525 results match your criteria: "University of Rome "Guglielmo Marconi"[Affiliation]"

The Body as a Vessel for Trauma: The Clinical Case Study of Aisha.

Brain Sci

January 2025

Associazione di Psicologia Cognitiva APC e Scuola di Psicoterapia Cognitiva SPC, 00185 Rome, Italy.

This case study examined the process of integration of cognitive behavioral therapy (CBT) and sensorimotor psychotherapy (SP) in three-phase trauma treatment with a 32-year-old female Bengali refugee with Complex Post Traumatic Disorder (C-PTSD). The treatment was provided in a Western country. The client's improvement was assessed by using self-report assessments of post-traumatic, dissociative, and depressive symptoms.

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Background/objectives: Based on previous data reporting the status of health professionals' training about sleep clinical psychophysiology, insomnia, and its treatment in the US and Canada, this paper aims at providing a snapshot of the Italian situation, considering health professionals qualified to offer cognitive behavioral therapy (CBT). Adding information on different countries is important, as national health systems differ significantly, and distinct evidence-based pathways for change may be proposed.

Methods: Two hundred and thirteen CBT professionals (180 females; 33 males) answered a 5 min survey about their training and experience in recognizing and treating behavioral sleep disorders in their practice.

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Objective: Self-criticism (SC) is a central transdiagnostic factor in several psychopathological conditions, influencing the development and maintenance of symptomatology. The importance of this construct has stimulated quantitative and qualitative research about it. The main purpose of this systematic review is to highlight which qualitative methods have been used most frequently and which are most suitable for studying SC.

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Sound detection in fishes relies on the inner ear and peripheral structures, such as calcareous otoliths, which play a crucial role in perceiving movement, orientation, and balance. Otoliths, in particular, respond to various environmental factors including temperature, salinity, and food availability, making them valuable indicators of ecological conditions. This study applies geometric morphometrics (GMM) to analyze the otolith shape of Diplodus annularis (Linnaeus, 1758) from two distinct populations located in the Gulf of Asinara (Porto Torres, Sardinia) and the northern Adriatic Sea (Le Tegnue).

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The brain/cognitive/neural reserve concept suggests that lifelong experiences, from early life through adulthood, make the brain more resilient to neuronal damage. Modifiable lifestyle factors, such as sleep, can support the development and enhance such a reserve, helping to counteract age- or disease-related brain changes and their impact on cognition. Sleep plays a crucial role in cognitive functioning, and disruptions or disorders may increase neurodegenerative risks.

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Proper polarization of newly generated neurons is a critical process for neural network formation and brain development. The pan-neurotrophin p75 receptor plays a key role in this process localizing asymmetrically in one of the differentiating neurites and specifying its axonal identity in response to neurotrophins. During axonal specification, p75 levels are transiently modulated, yet the molecular mechanisms underlying this process are not known.

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The advent of bioprinting has enabled the creation of precise three-dimensional (3D) cell cultures suitable for biomimetic in vitro models. In this study, we developed a novel protocol for 3D printing methacrylated collagen (ColMa, or PhotoCol®) combined with tendon stem/progenitor cells (hTSPCs) derived from human tendon explants. Although pure ColMa has not previously been proposed as a printable hydrogel, this paper outlines a robust and highly reproducible pipeline for bioprinting this material.

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Temporal parameters are crucial for understanding running performance, especially in elite sports environments. Traditional measurement methods are often labor-intensive and not suitable for field conditions. This study seeks to provide greater clarity in parameter estimation using a single device by comparing it to the gold standard.

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Background: Patients with Complex Trauma (CT) may have an impaired ability to trust others and build intimate relationships due to non-integrated representations of self and others. This sometimes leads to an oscillation between needing and fearing intimacy in their adult relationships. This dynamic can occur in the therapeutic relationship, undermining the effectiveness of therapy and affecting the mental health of both the patient and the therapist.

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: Large-scale vaccination was crucial to address the global COVID-19 pandemic and its associated health risks, including fatal and disabling diseases. However, there were significant challenges to be overcome to ensure the safe and effective implementation of the vaccination program. The aim of the present study was to assess patient safety threats related to the anti-COVID-19 large-scale vaccination process.

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Cognitive-behavioural therapy for insomnia mechanism of action: Exploring the homeostatic K-complex involvement.

J Sleep Res

December 2024

Vita-Salute San Raffaele University, Department of Clinical Neurosciences, Neurology-Sleep Disorders Center, IRCCS San Raffaele Scientific Institute, Milan, Italy.

Article Synopsis
  • This study investigates how K-complexes (KC), a specific type of brainwave, relate to the effectiveness of Cognitive-Behavioral Therapy for Insomnia (CBT-I), which is the main treatment for chronic insomnia.
  • Researchers conducted a multicenter study with 98 insomnia patients undergoing a 6-8 week CBT-I program, evaluating their sleep using polysomnography and an insomnia severity index before and after treatment.
  • The results indicate that KC density, particularly its change after treatment, can predict how well patients respond to CBT-I and significantly correlates with improved sleep pressure, suggesting KC is an important biomarker for insomnia treatment.
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Wearable technology has advanced significantly, offering real-time monitoring of athletes' physiological parameters and optimizing training and recovery strategies. Recent developments focus on biosensor devices capable of monitoring biochemical parameters in addition to physiological ones. These devices employ noninvasive methods such as sweat analysis, which reveals critical biomarkers like glucose, lactate, electrolytes, pH, and cortisol.

