4,623 results match your criteria: "University of Sao Paulo-USP[Affiliation]"

This cross-sectional observational study aimed to investigate the relationship between satisfaction with facial appearance among young women, as measured by the FACE-Q tool, and facial asymmetry quantified through stereophotogrammetry. A total of 50 women aged 18 to 30 years with a normal body mass index were recruited for the study. Participants were categorized as either symmetrical or asymmetrical based on facial asymmetry assessments obtained through clinical examination and stereophotogrammetry using the Vectra M3 system.

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Physiological and hematological traits and productive performance of Spanish Majorera and Palmera goats reared on the Island of Tenerife-Spain were assessed. 50 adult, clinically healthy, multiparous female goats were studied for 18 months. The data were analyzed in a two (breeds) x four (season) factorial scheme.

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Background: Recent evidence indicates that statins have anti-inflammatory and antioxidant effects, leading to several investigations of whether statins have a neuroprotective effect and may benefit patients with Parkinson's disease (PD). However, the potential mechanisms of this class of medications as modifiers of the course of PD in already diagnosed patients is still unclear.

Objectives: To assess the effectiveness of statins as modifiers of established PD.

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Multiuser design of an architecture for social robots in education: teachers, students, and researchers perspectives.

Front Robot AI

December 2024

Robot Learning Laboratory, Instituto de Ciências Matemáticas e de Computação (ICMC), University of São Paulo (USP), SãoCarlos, Brazil.

Research on social assistive robots in education faces many challenges that extend beyond technical issues. On one hand, hardware and software limitations, such as algorithm accuracy in real-world applications, render this approach difficult for daily use. On the other hand, there are human factors that need addressing as well, such as student motivations and expectations toward the robot, teachers' time management and lack of knowledge to deal with such technologies, and effective communication between experimenters and stakeholders.

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Background & Aims: Muscle strength is a key predictor of both quality of life and mortality. Although numerous studies have investigated the relationship between omega-3 (ω-3) intake and muscle strength, the evidence remains inconclusive. Furthermore, it is unclear whether this association is influenced by protein intake.

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Effect of Graphene-Based Coating 3D Printing Process on the Remanence and Corrosion of Sintered NdFeB Magnets.

3D Print Addit Manuf

December 2024

Materials Science and Technology Center (CCTM), Nuclear, and Energy Research Institute (IPEN), University of São Paulo (USP), São Paulo, São Paulo, Brazil.

This study describes a 3D fused deposition modeling (FDM) printing process using a graphene-impregnated polylactic acid (G-PLA) filament to create a new type of rigid, plastic, nonconductive, and anticorrosion layer. Therefore, the possibility of 3D printing a plastic layer using FDM methods is demonstrated herein. A commercial magnet such as N35 NdFeB can be used to produce an efficient shielding film by additive manufacturing.

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Canine oral melanoma (COM) is a promising target for immunomodulatory therapies aimed at enhancing the immune system's antitumor response. Given that adipose-derived mesenchymal stem cells (Ad-MSCs) possess immunomodulatory properties through cytokine release, we hypothesized that co-culturing Ad-MSCs and canine peripheral blood mononuclear cells (PBMCs) could stimulate interleukin (IL) production against melanoma cell lines (MCCLs) and help identify therapeutic targets. This study evaluated IL-2, IL-8, and IL-12 expressions in co-culture with MCCL, Ad-MSCs, and PBMCs and assessed the relationship between gene expression, cell viability, and migration.

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Coconut Oil Mitigates the Effects of Aging on the Mongolian Gerbil Prostate.

Prostate

December 2024

Department of Biological Sciences, Institute of Biosciences, Humanities and Exact Sciences, São Paulo State University (UNESP), São José do Rio Preto, São Paulo, Brazil.

Background: Benign prostatic hyperplasia (BPH) is a disease linked to the hormonal imbalance that occurs during aging and over the last decades, complementary and alternative medicines have come on the scene as a treatment option for BPH, such as herbal medicines. Coconut oil has been shown to be capable of interfering in testosterone-induced BPH. However, until now there is no study of the effect of coconut oil during aging.

