Heavy metals and metalloid contamination and risk evaluation in the surface sediment of the Bakkhali River estuary in Bangladesh.

Current state of contamination and subsequent risk of contaminated sediment of a tidal river of Bangladesh was evaluated in the present study. Sediment samples were collected from five locations in the tributary of Bakkhali River estuary during summer (April) and winter (December) season, 2020. Collected samples were processed using standard protocol and the content of heavy metals (Cd, Cr, Cu, Pb and Zn) and metalloid (As), were analyzed by the Flame Atomic Absorption Spectrometer.

silver chloride nanoparticles and mediated silver/silver chloride nanoparticles inhibit human hepatocellular and lung cancer cell lines.

Recently, we have reported that biogenic silver/silver chloride nanoparticles from (-AgCl-NPs) and (-Ag/AgCl-NPs) inhibited different cancer cells by inducing apoptosis and several genes alteration. Here for the first time, we assessed the effects of these two nanoparticles on human lung (A549) and hepatocellular (SMMC-7721) carcinoma cell lines. AgCl-NPs and -Ag/AgCl-NPs inhibited A549 cell growth with IC values of 22.

An immunoinformatics approach for a potential NY-ESO-1 and WT1 based multi-epitope vaccine designing against triple-negative breast cancer.

Breast cancer emerges as one of the most prevalent malignancies in women, its incidence showing a concerning upward trend. Among the diverse array of breast cancer subtypes, triple-negative breast cancer (TNBC) assumes notable significance, due to lack of estrogen, progesterone, and HER-2 receptors. More focus has to be placed on creating effective therapy due to the high prevalence and rising incidence of TNBC.

Deciphering the complete genome sequence of multidrug-resistant strain Hakim RU_GHWS isolated from ladies' hall sewage water in Bangladesh.

This report details the genome sequence of strain Hakim RU_GHWS, isolated from sewage water. The assembled genome comprises 5.022 Mb with 77.

Numerical evaluation and optimization of high sensitivity CuCdSnSe photodetector.

Copper cadmium tin selenide (CuCdSnSe) based photodetector (PD) has been explored with the solar cell capacitance simulator (SCAPS-1D). Herein, cadmium sulfide (CdS) and molybdenum disulfide (MoS) are used as a window and back surface field (BSF) layers, respectively. The physical attributes, such as width, carrier density and bulk defects have been adjusted to attain the optimal conditions.

Heterologous expression, characterisation and 3D-structural insights of GH18 chitinases derived from sago palm (Metroxylon sagu).

Although plants don't have chitins, they produce chitinases to protect themselves from biotic and abiotic stressors. There are two forms of chitinases found in organisms: glycosyl hydrolase 18 (GH18) and 19 (GH19) families. Plant GH19 chitinases are well known for their role in protecting against pathogens, but the roles of GH18 chitinases have not been fully elucidated.

Computational screening and molecular docking of compounds from Traditional Chinese Medicine (TCM) by targeting DNA topoisomerase I to design potential anticancer drugs.

Each year thousands of people suffer across the globe due to higher cancer incidence and mortality rates. Additionally, the treatment option for cancer patients is also costly, and often cancer drugs suffer from lower efficacy with more side effects. The DNA topoisomerase can function as an established cancer target because Human Topoisomerase (Top1) regulates genetic transcription during the post-mitotic phase and plays a critical role in DNA supercoiling during replication and repair.

Management strategies of translocated pondweed Monochoria hastata and its ecological and economic impacts.

Understanding the impacts of, and options for, controlling invasive species is crucial to their management. Wetlands are a widely invaded ecosystem, since dispersal of aquatic species is facilitated by seasonal flooding. This study evaluated the effects of the translocated pondweed Monochoria hastata on fish and rice production in two wetlands of Bangladesh over six years (2017-2022).

Megacity solid waste disposal suitability mapping in Dhaka, Bangladesh: an integrated approach using remote sensing, GIS and statistics.

Selecting suitable Megacity Solid Waste Disposal (MSWD) sites is a challenging task in densely populated deltas of developing countries, exacerbated by limited public awareness about waste management. One of the major environmental concerns in Dhaka City, the world's densest megacity, is the presence of dumps close to surface water bodies resources. This study employed the Geographic Information System (GIS)-Analytic Hierarchy Process (AHP) framework to integrate geomorphological (slope and flow accumulation), geological (lithological and lineament), hydrogeological (depth to groundwater table and surface waterbody), socioeconomic (Land use land cover, distance to settlement, road, and airport), and climatological (wind direction) determinants, coupled by land-use and hydro-environmental analyses, to map optimal dumps (MSWD sites.

Correction: A computational study of the thortveitite structure of zinc pyrovanadate, ZnVO, under pressure.

[This corrects the article DOI: 10.1039/D3RA02426A.].

Identification of Hub of the Hub-Genes From Different Individual Studies for Early Diagnosis, Prognosis, and Therapies of Breast Cancer.

Breast cancer (BC) is a complex disease, which causes of high mortality rate in women. Early diagnosis and therapeutic improvements may reduce the mortality rate. There were more than 74 individual studies that have suggested BC-causing hub-genes (HubGs) in the literature.

