α-FeO and polypyrrole impregnated alginate/gelatin nanocatalysts for the reduction of azo dyes and persistent organic pollutants.

Herein, we propose magnetic nanocomposites as a powerful new catalyst for organic pollutant reduction. Polypyrrole (PPy) was synthesized in situ within the semi-interpenetrating alginate (Alg)/gelatin (Ge) network in presence of α-FeO as encapsulating matrix and inorganic filler, respectively. The polymeric matrix can act as bifunctional agent such as a binder and stabilizer to improve nanocatalyst stability while preserving their catalytic/magnetic performances.

Dichloroacetate and chloroquine in combination with arsenite suppress ROS-induced oral squamous cell carcinoma (OSCC) development and improve BALB/c mice survival.

Oral squamous cell carcinoma (OSCC) is a disabling tumor with poor response to chemotherapy. Here, we sought to explore a new chemotherapeutic approach based on a combined induction of cytotoxic ROS and targeting of autophagy and aerobic glycolysis as central contributors to OSCC carcinogenesis and chemoresistance. To this end, tongue OSCC was generated in BALB/c mice using 4NQO.

Highlighting chromosomal rearrangements of five species of Galliformes (Domestic fowl, Common and Japanese quail, Barbary and Chukar partridge) and the Houbara bustard, an endangered Otidiformes: banding cytogenetic is a powerful tool.

Birds are one of the most diverse groups among terrestrial vertebrates. They evolved from theropod dinosaurs, are closely related to the sauropsid group and separated from crocodiles about 240 million years ago. According to the IUCN, 12% of bird populations are threatened with potential extinction.

Isolation and Characterization of Novel Cellulose Micro/Nanofibers from Through a Chemo-Mechanical Process.

Recent studies have focused on the development of bio-based products from sustainable resources using green extraction approaches, especially nanocellulose, an emerging nanoparticle with impressive properties and multiple applications. Despite the various sources of cellulose nanofibers, the search for alternative resources that replace wood, such as , a fast-growing Mediterranean plant, is crucial. It has not been previously investigated as a potential source of nanocellulose.

Performance of artificial intelligence model (LSTM model) for estimating and predicting water quality index for irrigation purposes in order to improve agricultural production.

The primary goal of this study is to predict the current and future water quality index for irrigation (WQII) of the western Mitidja alluvial aquifer in northern Algeria. The modified WQII was used to evaluate groundwater suitability for irrigation through geographic information system (GIS) techniques. Additionally, a long short-term memory (LSTM) model was employed to calculate the WQII and map future groundwater quality, considering factors like overexploitation, anthropogenic pollution, and climate change.

Silver decorated zeolite embedded in bionanocomposite hydrogels based on cross-linked carboxymethyl cellulose for excellent catalytic hydrogenation of azo dyes.

Herein, bionanocomposite beads based on Carboxymethyl cellulose/Dextrant sulfate (CMC/DS) embedding silver nanoparticle-functionalized zeolite (AgZ) were developed and proposed as catalysts for catalytic hydrogenation of Direct Red 16 (DR16) azo dye under different experimental parameters. The obtained results showed that AgZ incorporation into the polymer matrix produced highly porous structures with improved thermal stability. For antibacterial application, it was shown that the engineered bionanocomposites were effective against all tested bacteria.

Low-dose dimethylfumarate attenuates colitis-associated cancer in mice through M2 macrophage polarization and blocking oxidative stress.

Colitis-associated cancer (CAC) is an aggressive subtype of colorectal cancer that can develop in ulcerative colitis patients and is driven by chronic inflammation and oxidative stress. Current chemotherapy for CAC, based on 5-fluorouracil and oxalipltin, is not fully effective and displays severe side effects, prompting the search for alternative therapies. Dimethylfumarate (DMF), an activator of the nuclear factor erythroid 2-related factor 2 (NRF2), is a potent antioxidant and immunomodelatrory drug used in the treatment of multiple sclerosis and showed a strong anti-inflammatory effect on experimental colitis.

Exploring the relationship between oxidative stress status and inflammatory markers during primary Sjögren's syndrome: A new approach for patient monitoring.

Introduction: Primary Sjögren's syndrome (pSS) is a chronic inflammatory disease primarily affects exocrine glands dysfunction. Oxidative stress (OS) is a phenomenon occurring as a result of an imbalance between the generation of free radicals and antioxidant defense system. Hence, we aimed to establish the status of OS and inflammatory response according to the pSS disease activity index.

