3 results match your criteria: "University of Sao Paulo; Sao Paulo[Affiliation]"
Multicenter Candida auris outbreak caused by azole-susceptible clade IV in Pernambuco, Brazil.
Mycoses
June 2024
Disciplina de Infectologia, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil.
Background: Candida auris is an emerging multidrug-resistant yeast, frequently causing outbreaks in health care facilities. The pathogen persistently colonises human skin and inanimate surfaces such as catheters, aiding to its spread. Moreover, colonisation is a risk factor to develop invasive infection.
View Article and Find Full Text PDFHuman Papillomavirus Intermittence and Risk Factors Associated With First Detections and Redetections in the Ludwig-McGill Cohort Study of Adult Women.
J Infect Dis
August 2023
Division of Cancer Epidemiology, Gerald Bronfman Department of Oncology, McGill University, Montréal, Canada.
Article Synopsis
- The study looked at how often women in São Paulo, Brazil experience the reappearance of the same HPV genotype after initially testing negative, tracking women aged 18-60 over a median of 6.5 years.
- Out of almost 2,200 women, the cumulative incidence of HPV redetection was 6.6% after one year and 14.8% after five years, with no significant links found between redetection and factors like age or having a new sexual partner.
- The prevalence of high-grade squamous intraepithelial lesions was similar between first detections and redetections, suggesting that many redetections are likely due to the reactivation of previously latent infections.
DeepAMR for predicting co-occurrent resistance of Mycobacterium tuberculosis.
Bioinformatics
September 2019
Institute of Biomedical Engineering, Department of Engineering Science, University of Oxford, Oxford, UK.
Motivation: Resistance co-occurrence within first-line anti-tuberculosis (TB) drugs is a common phenomenon. Existing methods based on genetic data analysis of Mycobacterium tuberculosis (MTB) have been able to predict resistance of MTB to individual drugs, but have not considered the resistance co-occurrence and cannot capture latent structure of genomic data that corresponds to lineages.
Results: We used a large cohort of TB patients from 16 countries across six continents where whole-genome sequences for each isolate and associated phenotype to anti-TB drugs were obtained using drug susceptibility testing recommended by the World Health Organization.