's houseless population. A retrospective chart review of records from one of Oahu's major houseless outreach clinics was performed to gather patient demographics and reported histories of psychiatric diagnoses.

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Compensatory tachycardia, an increased heart rate responding to stressors, requires careful consideration in treatment. This case report outlines a scenario where emergency medical services (EMS) misinterpreted a patient's electrocardiogram (EKG) as paroxysmal supraventricular tachycardia (PSVT) and administered adenosine, resulting in sudden cardiac arrest. Despite the rarity of deaths post-adenosine, this case highlights the potential risks of its use in inappropriate clinical scenarios.

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Background And Aims: Pseudocirrhosis is a poorly understood acquired morphologic change of the liver that occurs in the setting of metastatic malignancy and radiographically resembles cirrhosis. Pseudocirrhosis has been primarily described in metastatic breast carcinoma, with few case reports arising from other primary malignancies. We present 29 cases of pseudocirrhosis, including several cases from primary malignancies not previously described.

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Study Objective: This study aimed to determine the effect of the implementation of the Enhanced Recovery After Surgery (ERAS) protocol among patients receiving minimally invasive gynecologic surgery.

Design And Setting: This retrospective cohort study was performed in a tertiary care hospital.

Patients: A total of 328 females who underwent minimally invasive gynecologic surgeries requiring at least one overnight stay at Keck Hospital of University of Southern California (USC), California, USA, from 2016 to 2020 were included in this study.

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The coronavirus disease 2019 (COVID-19) pandemic posed new challenges in health care delivery for patients of all ages. These included inadequate personal protective equipment, workforce shortages, and unknowns related to a novel virus. Children have been uniquely impacted by COVID-19, both from the system of care and socially.

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Background: Motorcycle crashes pose a persistent public health problem with disproportionate rates of severe injuries and mortality. This study aims to analyze injury patterns and outcomes with regard to helmet use. We hypothesized that helmet use is associated with fewer head injuries and does not increase the risk of cervical spine injuries.

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Gaps in plastic surgery training: A comparative literature review of assessment tools in plastic surgery and general surgery.

J Plast Reconstr Aesthet Surg

December 2023

Division of Plastic and Reconstructive Surgery, Keck School of Medicine at University of Southern California, Los Angeles, CA, USA; Los Angeles County/University of Southern California Medical Center, Los Angeles, CA, USA. Electronic address:

Assessment tools for grading technical and nontechnical skills, such as operative technique and professionalism, are well established in general surgery. Less is known regarding the application of these tools in plastic surgery training. This study is a comparative review of the most prevalent assessment tools and rubrics utilized in general and plastic surgery.

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The Fifth Artificial Pancreas Workshop: Enabling Fully Automation, Access, and Adoption was held at the National Institutes of Health (NIH) Campus in Bethesda, Maryland on May 1 to 2, 2023. The organizing Committee included representatives of NIH, the US Food and Drug Administration (FDA), Diabetes Technology Society, Juvenile Diabetes Research Foundation (JDRF), and the Leona M. and Harry B.

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Background: Many fungal species are associated with the pathogenesis of allergic disease, yet most epidemiologic studies on IgE-mediated fungal sensitization have only included a few species.

Objective: We investigated fungal allergen sensitization prevalence, risk factors, and geographic variation in the United States.

Methods: From 2014 to 2019, a total of 7,912,504 serum-specific IgE (sIgE) test results for 17 fungal species were measured in 1,651,203 patients aged 0-85 years by a US-wide clinical laboratory.

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Purpose Of Review: This review aims to access the current state of the evidence in exercise as medicine for cardio-oncology in Hispanic and Latina breast cancer survivors and to provide our preliminary data on the effects of supervised aerobic and resistance training on cardiovascular disease (CVD) risk in this population.

Recent Findings: Breast cancer survivors have a higher risk of CVD; particularly Hispanic and Latina breast cancer survivors have a higher burden than their White counterparts. Exercise has been shown to reduce CVD risk in breast cancer survivors; however, evidence in Hispanic and Latina breast cancer survivors is scarce.