Neuroinflammation, neurodegeneration and alteration of spatial memory in BALB/c mice through ampicillin-induced gut dysbiosis; NOS2 and NFL involvement in a microbiota-gut-brain axis model.

We aimed to investigate ampicillin (AMP) mechanisms in microbiota-gut-brain axis. We evaluated its effect on two gut and brain regions and behavioral performances. We administred AMP (1 g/l) to BALB/c mice for 21 days.

Metabolic disorders induced the changes in the expressions of TNFα, E-cadherin and ultrastructural alteration of liver cells in a typical animal model of type 2 diabetes: Psammomys obesus.

By using a unique animal model of type 2 diabetes mellitus, Psammomys obesus induced by a high-calorie diet (HCD) for nine months, we showed for the first time, in the liver, the impact of inflammation on the remodeling of intercellular junction molecules E-cadherins during the progression of steatohepatitis. Under the effect of HCD, the expressions of immunohistochemical markers, Tumor Necrosis Factor alpha (TNFα) and E-cadherins were inversely correlated. Ultrastructural examination revealed the involvement of destabilization and loss of E-cadherins in the process of hepatic pathogenesis.

High-temperature CO sorption over LiSiO synthesized from diatomite: study of sorption heat and isotherm modeling.

The LiSiO seems to be an excellent sorbent for CO capture at post-combustion. Our work contributes to understanding the effect of the natural Algerian diatomite as a source of SiO in the synthesis of LiSiO for CO capture at high temperature. For this purpose, we use various molar % (stoichiometric and excess) of calcined natural diatomite and pure SiO.

Conception of pH-sensitive calcium alginate/poly vinyl alcohol hydrogel beads for controlled oral curcumin delivery systems. Antibacterial and antioxidant properties.

Curcumin, a bioactive compound derived from the rhizome of Curcuma longa, has gained widespread attention for its potential therapeutic properties, including anti-inflammatory, antioxidant and anticancer effects. However, its poor aqueous solubility, instability and limited bioavailability have hindered its clinical applications. New beads formulations based on sodium alginate biopolymer (SA) and poly vinyl alcohol (PVA) were successfully prepared and evaluated as a potential drug vehicle for extended release of curcumin (Cur).

Sponge-like biodegradable polypyrrole-modified biopolymers for selective adsorption of basic red 46 and crystal violet dyes from single and binary component systems.

Recently, several researchers have been trying to reduce the ecological effects of water pollution by considering the use of biodegradable materials that prevent the generation of secondary pollution in our environment and enable water reuse. Here, new biodegradable hydrogels based on alginate (Alg), gelatin (Gel) and polypyrrole (PPy) were successfully implemented to remove two known highly toxic cationic dyes from wastewater. The design process was performed in two steps: in-situ polymerization of polypyrrole within the Alg/Gel mixture, followed by hydrogel formation.

The effects of 20-hydroxyecdysone on nuclear shape, heterochromatin quantity and gray-level co-occurrence matrix texture analysis of adrenal zona fasciculata cells in an obese gerbil (Gerbillus tarabuli) model for metabolic syndrome: a correlational study.

The aim of this study was to reveal the effects of obesity and phytotherapy with 20-hydroxyecdysone (20E) on the nuclei of adrenal zona fasciculata (ZF) in the gerbil Gerbillus tarabuli by analyzing nuclear shape and gray-level co-occurrence matrix (GLCM) texture characteristics and by quantifying heterochromatin. Twelve gerbils were divided into three groups: control (C), HC and HC-20E (animals receiving a high-calorie-diet without or with a supplement of 20E, respectively). The adrenals were removed and fixed for histological and statistical analysis.

Immunomodulatory effect of vitamin D supplementation on Behçet's disease patients: effect on nitric oxide and Th17/Treg cytokines production.

Introduction: In the last decade, an immuno-modulatory effect of vitamin D supplementation have emerged as a potential therapeutic approach for some inflammatory and autoimmune diseases. As previously reported, vitamin D deficiency was strongly linked to several diseases as Behçet's disease (BD). BD is a chronic systemic inflammatory disorder with autoimmunity, genetic and environmental factors involvement.

20-Hydroxyecdysone bioavailability and pharmacokinetics in Gerbillus tarabuli, a gerbil model for metabolic syndrome studies.

