Identification of the Novel HLA-DRB3*02:185 Allele by Next-Generation Sequencing in a Post-Transplant Renal Patient.

The novel allele HLA-DRB3*02:185 differs from HLA-DRB3*02:02:01:02 by one nucleotide substitution in codon 191 of exon 4.

Intrinsic and environmental drivers of pairwise cohesion in wild Canis social groups.

Animals within social groups respond to costs and benefits of sociality by adjusting the proportion of time they spend in close proximity to other individuals in the group (cohesion). Variation in cohesion between individuals, in turn, shapes important group-level processes such as subgroup formation and fission-fusion dynamics. Although critical to animal sociality, a comprehensive understanding of the factors influencing cohesion remains a gap in our knowledge of cooperative behavior in animals.

Mixed strongyle parasite infections vary across host age and space in a population of feral horses.

Identifying factors that drive among-individual variation in mixed parasitic infections is fundamental to understanding the ecology and evolution of host–parasite interactions. However, a lack of non-invasive diagnostic tools to quantify mixed infections has restricted their investigation for host populations in the wild. This study applied DNA metabarcoding on parasite larvae cultured from faecal samples to characterize mixed strongyle infections of 320 feral horses on Sable Island, Nova Scotia, Canada, in 2014 to test for the influence of host (age, sex and reproductive/social status) and environmental (location, local density and social group membership) factors on variation.

Enhancing, Targeting, and Improving Dental Trauma Education: Engaging Generations Y and Z.

Dental trauma is highly prevalent, involving 25% of school-age children and about 12.5% of the general population of the world. Due to the young age of the patients that are usually involved in dental trauma, there are tooth-related complicating factors, such as open apices, thin dentinal walls, and unfavorable crown-to-root ratio, as well as patient-related factors, such as anxiety and cooperation, and other challenges related to the complex diagnosis and treatment.

Five years of competency-based medical education in Canadian urology: A national survey of senior resident and faculty satisfaction and perspectives.

Introduction: In 2018, competency-based medical education (CBME) was introduced to Canadian urology residency training. We examined learner and faculty experiences with CBME five years post-implementation.

Methods: Two online surveys were developed from a scoping review of CBME literature and expert consultation.

Exercise as a Therapeutic Intervention in Multiple Sclerosis.

The role of exercise as a therapeutic intervention in multiple sclerosis (MS) has shifted over time. Early views surrounding exercise in MS advocated for caution against participation. With increasing evidence, perspectives shifted to promote exercise as a therapeutic approach for symptom management.

Characterization and effects of heat treatments on antinutritional components and enzyme activities in sainfoin (Onobrychis viciifolia L.) seeds: A high-protein alternative plant-based food source.

The aim of this study was to characterize and explore the food potential of sainfoin seeds, which are primarily used in their green plant form to feed livestock. A detailed assessment of the seed's proximate composition, enzyme activity levels, and antinutrient content was performed. The seeds were then subjected to infrared, hot air, and blanching treatments to examine how these processing methods affect enzyme activities and antinutrients.

Development of an indigestible dietary protein index to investigate the effects of dietary protein content in postweaned pigs.

Proteolytic fermentation induces negative effects on gut health and function, which may affect pig performance. The objective was to conduct a meta-analysis to develop an index of dietary indigestible dietary protein (IDP) to investigate growth performance outcomes of mixed-sex weanling pigs (average body weight of 7.59 kg).

Targeted syndromic next-generation sequencing panel for simultaneous detection of pathogens associated with bovine reproductive failure.

Bovine reproductive failure, which includes infertility, abortion, and stillbirth in cattle, leads to significant economic losses for beef and milk producers. Diagnosing the infectious causes of bovine reproductive failure is challenging as there are multiple pathogens associated with it. The traditional stepwise approach to diagnostic testing is time-consuming and can cause significant delays.

Triticain alpha represents the major active papain-like cysteine protease in naturally senescing and ozone-treated leaves of wheat.

Current background tropospheric ozone (O) concentrations have significant adverse effects on wheat. O generally induces oxidative damages and premature leaf senescence leading to important yield losses. As leaf protein degradation and recycling is involved in both maintaining cell longevity during abiotic stresses and performing efficient nitrogen remobilization during senescence, we aimed to identify proteases involved in acidic endoproteolytic activities during natural and O-induced leaf senescence in wheat.

SCAI Expert Consensus Statement on the Management of Patients With STEMI Referred for Primary PCI.

ST-elevation myocardial infarction (STEMI) remains a leading cause of morbidity and mortality in the United States. Timely reperfusion with primary percutaneous coronary intervention is associated with improved outcomes. The Society for Cardiovascular Angiography & Interventions puts forth this expert consensus document regarding best practices for cardiac catheterization laboratory team readiness, arterial access with an algorithm to help determine proper arterial access in STEMI, and diagnostic angiography.

A revision and addition to Zopheridae (Coleoptera: Tenebrionoidea) in Baltic amber: possible connections between modern Holarctic distributions and Eocene 'amber forests'.

One new extinct genus and six new extinct species of Zopheridae are described and illustrated from Eocene Baltic amber: Usechus andrushchenkoi Alekseev et Bukejs sp. nov., Coxelus carstengroehni Alekseev et Bukejs sp.

Building a community of practice to address alcohol harms in Canada: Experience from the Canadian Alcohol Policy Evaluation project.

Setting: Alcohol is a major cause of health and social costs and harms in Canada. While research and awareness of harms caused by alcohol are on the rise, few transdisciplinary platforms exist that are committed to facilitating bold alcohol policy change to reduce health inequities and improve lives.

Intervention: In response to feedback heard during engagement for the Canadian Alcohol Policy Evaluation project, an alcohol policy-focused community of practice (CoP) was launched in January 2022.

Freeze-drying synthesis of mesoporous magnetic grafted chitosan/calcium oxide nanoparticle for remazol brilliant blue dye removal: A statistical optimization.

Herein, a mesoporous magnetic chitosan-salicylaldehyde/calcium oxide nanoparticle (CS-SL/CaO/FeO) biocomposite adsorbent that was prepared via freeze-drying. The CS-SL/CaO/FeO was utilized for the adsorption of ramazol brilliant blue (RBB) dye from aqueous solution. The physicochemical properties of the CS-SL/CaO/FeO were evaluated using diverse characterization techniques, including BET, XRD, FTIR, FESEM-EDX, CHNS, and pH.

Experiences and Perspectives of Canadian Dietetic Educators Regarding Food Literacy and Its Incorporation Into Undergraduate Dietetics Programs.

Objective: To explore the experiences and perspectives of Canadian dietetic educators regarding food literacy and its incorporation into accredited undergraduate food and nutrition programs.

Design: Semistructured qualitative interviews.

Setting: Canada.

Human trafficking screening in Saskatoon Emergency Departments: What can be learned from high-risk patient presentations?

Objective: Studies have shown that Emergency Department physicians have little to no training in recognizing and supporting victims of human trafficking despite being uniquely situated to identify and intervene on behalf of these patients. We assessed if screening for human trafficking was being completed by emergency physicians in three Saskatoon emergency departments.

Methods: We performed a retrospective chart review of patients presenting to three Saskatoon emergency departments deemed to potentially be at risk of human trafficking, based on discharge diagnosis.

Payment model impact on the resilience of rural communities: Exploratory study.

Objective: To explore rural physician perspectives on how remuneration impacted their experiences of contributing to community resilience during the COVID-19 pandemic.

Design: Exploratory, qualitative subanalysis.

Setting: Twenty-two rural communities in 4 Canadian provinces.