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Importance: There is variability in practice and imaging usage to diagnose cervical spine injury (CSI) following blunt trauma in pediatric patients.

Objective: To develop a prediction model to guide imaging usage and to identify trends in imaging and to evaluate the PEDSPINE model.

Design, Setting, And Participants: This cohort study included pediatric patients (<3 years years) following blunt trauma between January 2007 and July 2017.

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Objectives: Existing endoscopic scores for ulcerative colitis (UC) objectively categorize disease severity based on the presence or absence of endoscopic findings; therefore, it may not reflect the range of clinical severity within each category. However, inflammatory bowel disease (IBD) expert endoscopists categorize the severity and diagnose the overall impression of the degree of inflammation. This study aimed to develop an artificial intelligence (AI) system that can accurately represent the assessment of the endoscopic severity of UC by IBD expert endoscopists.

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Emergency department thoracotomy in children: A Pediatric Trauma Society, Western Trauma Association, and Eastern Association for the Surgery of Trauma systematic review and practice management guideline.

J Trauma Acute Care Surg

September 2023

From the Division of General Surgery (L.S., L.-Y.W., S.D.), Oregon Health & Sciences University, Portland, Oregon; Department of Surgery (B.Y., M.C.), University of Florida College of Medicine-Jacksonville, Florida; Department of Surgery (M.M.), Los Angeles County + University of Southern California Medical Center, Los Angeles, California; Department of Surgery (G.N.), Texas Tech University Health Sciences Center El Paso, El Paso, Texas; Division of Acute Care Surgery (K.M.), Loma Linda University Medical Center, Loma Linda, California; Department of Surgery (R.I.), University of California San Diego School of Medicine/Rady Childrens Hospital San Diego, San Diego, California; Department of Surgery (J.F.), Burnett School of Medicine at Fort Worth, Texas; Department of Surgery (S.W.L.), East Carolina University, Greenville, North Carolina; Department of Surgery (C.G.), University of Texas Health San Antonio, San Antonio, Texas; Department of Pediatric Surgery (K.T.F.-B.), Medical College of Wisconsin, Children's Wisconsin, Milwaukee, Wisconsin; and Division of Pediatric Surgery (M.J.), Doernbecher Children's Hospital, Oregon Health & Sciences University; and Randall Children's Hospital (M.J.), Legacy Emanuel Medical Center, Portland, Oregon.

Background: The role of emergency department resuscitative thoracotomy (EDT) in traumatically injured children has not been elucidated. We aimed to perform a systematic review and create evidence-based guidelines to answer the following PICO (population, intervention, comparator, and outcome) question: should pediatric patients who present to the emergency department pulseless (with or without signs of life [SOL]) after traumatic injuries (penetrating thoracic, penetrating abdominopelvic, or blunt) undergo EDT (vs. no EDT) to improve survival and neurologically intact survival?

Methods: Using Grading of Recommendations Assessment, Development and Evaluation methodology, a group of 12 pediatric trauma experts from the Pediatric Trauma Society, Western Trauma Association, and Eastern Association for the Surgery of Trauma assembled to perform a systematic review.

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Importance: Practice guidelines often provide recommendations in which the strength of the recommendation is dissociated from the quality of the evidence.

Objective: To create a clinical guideline for the diagnosis and management of adult bacterial infective endocarditis (IE) that addresses the gap between the evidence and recommendation strength.

Evidence Review: This consensus statement and systematic review applied an approach previously established by the WikiGuidelines Group to construct collaborative clinical guidelines.

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Beyond Defibrillation During Immersion: Case Illustrates Value of Heatstroke Treatment Protocols.

Ann Emerg Med

August 2023

Global Consortium on Climate and Health Education, Columbia University, New York, NY; Department of Environmental Health Sciences, Mailman School of Public Health, New York, NY; Department of Emergency Medicine, Columbia University Irving Medical Center, New York, NY.

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This commentary article discusses the benefits of utilizing telemedicine to conduct shared medical appointments for people with type 1 diabetes and type 2 diabetes. We conducted a literature review of articles about shared medical appointments or group medical visits in people with diabetes with associated clinical data. We identified 43 articles.

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