Urinary biomonitoring of exposure to glyphosate and its metabolite amino-methyl phosphonic acid among farmers and non-farmers in Morocco.

Glyphosate, a widely used herbicide in global agriculture, poses potential health risks due to environmental and dietary exposure. This study evaluated urinary concentrations of glyphosate and its metabolite, amino-methyl phosphonic acid (AMPA), among farmers and non-farmers in Morocco's Fez-Meknes region, using liquid chromatography-tandem mass spectrometry. Glyphosate was detected in 57.

Unraveling the hepatoprotective and anti-pancreatic cancer potential of : a comprehensive and in silico evidence.

Guss. () is a medicinal plant used for cancer treatment. However, these treatments may be associated with complications that need to be investigated.

Predictive Factors for Bowel Resection in Childhood Intussusception.

Background: Intestinal intussusception is the most common cause of intestinal obstruction in infants and children under 3 years of age. Any delay in diagnosis or management can lead to intestinal ischaemia and perforation. The aim of this study is to determine the sociodemographic and clinical risk factors associated with bowel resection in infants and children with intussusception.

Reassessment of Electrical and Dielectric Properties in the Borophosphate Glass System: A Promising Solid Electrolyte for High-Temperature Batteries.

This study investigates the conduction mechanism of ternary sodium borophosphate glass 30NaO-(70 - )BO-PO with 0 ≤ ≤ 35 mol % from a different perspective, focusing on previously unreported high-temperature electrical and dielectric properties for potential solid electrolytes in high-temperature batteries. The glass composition with BO/PO = 1 exhibits a conductivity of approximately 10 S/cm at 250 °C. Dielectric analysis supports this improved conduction, showing higher dielectric values and minimal energy dissipation during storage, indicating promising conductivity and favorable dielectric properties.

Detailed Phytochemical Composition, Cyto-/Hepatotoxicity, and Antioxidant/Anti-Inflammatory Profile of Moroccan Spices: A Study on Coriander, Caraway, and Mystical Cumin.

Coriander, caraway, and mystical cumin are famous for their aromatic properties and widely used in Moroccan cuisine. The nutritional/phytochemical composition of their seeds (used for food flavoring and preservation) were compared. Their antioxidant, anti-inflammatory, cytotoxic and hepatotoxic effects were also explored.

Benign and malignant prolapsed uterine tumors : 4 case reports of an extremely rare entities.

Prolapsed uterine tumors within the cervix or vagina, are attached to the uterine cavity by a soft tissue stalk. Malignant tumors and leiomyoma are the first diagnostic considerations for a prolapsed uterine mass with a visible stalk at MRI. This article describes 4 cases of patients who presented with large, necrotic prolapsed uterine tumors that were surgically confirmed and were diagnosed prospectively on the basis of MRI findings.

Chemical composition and potential antioxidant, anti-inflammatory, and analgesic efficacy of L.

This study aims to assess the chemical composition of the aqueous extract of L. leaves, as well as the potential of aqueous and hydroethanol extracts of the leaves and seeds as analgesic, anti--inflammatory, and antioxidant agents. The contents of phenolics and inorganic constituents were determined in seeds and leaves; antioxidant capacity was assessed by 3 complementary and diverse tests.

Multi-task approach based on combined CNN-transformer for efficient segmentation and classification of breast tumors in ultrasound images.

Accurate segmentation of breast ultrasound (BUS) images is crucial for early diagnosis and treatment of breast cancer. Further, the task of segmenting lesions in BUS images continues to pose significant challenges due to the limitations of convolutional neural networks (CNNs) in capturing long-range dependencies and obtaining global context information. Existing methods relying solely on CNNs have struggled to address these issues.

Antioxidant, Antimicrobial, and Insecticidal Properties of Chemically Characterized Essential Oils Extracted from : In Vitro and In Silico Analysis.

The present study aimed to explore the phytochemical profile, and evaluate the antioxidant, antimicrobial, and insecticidal properties, of Moroccan L. essential oil (ML-EO) using in vitro and in silico assays. Noteworthily, as chromatography (GC-MS/MS) revealed that ML-EO is majorly composed of piperitenone oxide (53.

Synthesis, crystal structure and Hirshfeld surface analysis of 1-(12-bromo-dodec-yl)indoline-2,3-dione.

In the title compound, CHBrNO, the indoline portion is almost planar and the 12-bromo-dodecyl chain adopts an all- conformation apart from the terminal C-C-C-Br fragment. A micellar-like structure is generated in the crystal by C-H⋯O hydrogen bonds and π-stacking inter-actions between indolinedione head groups and inter-calation of the 12-bromo-dodecyl tails. The Hirshfeld surface analysis of the crystal structure indicates that the most important contributions for the crystal packing are from H⋯H (58.