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Objectives: This study aimed to evaluate, using micro-computed tomography (microCT), the impact of various mechanized systems on the geometry of the root canal system (RCS) and dentin thickness in mandibular first molars. The hypothesis proposed that different systems would produce significant variations in RCS preparation.

Methods: Mesial and distal canals of mandibular molars were selected and divided into five groups (n=10) based on the system used: 2Shape (25.

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Improving serum redox balance, inflammatory status, physical function, and cognitive ability through dual-task resistance training and detraining in nursing home residents.

Exp Gerontol

December 2024

Postgraduate Program in Physical Education, Federal University of Mato Grosso, Cuiabá, MT, Brazil; Center for Proteomic and Biochemical Analysis, Postgraduate Program in Genomic Sciences and Biotechnology, Catholic University of Brasília, Brasília, Brazil. Electronic address:

Objective: This study investigated the effects of dual-task resistance training (RT) and detraining on physical function, cognitive capacity, lipid profile, renal function, oxidative stress markers, and chronic inflammation of institutionalized older adults.

Methods: The study involved 11 older adults (83.09 ± 8.

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This study evaluated the bond strength (BS) of conventional, anatomized, adjustable, and CAD/CAM fiberglass post systems. Forty maxillary canine roots were weakened, endodontically treated, and divided into four groups (n=10). A slice from each of the three sections (cervical, middle, apical) of the root canal was subjected to the push-out test and the failure pattern was subsequently analyzed.

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We established a proof-of-concept model system for the biological healing of periapical lesions using stem cell spheroids. Mesenchymal stem cells from human exfoliated deciduous teeth (SHED) were cultured in a 2D monolayer and then as 3D multicellular spheroids. An image of a periapical lesion of an upper lateral incisor tooth was obtained by computed tomography and was used as a model for photopolymer resin 3D printing to generate a negative frame of the lesion.

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Objective: Cardiovascular disease (CVD) remains a significant public health challenge in China. Accurate perception of individual CVD risk is crucial for timely intervention and preventive strategies. This study aimed to determine the alignment between CVD risk perception levels and objectively calculated CVD risk levels, then investigate the disparity in physical activity and healthy diet habits among distinct CVD risk perception categories.

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Background: Myeloid neoplasms encompass disorders characterized by abnormal myeloid cell proliferation and differentiation, including myelodysplastic syndromes (MDS), myeloproliferative neoplasms, acute myeloid leukemia (AML), and chronic myeloid leukemia (CML). Formin-like protein 1 (FMNL1) is involved in the regulation of the actin cytoskeleton and is predominantly expressed in hematopoietic cells. Given its role in leukemia cell proliferation, survival, migration, and invasion, this study investigates FMNL1 expression in normal hematopoiesis and myeloid neoplasms and explores associations with clinical-laboratory characteristics, mutational status, and survival outcomes in AML.

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Background: The use of FMS-like tyrosine kinase 3 () as a crucial target for kinase inhibitors is well established, but its association with immune infiltration remains unclear. This study aimed to explore the relationship between mutations and immune checkpoint molecules (ICMs) in patients with acute myeloid leukemia (AML).

Methods: The Cancer Genome Atlas (TCGA) and Genotype-Tissue Expression (GTEx) databases were used to identify the ICMs associated with mutations.

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Background: Chagas disease (CD) is neglected that affects vulnerable individuals, whose majority has low ability to understand health information.

Objectives: To assess health literacy and its association with sociodemographic, clinical, and quality of life (QoL) characteristics.

Design And Setting: A cross-sectional study the participants with Chagas disease (ChD) were identified through serological diagnosis during blood donation, while those without the disease were seronegative blood donors.

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Women with gestational diabetes mellitus show a high risk of developing Gestational Diabetes Induced Myopathy (GDiM). GDiM is characterized by significant pelvic floor skeletal muscle atrophy and urinary incontinence. This study aimed to develop a natural rubber latex (NRL) based biodevice with mesenchymal/stromal stem cells (MSCs) for skeletal muscle regeneration for women with GDiM.

