1,425 results match your criteria: "University of South Dakota-Sanford School of Medicine[Affiliation]"
Int J Mol Sci
January 2025
Division of Basic Biomedical Sciences, University of South Dakota Sanford School of Medicine, Vermillion, SD 57069, USA.
Brain-derived neurotropic factor (BDNF) is expressed by skeletal muscle as a myokine. Our previous work showed that the active precursor, proBDNF, is the predominant form of BDNF expressed in skeletal muscle, and that following skeletal muscle injury, proBDNF levels are significantly increased. However, the function of the muscle-derived proBDNF in injury-induced inflammation has yet to be fully understood.
View Article and Find Full Text PDFJ Behav Med
January 2025
Department of Counseling Psychology and Human Services, Prevention Science Institute, University of Oregon, Eugene, OR, USA.
Executive functioning (EF) has been linked to chronic disease risk in children. Health behaviors are thought to partially explain this association. The current cross-sectional study evaluated specific domains of EF and varied health behaviors in three pediatric life stages.
View Article and Find Full Text PDFAntibiotics (Basel)
December 2024
Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
: The development of broad-range polymerase chain reaction (BR-PCR) and next-generation sequencing techniques has significant implications for antimicrobial stewardship by increasing clinicians' ability to provide a tailored antimicrobial regimen. We sought to explore the clinical utility of BR-PCR testing and its impact on antimicrobial treatment among an adult cohort in a large hospital system. : We retrospectively evaluated samples that underwent BR-PCR testing between 2017 and 2021 and summarized their clinical characteristics and impact on antimicrobial therapy.
View Article and Find Full Text PDFJ Surg Case Rep
January 2025
Department of Plastic and Reconstructive Surgery, University of South Dakota Sanford School of Medicine, 1500 W. 22nd St. Suite 101, Sioux Falls, SD 57105, United States.
Achieving satisfactory nipple esthetics following skin-sparing or nipple-sparing mastectomy is an important element of ensuring positive patient outcomes. Several techniques used to reconstruct the nipple-areolar complex have been described in previous literature and have had success in securing good cosmetic outcomes. For patients with macrothelia, surgeons may employ a number of options in reducing nipple size.
View Article and Find Full Text PDFJ Rural Health
January 2025
Avera Research Institute, Avera McKennan Hospital, Sioux Falls, South Dakota, USA.
Purpose: The Environmental influences on Child Health Outcomes (ECHO) Cohort has enrolled over 60,000 children to examine how early environmental factors (broadly defined) are associated with key child health outcomes. The ECHO Cohort may be well-positioned to contribute to our understanding of rural environments and contexts, which has implications for rural health disparities research. The present study examined the outcome of child obesity to not only illustrate the suitability of ECHO Cohort data for these purposes but also determine how various definitions of rural and urban populations impact the presentation of findings and their interpretation.
View Article and Find Full Text PDFPLoS One
December 2024
Department of Medical Social Sciences, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America.
Early life environmental exposures, even those experienced before conception, can shape health and disease trajectories across the lifespan. Optimizing the detection of the constellation of exposure effects on a broad range of child health outcomes across development requires considerable sample size, transdisciplinary expertise, and developmentally sensitive and dimensional measurement. To address this, the National Institutes of Health (NIH) Environmental influences on Child Health Outcomes (ECHO) Cohort Study is an observational longitudinal pediatric cohort study.
View Article and Find Full Text PDFAm J Hum Genet
January 2025
Department of Genetics, CHU Sainte-Justine, Montréal, QC, Canada. Electronic address:
E3 ubiquitin ligases have been linked to developmental diseases including autism, Angelman syndrome (UBE3A), and Johanson-Blizzard syndrome (JBS) (UBR1). Here, we report variants in the E3 ligase UBR5 in 29 individuals presenting with a neurodevelopmental syndrome that includes developmental delay, autism, intellectual disability, epilepsy, movement disorders, and/or genital anomalies. Their phenotype is distinct from JBS due to the absence of exocrine pancreatic insufficiency and the presence of autism, epilepsy, and, in some probands, a movement disorder.
