"I Am Longing and Afraid to Depend on You": A Case Report on Breakdowns of Therapeutic Alliance and Interpersonal Cycles in Complex Trauma.

Background: Patients with Complex Trauma (CT) may have an impaired ability to trust others and build intimate relationships due to non-integrated representations of self and others. This sometimes leads to an oscillation between needing and fearing intimacy in their adult relationships. This dynamic can occur in the therapeutic relationship, undermining the effectiveness of therapy and affecting the mental health of both the patient and the therapist.

Polyamine Metabolism and Functions: Key Roles in Cellular Health and Disease.

The polyamines putrescine, spermidine, and spermine are polycations ubiquitously present in cells, where they exert pleiotropic functions in cellular mechanisms like proliferation, protein synthesis (through the hypusination of the transcription factor EIF5a), redox balance, autophagy, and different forms of cell death [...

Preliminary Characterization of a Novel Aerosol Jet-Printed Strain Sensor for Feasibility Assessment in a Variable Stiffness Arterial Simulator Application.

Wearable strain sensors are widespread in many fields, including the biomedical field where they are used for their stretchability and ability to be applied to non-regular surfaces. The study of the propagation speed of the pressure wave generated by the heartbeat within vessels, i.e.

Short Italian Wilkins Rate of Reading Test for repeated-measures designs in optometry and neuropsychology.

Background: The recently published New Italian version of the Wilkins Rate of Reading Test (standard Italian WRRT) was designed to measure reading speed in repeated-measures designs in research and/or clinical examinations. The test features 15 equivalent 10-line passages made up of unrelated words, adhering to the principles established by the Wilkins Rate of Reading Test in English (original WRRT).

Aim: To develop a short Italian version of the WRRT (SI-WRRT), and to determine the equivalence across the new, shorter passages of text.

Possible differences in the performances of vibration-reducing gloves when used with hammers of different sizes.

Protection provided by vibration-reducing gloves (VR) when used with impact tools can be considerably different from that measured following the ISO 10819 Standard. This paper investigates the transmissibility, at the palm level, of three different types of vibration-reducing gloves (air bubbles; gel; neoprene) and a working leather glove, while using 8 different models of electro-pneumatic hammers for chiseling rock in a limestone quarry plant. The capability to reduce the triaxial vibration as the average of all the tested hammers results limited: 12 % for both the gloves in gel and neoprene, and 7 % for the glove in air.

Evaluating the impact of gadolinium contamination on the marine bivalve Donax trunculus: Implications for environmental health.

Gadolinium (Gd), commonly used in contrast agents for medical imaging, has been detected in hospital wastewater and aquatic environments, raising environmental concerns. This study examined the accumulation and cellular impacts of Gd in the clam species Donax trunculus, commonly used as bioindicator of contamination. Gadolinium accumulation in clams increased with exposure and over time.

Riparian vegetation entraps macroplastics along the entire river course: Implications for eco-safety activities and mitigation strategies.

Macroplastic litter causes detrimental effects on freshwater biota affecting human health. Despite the significant role of rivers in transporting plastic waste, most plastics remain in fluvial ecosystems, accumulating in infrastructure, river sediment, and (riverbank) vegetated areas. However, the entrapment of plastics by riparian vegetation was overlooked, particularly in upper and middle river courses.

Braiding Fruits and Flowers as a Wish of Prosperity and Victory over Death in the Carved Festoons of Ancient Rome.

Plant motifs had a significant role in ancient cultures, with decorative, artistic, and communicative values. However, little knowledge exists of the botanical composition of festoons, widely used in Greek-Roman art. We analysed 81 festoons, exclusively from sculpture artworks, collected from 13 museums and archaeological sites in Rome (1st century BC-3rd century AD).

Comparative Approach to Performance Estimation of Pulsed Wave Doppler Equipment Based on Kiviat Diagram.

Quality assessment of ultrasound medical systems is a demanding task due to the high number of parameters to quantify their performance: in the present study, a Kiviat diagram-based integrated approach was proposed to effectively combine the contribution of some experimental parameters and quantify the overall performance of pulsed wave Doppler (PWD) systems for clinical applications. Four test parameters were defined and assessed through custom-written measurement methods based on image analysis, implemented in the MATLAB environment, and applied to spectral images of a flow phantom, i.e.

Mapping Italian high-altitude ponds.

Permanent and temporary ponds are considered peculiar ecosystems which provide important ecosystem functions, services, supporting biodiversity on small and large scales. Pond's conservation status is globally critical. Moreover, their ecological functioning and conservation status is frequently overlooked, because of the habitat small size, their seasonal occurrence and their unique appearance.

Applications of blockchain technology in peer-to-peer energy markets and green hydrogen supply chains: a topical review.

Countries all over the world are shifting from conventional and fossil fuel-based energy systems to more sustainable energy systems (renewable energy-based systems). To effectively integrate renewable sources of energy, multi-directional power flow and control are required, and to facilitate this multi-directional power flow, peer-to-peer (P2P) trading is employed. For a safe, secure, and reliable P2P trading system, a secure communication gateway and a cryptographically secure data storage mechanism are required.

Dilute suspensions of Janus rods: the role of bond and shape anisotropy.

Nanometer-sized clusters are often targeted due to their potential applications as nanoreactors or storage/delivery devices. One route to assemble and stabilize finite structures consists of imparting directional bonding patterns between the nanoparticles. When only a portion of the particle surface is able to form an inter-particle bond, finite-size aggregates such as micelles and vesicles may form.

Isotopic signature of plutonium accumulated in cryoconite on glaciers worldwide.