Phytoecdysteroids are active natural compounds that have demonstrated many beneficial pharmacological effects on mammals, including Humans. 20-Hydroxyecdysone (20E) is the major phytoecdysteroid present in plants, and gerbils are particularly good responders to the addition of 20E to their diet. We have examined the oral bioavailability of 20E in the desert gerbil, Gerbillus tarabuli.

WebRTC-based MOSR remote control of mobile manipulators.

This article describes a contribution to the field of telerobotics via the Internet through the development of a web-based platform allowing the remote control of robots by multiple users, simultaneously. It also deals with minimizing the execution times of tasks by reducing connection and interaction delays. For this purpose, the () technology is utilized.

Cross-linked CMC/Gelatin bio-nanocomposite films with organoclay, red cabbage anthocyanins and pistacia leaves extract as active intelligent food packaging: colorimetric pH indication, antimicrobial/antioxidant properties, and shrimp spoilage tests.

Multifunctional food packaging films were produced from crosslinked carboxymethyl cellulose/gelatin (CMC/Ge) bio-nanocomposites incorporated with Ge-montmorillonite (OM) nanofiller, anthocyanins (ATH) from red cabbage as colorimetric pH-indicator, and pistacia leaves extract (PE) as active agent. The influence of additives on the structural, physical, and functional properties of the films was investigated. The results showed that ATH and PE caused color alteration and reduced transparency.

A comparative study of heterogeneous and homogeneous ensemble approaches for landslide susceptibility assessment in the Djebahia region, Algeria.

This study aims to compare the performance of ensembles according to their inherent diversity in the context of landslide susceptibility assessment. Heterogeneous and homogeneous ensemble types can be distinguished; four ensembles of each approach were implemented in the Djebahia region. The heterogeneous ensembles include stacking (ST), voting (VO), weighting (WE), and a new approach in landslide assessment called meta-dynamic ensemble selection (DES), while the homogeneous ensembles include AdaBoost (ADA), bagging (BG), random forest (RF), and random subspace (RSS).

Nitric Oxide, Neutrophil/Lymphocyte, and Platelet/Lymphocyte Ratios as Promising Inflammatory Biomarkers in Complicated Crohn's Disease: Outcomes of Corticosteroids and Anti-TNF-α Therapies.

Crohn's disease (CD) is a relapsing-remitting inflammatory bowel disease with a progressive course. The aim of our study was to evaluate the relationship between nitric oxide (NO), pro-inflammatory cytokines, and blood count-based ratios in patients with complicated Crohn's disease as well as the outcome of corticosteroid or anti-TNF-α therapy. In this context, we evaluated the NLR as the ratio of neutrophils count to lymphocytes count, PLR as the ratio of platelets count to lymphocytes count, and MLR as the ratio of monocytes count to lymphocytes count in patients and controls.

New combined DT-CWT and HOG descriptor for static and dynamic hand gesture recognition.

In recent years, researchers have been focusing on developing Human-Computer Interfaces that are fast, intuitive, and allow direct interaction with the computing environment. One of the most natural ways of communication is hand gestures. In this context, many systems were developed to recognize hand gestures using numerous vision-based techniques, these systems are highly affected by acquisition constraints, such as resolution, noise, lighting condition, hand shape, and pose.

Assessment of soil contamination by heavy metals and arsenic in Tamesguida abandoned copper mine area, Médéa, Algeria.

Heavy metal and arsenic pollution of soil remains a serious environmental problem long after mining operations have ended. For instance, the Tamesguida copper mine located in north-central Algeria has been abandoned for several decades without restoration or even an environmental impact assessment. Therefore, soils were collected from several locations in the vicinity of the old mine and tailings and analyzed for their Cu, Cr, As, Pb, Ni, Zn, and Fe rates to gauge the scope of the soil contamination caused by these elements, and assessing their origin and their dispersion in the mine area.

Preparation, characterization, immobilization, and molecular docking analysis of a novel detergent-stable subtilisin-like serine protease from Streptomyces mutabilis strain TN-X30.

We recently described the production of a detergent-biocompatible crude protease from Streptomyces mutabilis strain TN-X30. Here, we describe the purification, characterization, and immobilization of the serine alkaline protease (named SPSM), as well as the cloning, sequencing, and over-expression of its corresponding gene (spSM). Pure enzyme was obtained after ammonium sulphate precipitation followed by heat-treatment and Sephacryl® S-200 column purification.