View Article and Find Full Text PDFAm J Prev Cardiol
March 2025
St. Elizabeth Healthcare, 20 Medical Village Drive, Suite 103, Edgewood, KY 41017, USA.
Background: Lipoprotein(a) [Lp(a)] is a low-density lipoprotein variant with atherogenic, thrombogenic, and pro-inflammatory properties that may have numerous pathologic effects, including dyslipidemia. Screening for Lp(a) is clinically significant, due to its causal role in atherosclerotic cardiovascular disease (ASCVD). Among clinicians, however, there remains a general lack of both clinical awareness of Lp(a) and adequate tools to track Lp(a) testing in patients.
View Article and Find Full Text PDFObjective: Learning environments affect the well-being of surgical faculty and trainees. Psychological safety (PS) has been linked with learning behaviors and aspects of well-being within medicine; however, given the unique challenges inherent to the surgical learning environment, there is a need to more closely examine these concepts for surgical faculty and trainees. The objective of this study is to examine the relationships between learning environment and PS, as well as PS and well-being with surgery.
View Article and Find Full Text PDFEpilepsia
December 2024
Division of Neurology, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Objective: SCN2A encodes the voltage-gated sodium (Na+) channel α subunit Na1.2, which is important for the generation and forward and back propagation of action potentials in neurons. Genetic variants in SCN2A are associated with a spectrum of neurodevelopmental disorders.
View Article and Find Full Text PDFJ Cataract Refract Surg
December 2024
University of South Dakota Sanford School of Medicine, Sioux Falls, SD, US.
Purpose: To evaluate visual and refractive outcomes in eyes with a history of radial keratotomy (RK) implanted with the second-generation light-adjustable lens (LAL).
Setting: Private practice, multiple locations.
Design: Retrospective, consecutive case series.
Pediatr Rev
December 2024
University of South Dakota Sanford School of Medicine, Vermillion, SD.
Emerg Med Clin North Am
February 2025
Department of Family Medicine, University of South Dakota Sanford School of Medicine, 1400 West 22nd Street, Sioux Falls, SD 57105, USA. Electronic address:
Cell Mol Bioeng
October 2024
Present Address: Cancer Biology and Immunotherapies Group, Sanford Research, Sioux Falls, SD USA.
Appl Neuropsychol Adult
November 2024
Department of Psychology, The Graduate Center, City University of New York, New York, NY, USA.
Trends Mol Med
October 2024
Division of Basic Biomedical Sciences, University of South Dakota Sanford School of Medicine, Vermillion, SD 57069, USA. Electronic address:
BMC Pediatr
October 2024
Department of Psychiatry, Columbia University Irving Medical Center, New York, NY, 10032, USA.
Circulation
October 2024
Division of Basic Biomedical Sciences, University of South Dakota Sanford School of Medicine, Vermillion (M.C., B.P., P.X., M.B., M.T.L., X.W.).
JBJS Case Connect
October 2024
University of South Dakota Sanford School of Medicine, Sioux Falls, South Dakota.
Front Neurol
September 2024
Centre for Neurology Studies, HealthTech Connex, Surrey, BC, Canada.
Clin Liver Dis
November 2024
Department of Internal Medicine, University of South Dakota Sanford School of Medicine, 1400 West 22nd Street, Sioux Falls, SD 57105, USA; Division of Hepatology, Avera McKennan Hospital & University Health Center, 1315 South Cliff Avenue, Suite 1200 Plaza 3, Sioux Falls, SD 57105, USA. Electronic address:
J Pediatr
September 2024
Stellenbosch University, Faculty of Medicine and Health Sciences, Department of Psychiatry, Cape Town, South Africa; Sanford Children's Genomic Medicine Consortium, Sanford Health; University of South Dakota Sanford School of Medicine, Department of Pediatrics, Sioux Falls, South Dakota.
J Surg Case Rep
September 2024
Department of Obstetrics and Gynecology, University of South Dakota Sanford School of Medicine, Sanford Health, Sioux Falls, SD 57105, United States.
Interv Neuroradiol
September 2024
Department of Radiology, Mayo Clinic, Rochester, MN, USA.