Glaciers are recognized as repositories for atmospheric pollutants, however, due to climate change and enhanced melting rates, they are rapidly transitioning from being repositories to secondary sources of such apollutants. Artificial radionuclides are one of the pollutants found on glaciers that efficiently accumulate onto glacier surfaces within cryoconite deposits; a dark, often biogenic sediment. This work provides information about the accumulation, distribution and sources of plutonium (Pu) isotopes in cryoconite samples from glaciers worldwide.

Physical and chemical properties and degradation of MAPbBr films on transparent substrates.

To date, the potential exploitation of hybrid organic-inorganic perovskites (HOIPs) in photovoltaic technologies has been significantly hampered by their poor environmental stability. HOIP degradation can be triggered by conventional operational environments, with excessive heating and exposure to oxygen and moisture significantly reducing the performances of HOIP-based solar cells. An imperative need emerges for a thorough investigation on the impact of these factors on the HOIP stability.

Unveiling the hidden players: noncoding RNAs orchestrating polyamine metabolism in disease.

Polyamines (PA) are polycations with pleiotropic functions in cellular physiology and pathology. In particular, PA have been involved in the regulation of cell homeostasis and proliferation participating in the control of fundamental processes like DNA transcription, RNA translation, protein hypusination, autophagy and modulation of ion channels. Indeed, their dysregulation has been associated to inflammation, oxidative stress, neurodegeneration and cancer progression.

Assessing teratogenic risks of gadolinium in freshwater environments: Implications for environmental health.

Gadolinium (Gd) is among the rare earth elements extensively utilized in both industrial and medical applications. The latter application appears to contribute to the rise in Gd levels in aquatic ecosystems, as it is excreted via urine from patients undergoing MRI scans and often not captured by wastewater treatment systems. The potential environmental and biological hazards posed by gadolinium exposure are still under investigation.

Passive biomonitoring of airborne microplastics using lichens: A comparison between urban, natural and protected environments.

Currently, natural and urban ecosystems are affected by different types of atmospheric deposition, which can compromise the balance of the environment. Plastic pollution represents one of the major threats for biota, including lichens. Epiphytic lichens have value as bioindicators of environmental pollution, climate change, and anthropic impacts.

Evaluation of the Antioxidant Capacity of 3,3-Disubstituted-3H-benzofuran-2-one Derivatives in a Cellular Model of Neurodegeneration.

Oxidative stress represents a hallmark for many degenerative pathologies of the Central Nervous System. Throughout life, the constant pressure of noxious stimuli and/or episodes of traumatic events may expose the brain to a microenvironment where the non-balanced reactive oxygen species inevitably lead to neuronal loss and cognitive decline. HO-1, a 32 kDa heat-shock protein catalyzing the degradation of heme into carbon monoxide (CO), iron and biliverdin/bilirubin is considered one of the main antioxidant defense mechanisms playing pivotal roles in neuroprotection.

Conceptual study of a new instrument for dynamic neutron scattering measurements-The modulated intensity with diffraction analysis spectrometer (MIDAS).

Dynamic neutron scattering probes unique nanoscale dynamics via measurement of energy exchanged between a sample and the neutrons. The two spectrometers that investigate processes with characteristic times around a nanosecond are backscattering (BS) and neutron spin-echo (NSE). We present a new method for measuring dynamics using an oscillating cosine-like energy-distribution neutron-package at the sample and measure solely the portion scattered into the elastic line.

Trimetazidine Improves Mitochondrial Dysfunction in SOD1 Cellular Models of Amyotrophic Lateral Sclerosis through Autophagy Activation.

Amyotrophic Lateral Sclerosis (ALS) is considered the prototype of motor neuron disease, characterized by motor neuron loss and muscle waste. A well-established pathogenic hallmark of ALS is mitochondrial failure, leading to bioenergetic deficits. So far, pharmacological interventions for the disease have proven ineffective.

Predicting Online Behavioural Responses to Transcranial Direct Current Stimulation in Stroke Patients with Anomia.

Anomia, or difficulty naming common objects, is the most common, acquired impairment of language. Effective therapeutic interventions for anomia typically involve massed practice at high doses. This requires significant investment from patients and therapists.

Sensitivity and Specificity of Qualitative Visual Field Tests for Screening Visual Hemifield Deficits in Right-Brain-Damaged Stroke Patients.

A timely detection of visual hemifield deficits (VHFDs; hemianopias or quadrantanopias) is critical for both the diagnosis and treatment of stroke patients. The present study determined the sensitivity and specificity of four qualitative visual field tests, including face description, confrontation tests (finger wiggle), and kinetic boundary perimetry, to screen large and dense VHFDs in right-brain-damaged (RBD) stroke patients. Previously, the accuracy of qualitative visual field tests was examined in unselected samples of patients with heterogeneous aetiology, in which stroke patients represented a very small fraction.

Comparative genomics provides insights into molecular adaptation to hypermetamorphosis and cantharidin metabolism in blister beetles (Coleoptera: Meloidae).

Blister beetles (Coleoptera: Meloidae) are currently subdivided into three subfamilies: Eleticinae (a basal group), Nemognathinae, and Meloinae. These are all characterized by the endogenous production of the defensive terpene cantharidin (CA), whereas the two most derived subfamilies show a hypermetamorphic larval development. Here, we provide novel draft genome assemblies of five species sampled across the three blister beetle subfamilies (Iselma pallidipennis, Stenodera caucasica, Zonitis immaculata, Lydus trimaculatus, and Mylabris variabilis) and performed a comparative analysis with other available Meloidae genomes and the closely-related canthariphilous species (Pyrochroa serraticornis) to disclose adaptations at a molecular level.