Frequency-dependent effects of superimposed NMES on spinal excitability in upper and lower limb muscles.

Superimposing neuromuscular electrical stimulation (NMES) on voluntary contractions has proven to be highly effective for improving muscle strength and performance. These improvements might involve specific adaptations occurring at cortical and spinal level. The effects of NMES on corticospinal activation seem to be frequency dependent and differ between upper and lower limb muscles.

Electrophysiological indexes of the cognitive-motor trade-off associated with motor response complexity in a cognitive task.

Complex actions require more cognitive and motor control than simple ones. Literature shows that to face complexity, the brain must make a compromise between available resources usually giving priority to motor control. However, literature has minimally explored the effect of the motor response complexity on brain processing associated with cognitive tasks.

Inflammation: The Beauty or the Beast? Vitamins, Nutritional Supplements, Antioxidant Therapy, and Modulators of Inflammation as Therapeutic Interventions.

The importance of inflammation in disease development is now well known not only for acute states but also for chronic pathologies [...

Beliefs on the ability to regulate negative emotions mediates the effects of competitive anger on task-focused self-efficacy in taekwondo athletes.

Self-efficacy (SE) refers to an individual's belief in their own ability to successfully execute specific tasks and produce desired outcomes. The focused SE on specific sports tasks has been shown to impact athletic performance by interacting with other self-evaluation processes, like self-efficacy beliefs in emotion-related regulation and effective emotion regulation. This study aims at investigating the mediating effect of SE in regulating negative affect in the relationship between anger and taekwondo task-focused SE.

The role of TandemHeart combined with ProtekDuo as right ventricular support device: A simulation approach.

Background And Objective: Right ventricular failure increases short-term mortality in the setting of acute myocardial infarction, cardiogenic shock, advanced left-sided heart failure and pulmonary arterial hypertension. Percutaneous and surgically implanted right ventricular assist devices (RVAD) have been investigated in different clinical settings. The use of the ProtekDuo™ is currently a promising approach due to its features such as groin-free approach leading to early mobilisation, easy percutaneous deployment, compatibility with different pumps and oxygenators, and adaptability to different configurations.

Sexual Dimorphism in Sex Hormone Metabolism in Human Skeletal Muscle Cells in Response to Different Testosterone Exposure.

Muscle tissue is an important target of sex steroids, and particularly, testosterone plays essential roles in muscle cell metabolism. Wide ranges of studies have reported sex differences in basal muscle steroidogenesis, and recently several genes have been identified to be regulated by androgen response elements that show innate sex differences in muscle. However, studies accounting for and demonstrating cell sexual dimorphism in vitro are still scarce and not well characterized.

The Emerging Role of Phosphodiesterase 5 Inhibition in Neurological Disorders: The State of the Art.

Growing evidence suggests that neuroinflammation is not just a consequence of neurodegeneration in pathologies such as Alzheimer's disease, Parkinson's disease, Huntington's disease or Amyotrophic lateral sclerosis, but it is rather a determinant factor, which plays a pivotal role in the onset and progression of these disorders. Neuroinflammation can affect cells and processes in the central nervous system (CNS) as well as immune cells, and might precede protein aggregation, which is a hallmark of the neurodegenerative process. Standard treatment methods are far from being able to counteract inflammation and delay neurodegeneration.

Focal Versus Combined Focal Plus Radial Extracorporeal Shockwave Therapy in Lateral Elbow Tendinopathy: A Retrospective Study.

Lateral epicondylitis of the elbow, commonly known as tennis elbow, is a musculoskeletal disorder characterized by pain and degeneration of the common extensor tendon. Despite various treatments, optimal management remains debated. This study aimed to compare the effectiveness of focal extracorporeal shockwave therapy (F-ESWT) alone versus a combination of focal and radial pressure waves (F-ESWT+R-PW) in treating chronic lateral epicondylitis.

Bridging Generations Through Movement: "How and Why" Intergenerational Programs Operate-A Systematic and Narrative Review.

Well-being and social interaction are among the primary goals to be achieved for the elderly. Intergenerational physical activity (PA) has gained increasing attention due to its potential to encourage PA and social interaction, providing both social and physical benefits to both younger and older individuals. This review aimed to gain a deeper understanding of the potential roles of PA in facilitating intergenerational interactions and provide practical insights.

Breath Analysis via Gas Chromatography-Mass Spectrometry (GC-MS) in Chronic Coronary Syndrome (CCS): A Proof-of-Concept Study.

This proof-of-concept study aimed to assess the diagnostic potential of gas chromatography-mass spectrometry (GC-MS) in profiling volatile organic compounds (VOCs) from exhaled breath as a diagnostic tool for the chronic coronary syndrome (CCS). Exhaled air was collected from patients undergoing invasive coronary angiography (ICA), with all samples obtained prior to ICA. Post hoc, patients were divided into groups based on coronary lesion severity and indications for revascularization.

Effects of sulphur thermal water inhalations in long-COVID syndrome: Spa-centred, double-blinded, randomised case-control pilot study.

Background: The long-COVID syndrome is characterised by a plethora of symptoms. Given its social and economic impact, many studies have stressed the urgency of proposing innovative strategies other than hospital settings. In this double-blinded, randomised, case-control trial, we investigate the effects of sulphur thermal water inhalations, rich in HS, compared to distilled water inhalations on symptoms, inflammatory markers and nasal microbiome in long-COVID patients.

Game schedule, travel demands and contextual factors influence key game-related statistics among the top European male basketball teams.

This study examined the effects of game schedule, travel demands and contextual factors on team game-related statistics during a full season. The top 10 teams competing in the 2020-2021 Euroleague basketball season were included where game-related statistics from their respective national competitions and the Euroleague competition were retrieved (761 games). Hierarchical linear regression models were computed to evaluate the effects of distance travelled, game schedule and contextual factors for the previous and current games (league, season phase, opponent level, game outcome, score differential) on key performance indicators (points, shooting, rebounds, assists, turnovers, fouls).

Rethinking of phosphodiesterase 5 inhibition: the old, the new and the perspective in human health.

The phosphodiesterases type 5 (PDE5) are catalytic enzymes converting the second messenger cyclic guanosine monophosphate (cGMP) to 5' GMP. While intracellular cGMP reduction is associated with several detrimental effects, cGMP stabilization associates with numerous benefits. The PDE5 specific inhibitors, PDE5i, found their explosive fortune as first-line treatment for erectile dysfunction (ED), due to their powerful vasoactive properties.

Occurrence of Uncultured spp. in Treated Wastewater Effluent and Its Impact on Human Health (SCA.Re.S Project).

Wastewater treatment plants (WWTPs) provide optimal conditions for the environmental spread of . As part of the Evaluation of Sanitary Risk Related to the Discharge of Wastewater to the Ground (SCA.Re.

In Silico Predicting the Presence of the S100B Motif in Edible Plants and Detecting Its Immunoreactive Materials: Perspectives for Functional Foods, Dietary Supplements and Phytotherapies.

The protein S100B is a part of the S100 protein family, which consists of at least 25 calcium-binding proteins. S100B is highly conserved across different species, supporting important biological functions. The protein was shown to play a role in gut microbiota eubiosis and is secreted in human breast milk, suggesting a physiological trophic function in newborn development.