The extent of the hip bone sexual dimorphism in two Italian coeval modern skeletal samples.

The rate of sexual dimorphism in the human hip bone is primarily due to the structural demands of childbirth. Genetic, environmental, and socio-cultural factors can also influence pelvic shape variations across populations. This study examines intra-population sex variation within the Italian population based on regional differences of 280 coxal bones from two documented human osteological collections (Bologna and Sassari) coming from different geographical areas, the northern continental and island regions.

Ultrasound guided procedures in the head and neck: a clinician centered model.

Background: US guided sampling is a validated diagnostic approach for non-thyroid deep head and neck masses.

Aim: To describe the setting of a clinician-driven Lump Clinic and analyze a monoinstitutional 7-year database of 849 patients undergoing US-guided sampling.

Methods: FNA with Rapid OnSite Evalutation (ROSE) was the first diagnostic step.

Incidence of hospital-acquired infections due to carbapenem-resistant Enterobacterales and Pseudomonas aeruginosa in critically ill patients in Italy: a multicentre prospective cohort study.

Background: Carbapenem-Resistant Gram-Negative Bacteria, including Carbapenem-Resistant Enterobacterales (CRE) and Carbapenem-Resistant Pseudomonas aeruginosa (CRPA), are common causes of infections in intensive care units (ICUs) in Italy.

Objective: This prospective observational study evaluated the epidemiology, management, microbiological characterization, and outcomes of hospital-acquired CRE or CRPA infections treated in selected ICUs in Italy.

Methods: The study included patients with hospital-acquired infections due to CRE and CRPA treated in 20 ICUs from June 2021 to February 2023.

Enhancing AI Chatbot Responses in Health Care: The SMART Prompt Structure in Head and Neck Surgery.

Objective: This study aims to evaluate the impact of prompt construction on the quality of artificial intelligence (AI) chatbot responses in the context of head and neck surgery.

Study Design: Observational and evaluative study.

Setting: An international collaboration involving 16 researchers from 11 European centers specializing in head and neck surgery.

A Long-term Evaluation: Deep Plane versus High SMAS Face Lift.

In the last few years, the Deep Plane Face Lift (DPFL) has gained great popularity among plastic surgeons, even if its origins are traced back to the 1970s. Certainly, it could have some advantages but based on our experience, it can reveal some unpleasant features in the long term. For this reason, the senior authors have adopted the high superficial musculoaponeurotic system (SMAS) Face Lift for many years in their surgical practice.

Hydrolysis, Ligand Exchange, and Redox Properties of Vanadium Compounds: Implications of Solution Transformation on Biological, Therapeutic, and Environmental Applications.

Vanadium is a transition metal with important industrial, technological, biological, and biomedical applications widespread in the environment and in living beings. The different reactions that vanadium compounds (VCs) undergo in the presence of proteins, nucleic acids, lipids and metabolites under mild physiological conditions are reviewed. In the environment vanadium is present naturally or through anthropogenic sources, the latter having an environmental impact caused by the dispersion of VCs in the atmosphere and aquifers.

Adjusting the Yo-Yo IRT-1 equation to estimate VO2max of sub-elite football referees: a gender-comparative study.

Background: To gain optimal positioning to make sure the game laws are applied in uniform way, the performance of field referee must be periodically evaluated to have constantly adequate training during a match and during the competitive season. Considering that field Yo-Yo Intermittent Recovery Test-Level 1 is frequently employed in elite team sport players to estimate maximal oxygen uptake (VO2max) in field settings, the aim of this cross-sectional, gender-comparative study was to develop a new adjusted Yo-Yo-1 equation for estimating VO2max in football referees.

Methods: During off-season, 20 male (21.

MOG antibody-associated disease epidemiology in Olmsted County, USA, and Martinique.

Objectives: To report myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) epidemiology in two American regions using 2023 diagnostic criteria.

Patients And Methods: We compared age- and sex-adjusted incidence and prevalence of MOGAD per 2023 diagnostic criteria in Olmsted County (Minnesota [USA]) and Martinique (Caribbean [FR]) (01/01/2003-12/31/2018, prevalence day) using Poisson regression. Archived sera in 68-85% were available for MOG-IgG testing by live cell-based assay at Mayo Clinic.