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Controversial role of lactoferrin in cancer: A narrative review.

Biomed Pharmacother

December 2024

Department of Science, Roma Tre University, Viale Guglielmo Marconi 446, Rome 00146,  Italy; National Institute of Biostructures and Biosystems (INBB), Via dei Carpegna 19, Rome 00165, Italy.

Lactoferrin (Lf) is a positively charged iron-binding glycoprotein that has piqued the scientific community's interest due to its pleiotropic behavior, exhibiting a wide range of biological activities, including antimicrobial, antioxidant, anti-inflammatory, immunomodulatory, and anticancer effects. This narrative review explores the current understanding of Lf's role in cancer, focusing on the endogenously expressed human full-length and ΔLf isoforms, and the effects of treatment with exogenous human and bovine Lf. We evaluated and compared the mechanisms by which Lf influences tumorigenesis and cancer progression, focusing on its impact on key processes such as cell growth, apoptosis, angiogenesis, cell migration, and invasiveness.

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Article Synopsis
  • The CMS experiment conducted a search for charge-parity violation in decays using proton-proton collision data from 2018, analyzing around 10 billion events with b hadrons decaying into charm hadrons.
  • The flavor of the neutral D meson was determined through the charge of pions in the reconstructed decays, and an asymmetry measurement in the decays was reported, taking into account various uncertainties.
  • This research marks the first asymmetry measurement by the CMS in the charm sector and the first to use a fully hadronic final state in such analyses.
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: The aim of this randomized controlled trial (RCT) was to assess the impact of a 12-week intervention of two 20-min sessions per week, combining aerobic exercise with whole-body electromyostimulation (WB-EMS), on physical and cognitive performance in the elderly. : A total of 61 participants (age = 71 ± 5.64 years), healthy or at risk for dementia, were randomly assigned to an experimental training group (ETG, n = 33) and a control group (CON, n = 28).

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: This case study involved a 24-year-old male with an arteriovenous malformation localized in the long head of the right biceps femoris muscle, with an anterior cruciate ligament injury. The aim was to assess the effects of a five-week kinesiological protocol, which included global postural re-education and strengthening exercises focused on knee stabilization. The effectiveness of the therapeutic intervention was evaluated using Gait Analysis, clinical examination, and the SF-36 questionnaire to assess the patient's quality of life.

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Article Synopsis
  • A study evaluated a six-week visual training program to see its effects on reaction times and executive functions in high-ranking fencers.
  • Twenty-seven fencers were split into two groups: one received additional visual training (VTG) while the other did not (CG) and all were tested on reaction times before and after the training.
  • Both groups improved in reaction times, but the VTG group showed a notable enhancement in short reaction times, suggesting that the SVTA method could be beneficial for elite fencers.
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Introduction: As highlighted by the scientific literature, music therapy (MT) represents a significant non-pharmacological intervention within neurorehabilitation programs. MT offers benefits in the recovery process and enhances the quality of life for patients with neurodevelopmental disorders. A review of the literature reveals a lack of MT models focusing on real-time personalized composition using electronic music techniques.

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Lichen planus is a common pruritic inflammatory disorder of the skin with an autoimmune background. It affects < 1% of the general population. The disease has significant comorbidities that must be considered in a holistic approach.

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Brain plasticity is involved in the regulation of neural differentiation as well as in functional processes related to memory consolidation, learning, and cognition during healthy life and brain pathology. Modifications in lifestyle, like poor diet, insufficient physical exercise and cognitive stimulation are associated with an increased risk of neurodegeneration; however, there is a paucity of research regarding the impact of individual factors on dementia risk or progression. Cognitive stimulation is a group of techniques and strategies, including cognitive enrichment (CE) and cognitive training (CT), aimed to maintain or improve the functionality of cognitive abilities, such as memory, learning, cognitive flexibility, and attention.

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This comprehensive review provides insights and suggested strategies for the analysis of germline variants using second- and third-generation sequencing technologies (SGS and TGS). It addresses the critical stages of data processing, starting from alignment and preprocessing to quality control, variant calling, and the removal of artifacts. The document emphasized the importance of meticulous data handling, highlighting advanced methodologies for annotating variants and identifying structural variations and methylated DNA sites.

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Article Synopsis
  • This study examines how leisure activities throughout life influence cognitive function in aging individuals, including those with Alzheimer's disease (AD).
  • The research was conducted with participants across different cognitive states—AD, Mild Cognitive Impairment (MCI), and healthy controls—who completed a questionnaire on their leisure activities, underwent cognitive exams, and brain scans.
  • Findings suggest that social and physical activities in middle age, along with other lifestyle factors, significantly predict current cognitive ability, underscoring the importance of engaging in stimulating activities to build cognitive reserves against decline.
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Purpose: This study aimed to develop and validate the Brief Eating Self-Efficacy Scale (ESEBS-BR) in Brazilian Portuguese, addressing the lack of tools to assess eating self-efficacy beliefs in Portuguese-speaking populations.

Method: The study sought to cross-culturally adapt the scale, evaluate its internal structure, validate its reliability and validity, and explore potential associations between eating self-efficacy and eating behaviors. The cross-cultural adaptation process involved translation and back-translation, expert committees, and pre-testing.

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