5 results match your criteria: "University of San Carlos de Guatemala[Affiliation]"
HLA-DRB1 and HLA-DQB1 genes in patients diagnosed with systemic lupus erythematosus in Guatemala.
Hum Immunol
May 2024
Histocompatibility Laboratory, Nephrology and Transplant Department, General San Juan de Dios Hospital, Guatemala City, Guatemala.
Systemic lupus erythematosus (SLE) is an autoimmune disorder that impacts connective tissue and can affect various organs and systems within the body. One important aspect of this disease is the role of the human leukocyte antigen (HLA) system, a protein complex that plays a role in the immune response. Specifically, the HLA-DRB1 and HLA-DQB1 genes have been implicated in the development of SLE.
View Article and Find Full Text PDFBarriers and Opportunities for Clinical Nutritionists in 13 Latin American Countries: A Qualitative Study.
J Prim Care Community Health
December 2023
Costa Rican Association of Dietitians and Nutritionists (ACDYN), San José, Costa Rica.
A clinical nutritionist (CN) is a university-educated professional trained to perform preventive and recovery functions in the health of patients. The actions of these professionals, both worldwide and in Latin America, may face barriers and opportunities that require careful identification and examination. The main objective of this study is to identify the most important barriers and opportunities for the clinical nutritionist in 13 Latin American countries.
View Article and Find Full Text PDFAn updated examination of the perception of barriers for pharmacogenomics implementation and the usefulness of drug/gene pairs in Latin America and the Caribbean.
Front Pharmacol
May 2023
Laboratory of Chemical Carcinogenesis and Pharmacogenetics, Department of Basic-Clinical Oncology (DOBC), Faculty of Medicine, University of Chile, Santiago, Chile.
Article Synopsis
- Pharmacogenomics (PGx) is a growing field in developing countries, particularly in Latin America and the Caribbean (LAC), but research and information are limited, making it challenging to apply findings across diverse populations.
- The study reviewed PGx knowledge among the LAC scientific community, identified barriers to its clinical use, and surveyed 106 professionals to evaluate these obstacles, revealing that the primary barrier is the lack of guidelines for implementing PGx in practice.
- Despite these challenges, LAC has contributed 3.44% of global PGx publications and identified gene/drug pairs, such as tamoxifen and clopidogrel, as significant for improving genomic medicine responses, although cost-effectiveness concerns remain a critical issue.
Self-inflicted transorbital pontine stab injury with a retained pen.
Proc (Bayl Univ Med Cent)
December 2020
Department of Neurosurgery, University of San Carlos de Guatemala, Guatemala City, Guatemala.
Self-inflicted transorbital stab injuries are not commonly seen in clinical practice. These lesions usually lead to major disability depending on the intracranial structures transected. We present a case of a 34-year-old man with a self-inflicted stab injury in his right orbit from a pen.
View Article and Find Full Text PDFDevelopment of a surgical competency assessment tool for sentinel lymph node dissection by minimally invasive surgery for endometrial cancer.
Int J Gynecol Cancer
May 2021
Center for Clinical Research, Faculty of Medicine, University of Queensland, Herston, Queensland, Australia
Introduction: Sentinel lymph node dissection is widely used in the staging of endometrial cancer. Variation in surgical techniques potentially impacts diagnostic accuracy and oncologic outcomes, and poses barriers to the comparison of outcomes across institutions or clinical trial sites. Standardization of surgical technique and surgical quality assessment tools are critical to the conduct of clinical trials.
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