Impact of optimal secondary cytoreductive surgery on survival outcomes in women with recurrent endometrial carcinoma: A systematic review and meta-analysis.

Background: Management of recurrent endometrial carcinoma (EC) represents a challenge. Although a complete resection of visible disease at secondary surgery (R0) is recommended, the impact of R0 on survival outcomes is unclear and pooled data are lacking.

Objective: To quantitatively assess the impact of R0 on survival outcomes in women with EC recurrence.

Safety and efficacy of a light antithrombotic regimen after left atrial appendage occlusion: Insights from the LOGIC (left atrial appendage occlusion in patients with gastrointestinal or IntraCranial bleeding) international multicenter registry.

Background: Antithrombotic therapy (AT) after left atrial appendage occlusion (LAAO) in patients with non-valvular atrial fibrillation (NVAF) has the purpose of preventing device related thrombosis (DRT), avoiding embolic events; nevertheless, the correct antithrombotic regimen after LAAO is still under debate.

Aims: Aim of this substudy of the observational LOGIC registry was to describe the efficacy and safety of a light antithrombotic regimen, comprising single antiplatelet therapy or none, compared to a standard antithrombotic regimen, after a successful LAAO.

Methods: Patients with NVAF that underwent LAAO were previously included in the LOGIC registry.

Large clones of Clonal Hematopoiesis affect outcome in Mantle Cell Lymphoma: Results from The FIL MCL0208 Clinical Trial.

Although recent evidence suggests that myeloid clonal hematopoiesis (M-CH) may influence lymphoma clinical outcome, its impact in mantle cell lymphoma (MCL) remains unclear. Here, we report a comprehensive NGS-based analysis of the M-CH mutational landscape at baseline and follow-up in patients enrolled in the Fondazione Italiana Linfomi (FIL) MCL0208 phase 3 trial (NCT02354313), evaluating lenalidomide maintenance versus observation after chemoimmunotherapy and autologous stem cell transplantation (ASCT) in untreated young MCL patients. Overall, 254/300 (85%) enrolled patients (median age 57 years [32-66]) had a baseline sample available for CH analysis.

Hyaluronic Acid-Based Hybrid Nanoparticles as Promising Carriers for the Intranasal Administration of Dimethyl Fumarate.

Purpose: Dimethyl fumarate (DMF), the first-line oral therapy for relapsing-remitting multiple sclerosis, is rapidly metabolized into monomethyl fumarate. The DMF oral administration provokes gastrointestinal discomfort causing treatment withdrawal. The present study aimed to develop an innovative formulation for DMF nasal administration.

Evaluation of Negative Pressure Wound Therapy dressing in the management of mommy makeover surgery wounds.

Background: This investigation explores the potential impact of Negative Pressure Wound Therapy (NPWT) dressing on mommy makeover surgical wounds. The focus is on optimizing the healing process and post-surgical care to mitigate complications like wound dehiscence, seroma, and hematoma.

Patients And Methods: A prospective study spanned from October 2015 to April 2022, involving 40 patients undergoing mommy makeover surgery for aesthetic purposes.

Brain dynamics and personality: a preliminary study.

Personality can be considered a system characterized by complex dynamics that are extremely adaptive depending on continuous interactions with the environment and situations. The present preliminary study explores the dynamic interplay between brain flexibility and personality by taking the dynamic approach to personality into account, thereby drawing from Cloninger's psychobiological model. 46 healthy individuals were recruited, and their brain dynamics were assessed using magnetoencephalography (MEG) during the resting state.

Biobased vitrimers: towards sustainability and circularity.

In polymer science and technology, the distinction between thermoplastic and thermosetting materials has always been sharp, clear, and well-documented: indeed, the former can theoretically be reprocessed a potentially infinite number of times by heating, forming, and subsequent cooling. This cannot be done in the case of thermosetting polymers due to the presence of cross-links that covalently bind the macromolecular chains, giving rise to insoluble and infusible polymeric networks. In 2011, the discovery of vitrimers revolutionized the classification mentioned above, demonstrating the possibility of using new materials that consist of covalent adaptable networks (CANs): this way, they can change their topology through thermally-activated bond-exchange reactions.

