30 results match your criteria: "University of Rennes1[Affiliation]"

Current approach to hemochromatosis.

Blood Rev

July 2008

Liver Disease Unit, Liver Research Unit Inserm U-522, IFR 140, University of Rennes1, Hemochromatosis Reference Center, Laboratory of Molecular Genetics, University Hospital Pontchaillou, Rennes, France.

Iron overload diseases of genetic origin are an ever changing world, due to major advances in genetics and molecular biology. Five major categories are now established: HFE-related or type1 hemochromatosis, frequently found in Caucasians, and four rarer diseases which are type 2 (A and B) hemochromatosis (juvenile hemochromatosis), type 3 hemochromatosis (transferrin receptor 2 hemochromatosis), type 4 (A and B) hemochromatosis (ferroportin disease), and a(hypo)ceruloplasminemia. Increased duodenal iron absorption and enhanced macrophagic iron recycling, both due to an impairment of hepcidin synthesis, account for the development of cellular excess in types 1, 2, 3, and 4B hemochromatosis whereas decreased cellular iron egress is involved in the main form of type 4A) hemochromatosis and in aceruloplasminemia.

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A unified representation of findings in clinical radiology using the UMLS and DICOM.

Int J Med Inform

September 2008

EA 3888, LIM, Faculty of Medicine, IFR 140, University of Rennes1, 2 avenue du Professeur Léon Bernard, 35000 Rennes, France.

Article Synopsis
  • * An automated mapping process was conducted to link findings in bone and joint radiology to UMLS, revealing that 45% of findings lacked corresponding UMLS concepts, leading to the development of a generic DICOM-SR template for disorganized data.
  • * The study concludes that while a semi-automated method can represent medical findings using UMLS and DICOM-SR, the UMLS needs to expand its coverage to better serve the needs of radiology by including more relevant concepts and terms.
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The representations of findings in clinical radiology are heterogeneous. Motivations for developing a unified representation include the semantic integration of medical reports based on DICOM-SR(Digital Image Communication in Medicine Structured Reporting), bibliographic databases in the context of evidence-based medicine, and teaching resources. In this work, we propose a unified representation integrating the representations of findings in the UMLS, the GAMUTS in Radiology and the DICOM-SR.

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Digitalization of audiovisual resources and network capability offer many possibilities which are the subject of intensive work in scientific and industrial sectors. Indexing such resources is a major challenge. Recently, the Motion Pictures Expert Group (MPEG) has developed MPEG-7, a standard for describing multimedia content.

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Mild cognitive impairment: a treatment at last?

Lancet Neurol

November 2004

Laboratory of Clinical and Experimental Pharmacology, Centre Mémoire Ressource Recherche de Bretagne, Faculty of Medicine University of Rennes1, France.

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