1 results match your criteria: "University of Shanghai for Science and Technology Shanghai 200093 China yqmiao@usst.edu.cn ouyangrz@usst.edu.cn.[Affiliation]"
Rapid electrochemical detection of MiRNA-21 facilitated by the excellent catalytic ability of Pt@CeO nanospheres.
RSC Adv
April 2022
Institute of Bismuth and Rhenium Science, School of Materials and Chemistry, University of Shanghai for Science and Technology Shanghai 200093 China
Pt@CeO nanospheres (NSs) were first synthesized by simply mixing Ce(NO) and KPtCl under the protection of pure argon at 70 °C for 1 h, which exhibited excellent catalytic ability toward hydrogen peroxide (HO). An electrochemical biosensor was successfully developed using Pt@CeO NSs as a capture probe for the ultra-sensitive and fast detection of miRNA-21, a new type of biomarker for disease diagnostics, especially for cancer. During the step-by-step construction process of the RNA sensor, Pt@CeO NSs were functionalized with streptavidin (SA) to obtain SA-Pt@CeO NSs through amide bonds.
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