Major cardiovascular events and subsequent risk of kidney failure with replacement therapy: a CKD Prognosis Consortium study.

Aims: Chronic kidney disease (CKD) increases risk of cardiovascular disease (CVD). Less is known about how CVD associates with future risk of kidney failure with replacement therapy (KFRT).

Methods And Results: The study included 25 903 761 individuals from the CKD Prognosis Consortium with known baseline estimated glomerular filtration rate (eGFR) and evaluated the impact of prevalent and incident coronary heart disease (CHD), stroke, heart failure (HF), and atrial fibrillation (AF) events as time-varying exposures on KFRT outcomes.

Comfort driven design of innovative products: A personalized mattress case study.

Background: Human-centred design asks for wellbeing and comfort of the customer/worker when interacting with a product. Having a good perception-model and an objective method to evaluate the experienced (dis)comfort by the product user is needed for performing a preventive comfort evaluation as early as possible in the product development plan. The mattress of a bed is a typical product whose relevance in everyday life of people is under-evaluated.

A body-shaped lumbar-sacral support for improving car-seat comfort.

Background: Nowadays, the ergonomic study of the driving position is a critical aspect of automotive design. Indeed, due to the rising needs on the market, one focus for car industries is to improve the perceived comfort related to the cars' interior. Driving a car for a prolonged time could cause complaints in some body-regions, especially in the lumbar-sacral area.