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Dietary Energy Sources Affect Cecal and Fecal Microbiota of Healthy Horses.

Animals (Basel)

December 2024

Department of Animal Science, School of Animal Science and Food Engineering (FZEA), University of São Paulo (USP), Pirassununga 13635-900, São Paulo, Brazil.

Different energy sources are often used in horse diets to enhance health and performance. Understanding how diet impacts the cecal and fecal microbiota is crucial for meeting the nutritional needs of horses. High-throughput sequencing and qPCR were used to compare the fecal and cecal microbiota of five healthy horses receiving three different diets: hay diet (HAY), hay + starch and sugar (SS), and hay + fiber and oil ingredients (FO).

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Proper monitoring of rotating machines is responsible for the efficiency in detecting, diagnosing, or even prognosing failures. Effective monitoring can lead to increased economic viability of any equipment, as it may reduce costly repairs, decrease downtime, and increase safety. Knowing the behaviour of a machine promotes better monitoring of its operation and maintenance.

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Acute Ecotoxicity and Bioconcentration Tests for Se(IV) in Nile tilapia ().

ACS Omega

December 2024

National Institute for Alternative Technologies for Detection, Toxicological Assessment and Removal of Emerging Micropollutants and Radioactives (INCT-DATREM), Department of Chemistry and Environmental Science, São Paulo State University (UNESP), São José do Rio Preto, SP, 15054-000, Brazil.

Selenium is one of the most important trace element micronutrients for the global biota, mainly due to its role in protecting against oxidative stress. However, this element can become toxic when present at concentrations slightly higher than those needed for metabolic purposes. It can be transferred through the food chain toward higher trophic levels, with bioaccumulation and biomagnification leading to possible toxicity.

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Letter to the Editor on Assessment of Muscular Weakness in Severe Sleep Apnea Patient.

Otolaryngol Head Neck Surg

December 2024

Craniofacial Research Support Center, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto (SP), São Paulo, Brazil.

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EHMT2 as a Candidate Gene for an Autosomal Recessive Neurodevelopmental Syndrome.

Mol Neurobiol

December 2024

Department of Genetics and Evolutionary Biology, Institute of Biosciences, Human Genome and Stem Cell Research Center, University of Sao Paulo (USP), Sao Paulo, SP, Brazil.

Neurodevelopmental disorders (NDD) comprise clinical conditions with high genetic heterogeneity and a notable enrichment of genes involved in regulating chromatin structure and function. The EHMT1/2 epigenetic complex plays a crucial role in repression of gene transcription in a highly tissue- and temporal-specific manner. Mutations resulting in heterozygous loss-of-function (LoF) of EHMT1 are implicated in Kleefstra syndrome 1 (KS1).

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The presence of complex dyes, which possess four or more aromatic rings, is pervasive in environmental matrices. Nanomaterials offer a promising avenue for their removal. In this study, we synthesized novel magnetic nanocomposites comprising nanochitosan (nCS) and iron nanoparticles through the application of green and conventional protocols.

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Influence of Surface Roughness on the Adhesion of Hydroxyapatite Coatings to Titanium and Titanium Alloy Surfaces: A Systematic Review of in vitro Experimental Studies.

Eur J Prosthodont Restor Dent

December 2024

Master's student, Department of Dental Materials and Prosthodontics, Ribeirão Preto, Dental School, University of São Paulo (USP), Ribeirão Preto, Brazil.

This systematic review gathered evidence to identify the influence of roughness on titanium surfaces on the adhesion of hydroxyapatite coatings. This research followed the PRISMA guidelines and was registered on the Open Science Framework (osf.io/cxrsf).

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Objectives: To gather the perspectives of APS ACTION members regarding the strengths and limitations of Damage Index for Antiphospholipid Syndrome (DIAPS); and establish recommendations for the improvement of DIAPS.

Methods: APS ACTION members were invited to answer a survey regarding their satisfaction with DIAPS scoring system and individual items. The level of agreement (LoA) among members with the inclusion of individual items in DIAPS was calculated (LoA of <75% was considered disagreement).

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