Crystal structure, Hirshfeld surface and crystal void analysis, inter-molecular inter-action energies, DFT calculations and energy frameworks of 2-benzo[][1,4]thia-zin-3(4)-one 1,1-dioxide.

In the title mol-ecule, CHNOS, the nitro-gen atom has a planar environment, and the thia-zine ring exhibits a screw-boat conformation. In the crystal, corrugated layers of mol-ecules parallel to the plane are formed by N-H⋯O and C-H⋯O hydrogen bonds together with C-H⋯π(ring) and S=O⋯π(ring) inter-actions. The layers are connected by additional C-H⋯O hydrogen bonds and π-stacking inter-actions.

Pharmacological activities of chemically characterized essential oils from (Forssk.).

The present work aimed at characterizing the phytochemical composition of essential oil (HTEO), assessing its antifungal activity against various fungal strains, evaluating its insecticidal and repulsive properties against , and determine its antioxidant capacity. To this end, Gas chromatography-mass spectrometry analysis detected 34 compounds in HTEO, with -Caryophyllene being the major constituent (36.94%).

Crystal structure, Hirshfeld surface analysis, inter-action energy and energy framework calculations, as well as density functional theory (DFT) com-putation, of methyl 2-oxo-1-(prop-2-yn-yl)-1,2-di-hydro-quinoline-4-carboxyl-ate.

In the title mol-ecule, CHNO, the di-hydro-quinoline core deviates slightly from planarity, indicated by the dihedral angle of 1.07 (3)° between the two six-membered rings. In the crystal, layers of mol-ecules almost parallel to the plane are formed by C-H⋯O hydro-gen bonds.

Chromone-isoxazole hybrids molecules: synthesis, spectroscopic, MEDT, ELF, antibacterial, ADME-Tox, molecular docking and MD simulation investigations.

A mechanistic study was performed within the molecular electron density theory at the B3LYP/6-311G (d,p) computational level to explain the regioselectivity observed. An electron localization function analysis was also performed, and the results confirm the zwitterionic-type (zw-type) mechanism of the cycloaddition reactions between nitrile oxide and alkylated 4-chromene-2-carboxylate derivatives and shed more light on the obtained regioselectivity experimentally. studies on the pharmacokinetics, ADME and toxicity tests of the compounds were also performed, and it was projected that compounds , , and are pharmacokinetic and have favorable ADME profiles.

Red-tailed hawk algorithm for numerical optimization and real-world problems.

This study suggests a new nature-inspired metaheuristic optimization algorithm called the red-tailed hawk algorithm (RTH). As a predator, the red-tailed hawk has a hunting strategy from detecting the prey until the swoop stage. There are three stages during the hunting process.

Study of the Phytochemical Composition, Antioxidant Properties, and In Vitro Anti-Diabetic Efficacy of Extracts.

In this study, a comparison was made of the chemical makeup of different extracts obtained from , a type of red seaweed that was gathered from the Nador lagoon situated in the northern part of Morocco. Additionally, their anti-diabetic and antioxidant properties were investigated. The application of GC-MS technology to analyze the fatty acid content of the samples revealed that linoleic acid and eicosenoic acid were the most abundant unsaturated fatty acids across all samples, with palmitic acid and oleic acid following in frequency.

Extracts of (Delile) Vis Exhibit In Vivo Wound Healing, Anti-Inflammatory and Analgesic Activities, and Other In Vitro Therapeutic Effects.

The plant (Delile) () has many uses in traditional pharmacology. Aqueous (BCAE) and ethanolic extracts (BCEE) obtained from the aerial parts can be used as an alternative to some synthetic drugs. In vitro, DPPH, FRAP and TAC are three tests used to measure antioxidant efficacy.

Coordinatively Cross-Linked Binders for Silicon-Based Electrodes for Li-Ion Batteries: Beneficial Impact on Mechanical Properties and Electrochemical Performance.

A simple and versatile preparation of Zn(II)-poly(carboxylates) reticulated binders by the addition of Zn(II) precursors (ZnSO, ZnO, or Zn(NO)) into a preoptimized poly(carboxylic acids) binder solution is proposed. These binders lead systematically to a significantly improved electrochemical performance when used for the formulation of silicon-based negative electrodes. The formation of carboxylate-Zn(II) coordination bonds formation is investigated by rheology and FTIR and NMR spectroscopies.

Phenolic Composition, Wound Healing, Antinociceptive, and Anticancer Effects of Extracts.

(Guss.) is an important medicinal plant widely used in Morocco for various traditional purposes. Our work aimed to evaluate the phenolic composition, wound healing, antinociceptive, and anticancer activities of extracts.