Some biological aspects of chacunda gizzard shad, (Hamilton, 1822) from the Bay of Bengal, Bangladesh.

is a commercial fish species in the market and is usually consumed in fresh, smoked, and dried forms. This study investigated the population structure, length-weight relationships (LWR), condition factor ( ), size at sexual maturity ( ), and breeding season of in the Bay of Bengal, Bangladesh, using the data collected from January to December 2020. A total of 1061 individuals were collected in the sampling period with the help of fishers.

Functional characterization and biotechnological applications of exopolysaccharides produced by newly isolated Enterococcus hirae MLG3-25-1.

This study investigated the potential applications of Enterococcus hirae MLG3-25-1 exopolysaccharides (EPS), with a focus on their isolation, identification, production, and functional characteristics. After the bacterial strain was cultured in De Man-Rogosa-Sharpe (MRS) medium containing 1% glucose at 37 °C, the EPS was refined, and the highest yield of 0.85 mg/mL was achieved at the 24-h incubation period.

Common molecular and pathophysiological underpinnings of delirium and Alzheimer's disease: molecular signatures and therapeutic indications.

Background: Delirium and Alzheimer's disease (AD) are common causes of cognitive dysfunction among older adults. These neurodegenerative diseases share a common and complex relationship, and can occur individually or concurrently, increasing the chance of permanent mental dysfunction. However, the common molecular pathophysiology, key proteomic biomarkers, and functional pathways are largely unknown, whereby delirium is superimposed on AD and dementia.

Genome-wide identification and characterization of FORMIN gene family in potato (Solanum tuberosum L.) and their expression profiles in response to drought stress condition.

Formin proteins, characterized by the FH2 domain, are critical in regulating actin-driven cellular processes and cytoskeletal dynamics during abiotic stress. However, no genome-wide analysis of the formin gene family has yet to be conducted in the economically significant plant potato (Solanum tuberosum L.).

An approach to integrated management of diabetes in tuberculosis patients: Availability and readiness of the health facilities of Bangladesh.

Background: Comorbidity of diabetes mellitus and tuberculosis (TB) is a major public health concern in low- and middle-income countries including Bangladesh. An integrated approach is required for adequate management of diabetes mellitus and TB. The objective of the present study was to investigate the availability and readiness of the TB care centers of Bangladesh toward diabetic patients' management.

Numerical Expedition on the Potential of AgBiS-Based Thin Film Solar Cells Employing Different Carrier Transport Layers.

In this study, a photovoltaic (PV) device has been developed by using AgBiS as the key material. The simulation of the photovoltaic cell has been performed using the SCAPS-1D simulator to analyze the impact of each layer. The design incorporates three window layers, CdS, InS, and ZnSe, alongside six familiar compounds, AlSb, CuGaSe (CGS), CuS, MoS, SbS, and WSe, as the back surface field (BSF) layers.

Integrated Gene Expression Data-Driven Identification of Molecular Signatures, Prognostic Biomarkers, and Drug Targets for Glioblastoma.

Glioblastoma (GBM) is a highly prevalent and deadly brain tumor with high mortality rates, especially among adults. Despite extensive research, the underlying mechanisms driving its progression remain poorly understood. Computational analysis offers a powerful approach to explore potential prognostic biomarkers, drug targets, and therapeutic agents for GBM.

Soil pollution and elemental sources along Barapukuria coal mine, Bangladesh: Implications for eco-environmental and health risk assessment.

For the first time, different pollution indices and a receptor model have been used to quantify eco-environmental and health risk assessments as well as identify the sources of potentially toxic elements in soil along the Barapukuria Coal Mine (BCM). Individual indices include enrichment and contamination factors showing the soil samples are moderately to highly contaminated by arsenic, cobalt, chromium, copper, lead, and zinc and heavily contaminated by sulfur. According to the geo-accumulation index, there is significant pollution with arsenic (1.

Coalbed methane reservoir properties assessment and 3D static modeling for sweet-spot prediction in Dahebian block, Liupanshui Coal field, Guizhou Province, southwestern China.

Guizhou Province has many multi-layer, thin-thick coal seams; however, complex geology, incomplete reservoir characterization, and sweet-spot selection technology prevent large-scale coalbed methane (CBM) development. This study evaluates the CBM reservoir properties within the Dahebian block using logging data, coal sample analysis, and well-testing data and develops a 3D static reservoir properties model to analyze their spatial and vertical propagation. A sweet spot evaluation model was established using a multi-level fuzzy method based on 9 parameters extracted from a 3D static reservoir properties model.

Salinity negatively correlates with the production and immunity of chicken: A molecular insight for food security and safety issues.

Salinity intrusion into the freshwater system due to climate change and anthropogenic activities is a growing global concern, which has made humans and domesticated animals more susceptible to diseases, resulting in less productivity. However, the effects of salinity on domesticated and wild birds, especially in terms of production and immunity, have not been fully elucidated yet. Therefore, this study was designed to examine the effects of salinity on the production and immunity of birds and the mechanisms by which immunity is compromised.

Healthcare services access challenges and determinants among persons with disabilities in Bangladesh.

Persons with disabilities in LMICs facing numerous challenges in accessing essential healthcare services. However, this understanding is lacking so far in LMICs and Bangladesh. This study aimed to explore the pattern and determinants of healthcare services access among persons with disabilities in Bangladesh.