2,421 results match your criteria: "University of Sao Paulo-School of Medicine[Affiliation]"
Introduction: Associations between amyloid-tau-neurodegeneration (ATN) plasma biomarkers and cognition have not been characterized in adults with type 1 diabetes (T1D).
Methods: Using data from participants in the Glycemic Variability and Fluctuations in Cognitive Status in Adults with T1D (GluCog) study ( = 114), we evaluated associations between phosphorylated tau (pTau)181, pTau217, β-amyloid 42/40 ratio, glial fibrillary acidic protein (GFAP), and neurofilament light (NfL) and self-administered digital cognitive tests, adjusting for age, sex, education, comorbidities (e.g.
J Allergy Clin Immunol
December 2024
Division of Allergy and Immunology, Departments of Medicine and Pediatrics, Massachusetts General Hospital, Harvard Medical School, Boston, Mass. Electronic address:
Sleep
October 2024
Incor, University of São Paulo School of Medicine, São Paulo, SP, Brazil.
Study Objectives: Sleep characteristics are associated with cardiovascular disease (CVD) risk and both sleep and CVD risk vary by gender. Our objective was to examine associations between polysomnographic sleep characteristics and CVD risk after excluding moderate-severe sleep apnea, and whether gender modifies these associations.
Methods: This was a cross-sectional study with at-home polysomnography in adults in Brazil (n= 1,102 participants with apnea-hypopnea index (AHI)<15 events/hour).
Ecancermedicalscience
August 2024
Department of Oncology, ICESP - Instituto do Cancer do Estado de Sao Paulo, University of Sao Paulo School of Medicine, Sao Paulo, SP 01246-000, Brazil.
Hepatocellular carcinoma (HCC) is a lethal malignancy associated with cirrhosis and liver dysfunction. The aim of this study is to characterize a cohort of patients with advanced HCC according to liver function-related variables and evaluate the prognostic significance of Child-Pugh (CP) and albumin-bilirubin (ALBI) scores. A database of 406 HCC patients treated between 2009 and 2023 was retrospectively evaluated.
View Article and Find Full Text PDFSci Rep
October 2024
Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
Vaccination has played a critical role in mitigating COVID-19. Despite the availability of licensed vaccines, there remains a pressing need for improved vaccine platforms that provide high protection, safety, and versatility, while also reducing vaccine costs. In response to these challenges, our aim is to create a self-adjuvanted vaccine against SARS-CoV-2, utilizing Virus-Like Particles (VLPs) as the foundation.
View Article and Find Full Text PDFRadiol Case Rep
December 2024
Center of Acupuncture, Department of Orthopaedics and Traumatology, University of Sao Paulo School of Medicine, Sao Paulo, Brazil.
Int Neurourol J
September 2024
Division of Urology, University of Sao Paulo School of Medicine, Sao Paulo, Brazil.
J Urol
January 2025
Department of Urology, Hospital das Clínicas, University of São Paulo Medical School, São Paulo, Brazil.
Cent European J Urol
February 2024
Surgical Technique and Experimental Surgery, University of São Paulo School of Medicine, São Paulo, Brazil.
Introduction: Robot-assisted laparoscopic surgery (RALS) and conventional laparoscopic surgery (LS) are the main options for ileal ureteral replacement (IUR). It is not clear which option is superior. The purpose of this study is to compare RALS and LS for IUR.
View Article and Find Full Text PDFPlast Reconstr Surg
September 2024
Assistant Professor - Plastic Surgery Division - Hospital Sírio-Libanês - São Paulo/Brazil. Chief - Breast Surgery Group, Plastic Surgery Division University of São Paulo School of Medicine. Coordinator of Plastic Surgery Department - Hospital Moriah. Member of Brazilian Society of Plastic Surgery (SBCP). International Member of American Society of Plastic Surgeons (ASPS).
Minerva Urol Nephrol
October 2024
Surgical Technique and Experimental Surgery Department, University of São Paulo School of Medicine, São Paulo, Brazil -
Int J Mol Sci
August 2024
Department of Internal Medicine, Medical School, São Paulo State University (UNESP), Botucatu 18618-687, SP, Brazil.
Ann Hepatol
September 2024
LIM-07, Institute of Tropical Medicine, Department of Gastroenterology, University of São Paulo School of Medicine, São Paulo, Brazil.
Diabetol Metab Syndr
September 2024
Faculty of Health and Medical Sciences, School of Psychology, University of Surrey, Guildford, Surrey, GU2 7XH, UK.