Insights into the separation, enantioseparation and recognition mechanisms of methamphetamine isotopologues on achiral and polysaccharide-based chiral columns in high-performance liquid chromatography.

Background: Isotopologues resulting from the labelling of molecules with deuterium have attracted interest due to the isotope effect observed in chemistry and biosciences. Isotope effect may also play out in noncovalent interactions and mechanisms leading to intermolecular recognition. In chromatography, differences in retention time between isotopologues, as well as between isotopomers have been observed resulting in two different elution sequences (isotope effects): the normal isotope effect when heavier isotopologues retain longer than lighter analogues, and the inverse isotope effect featuring the opposite elution order.

Seasonal variation in myasthenia gravis incidence.

Introduction: Environmental factors may contribute to myasthenia gravis (MG) development, sometimes with seasonal patterns of exposure. However, whether seasonality has an impact on MG incidence remains unclear. We aimed to investigate the association between seasonality and MG onset.

3-Step Combined Technique for Correction of Involutional Lower Eyelid Ectropion: A Case Series.

Involutional lower eyelid ectropion is a common disorder of the elderly population. Several surgical approaches have been described in the literature to address the multifactorial nature of this condition, each targeting different factors contributing to its development. Nevertheless, no single procedure has proven to be superior to the others.

Perception of Sour Taste in Subjects with Olfactory Deficits: Role of Myrtle Aromatization.

Background: Sour taste is associated with acid-base homeostasis, which is critical to cell metabolism and health conditions. Vinegar, which contains acetic acid as the main component, is a sour food considered the second most common condiment in Italy.

Objectives: The aim of the study was to assess differences in sourness perception in subjects with olfactory deficits compared to controls and evaluate myrtle aromatization's potential effect in modulating sourness perception in subjects with hyposmia.

Extraction and Characterization of Artichoke ( L.) Solid Waste from the Industrial Processing of Fresh-Cut Products for Nutraceutical Use.

Artichoke ( L.) is an herbaceous perennial plant from the Mediterranean Basin, cultivated as a poly-annual crop in different countries. Artichoke produces a considerable amount of waste at the end of the harvesting season in the field (5.

The carbon cost of impaired welfare on sheep farms.

In the face of global climate threats, farm and land-management decisions must balance climate concerns with profitability, animal welfare, and ecosystem health. However, few comprehensive studies have quantified the relationship between animal welfare and greenhouse gas (GHG) emissions, and no study focuses specifically on sheep farms. The present study aims to quantify the effects of impaired welfare on GHG emissions for common welfare challenges faced in UK lowland (L) and hill (H) sheep farming systems.

Restrictive Versus Liberal Transfusion in Symptomatic Coronary Artery Disease and Myocardial Infarction: A Meta-Analysis of Randomized Controlled Trials.

Background: In patients with coronary artery disease (CAD) and/or myocardial infarction (MI), anemia is associated with an increased risk of adverse cardiovascular (CV) outcomes. Transfusion goals in such patients remain unclear.

Study Question: A meta-analysis of the available randomized controlled trials (RCTs) was conducted comparing restrictive and liberal transfusion strategies in patients with symptomatic CAD/MI.

Detection of Echinococcus spp. and other taeniid species in lettuces and berries: Two international multicenter studies from the MEmE project.

Cystic and alveolar echinococcosis are severe zoonotic diseases characterized by long asymptomatic periods lasting months or years. Viable Echinococcus spp. eggs released into the environment through the feces of canids can infect humans through accidental ingestion via hand-to-mouth contact or consumption of contaminated food or water.

The Influence of Resistance Training on Joint Flexibility in Healthy Adults: A Systematic Review, Meta-analysis, and Meta-regression.

Favro, F, Roma, E, Gobbo, S, Bullo, V, Di Blasio, A, Cugusi, L, and Bergamin, M. The influence of resistance training on joint flexibility in healthy adults: A systematic review, meta-analysis, and meta-regression. J Strength Cond Res XX(X): 000-000, 2024-Joint flexibility is a key component of physical fitness.