Background: Diabetes and poor glycaemic control have been shown to negatively impact cognitive abilities, while also raising risk of both mood disorders and brain structural atrophy. Sites of atrophy include the hippocampus, which has been implicated in both memory performance and depression. The current study set out to better characterise the associations between poor glycaemic control, memory performance, and depression symptoms, and investigate whether loss of hippocampal volume could represent a neuropathological mechanism underlying these.
View Article and Find Full Text PDFSurg Neurol Int
August 2024
Department of Neurosurgery, University of Sao Paulo, Facultade das Clinicas, Sao Paulo, Brazil.
Background: The pterional craniotomy, described by Yasargil and Fox in 1975, constitutes the most traditional and important surgical access in vascular neurosurgery. Minimally invasive alternatives include the minipterional (MP) and lateral supraorbital (LSO) craniotomies, which avoid complications such as injury to the frontal branch of the facial nerve, temporal muscle dysfunction, depression of the craniotomy site, frontal sinus opening, and cosmetically unacceptable outcomes. We evaluated and compared the exposures provided by MP and LSO craniotomies through quantitative measurements of the surgical exposure area around the circle of Willis and parasellar regions, as well as angular and linear exposures of the internal carotid artery (ICA) bifurcation, middle cerebral artery (MCA), midpoint of the anterior communicating artery, and tip of the basilar artery (BA).
View Article and Find Full Text PDFWorld J Pediatr Congenit Heart Surg
September 2024
Laboratory of Pathology, Heart Institute (InCor), University of Sao Paulo School of Medicine, São Paulo, Brazil.
In this review, we approach the main morphologic and developmental aspects of the congenital cardiovascular malformation known as tetralogy of Fallot with pulmonary atresia. It is recognized that pulmonary atresia associated with a deficient ventricular septation can occur in several situations. However, the tetralogy presentation in particular, with frequent but not invariable concomitance of systemic-to-pulmonary collateral arteries supplying the lungs entirely or in part, poses surgical challenges.
View Article and Find Full Text PDFAnn Surg
September 2024
Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital and National Cancer Centre Singapore, Singapore.
Dig Endosc
December 2024
Gastrointestinal Endoscopy Unit, Clinical Hospital, University of São Paulo School of Medicine, São Paulo, Brazil.
Objectives: Endoscopic resection is the preferred approach to treat early Barrett's neoplasia, reducing the need for surgical interventions. However, the best choice between endoscopic mucosal resection (EMR) or endoscopic submucosal dissection (ESD) remains unclear. The study aimed to compare the efficacy and safety of EMR vs.
View Article and Find Full Text PDFAntibiotics (Basel)
August 2024
Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.
: Typhoid fever caused by serovar Typhi continues to pose a significant risk to public health in developing countries, including Pakistan. This study investigated the epidemiological factors linked to suspected and confirmed infections in Peshawar's hospital population. : A total of 5735 blood samples of patients with suspected enteric fever were collected from September 2022 to November 2023.
View Article and Find Full Text PDFWorld Allergy Organ J
August 2024
Clinical Immunology and Allergy Division, University of São Paulo School of Medicine, Brazil.
Hypertens Res
October 2024
Department of Physiology, Federal University of São Paulo-School of Medicine, São Paulo, Brazil.
Oral Dis
November 2024
Post Graduate Program in Dentistry at Universidade Santo Amaro, São Paulo, Brazil.
Neurocrit Care
August 2024
Division of Neurosurgery, University of São Paulo, Street Dr. Ovídio Pires de Campos, 225 - Cerqueira César, São Paulo, SP, 05403-010, Brazil.
Decompressive craniectomy is used to alleviate intracranial pressure in cases of traumatic brain injury and stroke by removing part of the skull to allow brain expansion. Traditionally, this procedure is followed by a watertight dural suture, although evidence supporting this method is not strong. This meta-analysis examines the feasibility of the open-dura (OD) approach versus the traditional closed-dura (CD) technique with watertight suturing.
View Article and Find Full Text PDFFront Immunol
July 2024
Nephrology and Dialysis Center, Oswaldo Cruz German Hospital, São Paulo, Brazil.
Inflamm Bowel Dis
July 2024
Gastrointestinal Endoscopy Unit, Hospital das Clínicas, University of São Paulo School of Medicine, São Paulo, Brazil.
Background: Crohn's disease (CD) is a chronic inflammatory condition of the gastrointestinal tract. Current drugs are not effective for treating the primary fibrotic component of CD. Recommended invasive treatments include endoscopic balloon dilation, surgery with resection, or strictureplasty.
View Article and Find Full Text PDF