333 results match your criteria: "University of Queensland Medical School[Affiliation]"

Spinal cord sarcoidosis, an uncommon manifestation of neurosarcoidosis, presents diagnostic and therapeutic challenges because the condition is rare and has diverse clinical manifestations that can mimic other conditions such as multiple sclerosis and neuromyelitis optica spectrum disorder. A middle-aged African American female with a history of idiopathic intracranial hypertension and hydrocephalus with ventriculoperitoneal shunt presented with progressive, predominantly left-sided gait instability, weakness, and paresthesia. Cerebrospinal fluid showed lymphocytosis, red blood cells, elevated oligoclonal bands, and elevated kappa free light chains, concerning for multiple sclerosis.

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Patients and providers vary in how they describe common otolaryngology-related complaints. These differences can lead to miscommunication and frustration that may affect patient outcomes and satisfaction. The aim of this cross-sectional survey-based study was to explore the differences in migraine symptom selection by otolaryngology patients and clinicians.

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Happy Holidays and Happy New Year.

Ochsner J

January 2024

Director of Clinical School and Professor, The University of Queensland Medical School, Ochsner Clinical School, New Orleans, LA; Editor-in-Chief, Ochsner Journal.

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The Disappearance of Black Men From Medicine: A Consequence of Racism and the Flexner Report.

Ochsner J

January 2024

Department of Rheumatology, Ochsner Clinic Foundation, New Orleans, LA and The University of Queensland Medical School, Ochsner Clinical School, New Orleans, LA.

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The Xavier Ochsner College of Medicine - "The Time Is Always Right To Do What Is Right".

Ochsner J

January 2024

Global Health and Education, Ochsner Clinic Foundation, New Orleans, LA and The University of Queensland Medical School, Ochsner Clinical School, New Orleans, LA.

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Despite the substantial expenditures on health care in the United States, persistent underperformance in health system metrics necessitates innovative approaches to address complex patient needs. The MedVantage Clinic in New Orleans, Louisiana, offers a regionally tailored, value-based primary care model targeting patients with high social and medical needs. This study provides an evaluation of the efficacy of the MedVantage Clinic in improving the cost of care and service utilization for this population.

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Compassionate access to virus-specific T cells for adoptive immunotherapy over 15 years.

Nat Commun

December 2024

Queensland Immunology Research Centre, Infection and Inflammation Program, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.

Adoptive T-cell immunotherapy holds great promise for the treatment of viral complications in immunocompromised patients resistant to standard anti-viral strategies. We present a retrospective analysis of 78 patients from 19 hospitals across Australia and New Zealand, treated over the last 15 years with "off-the-shelf" allogeneic T cells directed to a combination of Epstein-Barr virus (EBV), cytomegalovirus (CMV), BK polyomavirus (BKV), John Cunningham virus (JCV) and/or adenovirus (AdV) under the Australian Therapeutic Goods Administration's Special Access Scheme. Most patients had severe post-transplant viral complications, including drug-resistant end-organ CMV disease, BKV-associated haemorrhagic cystitis and EBV-driven post-transplant lymphoproliferative disorder.

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Objective: Poor interdisciplinary team communication is a known barrier to increasing inpatient mobility. Understanding why and how clinicians from different disciplines communicate about mobility would help inform communication improvements. This qualitative interview study aimed to describe and explore clinician perceptions about written mobility communication, and perceived barriers and enablers to this communication.

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So What?

Ochsner J

January 2024

Department of Anesthesiology and Perioperative Medicine, Ochsner Clinic Foundation, New Orleans, LA and The University of Queensland Medical School, Ochsner Clinical School, New Orleans, LA.

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Autumn Is Coming.

Ochsner J

January 2024

Director of Clinical School and Professor, The University of Queensland Medical School, Ochsner Clinical School, New Orleans, LA; Editor-in-Chief, Ochsner Journal.

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Article Synopsis
  • Obesity, defined as a body mass index ≥30 kg/m², is widespread in the U.S. and linked to various health risks; the study focuses on its effect on the need for instrumental vaginal delivery during childbirth.
  • This retrospective study analyzed data from women in active labor to evaluate the association of maternal obesity with the incidence of instrumental deliveries, using effect size measures for better accuracy compared to frequentist tests.
  • The findings indicated that while maternal obesity was more common in women with certain health issues, it did not have a significant clinical impact on the need for instrumental delivery.
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Achondroplasia can result in many skeletal manifestations, and degenerative osteoarthritis can develop in patients with achondroplasia. Morphologic changes to both the humerus and glenoid-short humeri with patulous metaphyses and a medialized glenoid-can cause challenges that must be overcome to achieve a successful surgical result in a patient with shoulder dysfunction. Because patients with achondroplasia have near-normal life expectancies, the operative shoulder must be functional as well as quite durable in the long term.

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Article Synopsis
  • - A 51-year-old woman who had prior cervical spine surgery faced complications due to hardware failure, leading to an esophageal perforation after the removal of surgical instruments.
  • - An initial attempt to repair the laceration using a rotational flap was unsuccessful, which led to the need for a more complex surgery involving a radial forearm free flap (RFFF) for esophageal reconstruction.
  • - The report emphasizes that treating persistent esophageal perforations is challenging and highlights considerations for choosing between different surgical techniques based on factors like defect size and wound condition.
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Article Synopsis
  • The review highlights the importance of physical activity guidelines and how continuous exercise leads to beneficial molecular adaptations, improving health outcomes.
  • It emphasizes cardiorespiratory fitness and resistance training as key factors in reducing mortality rates and enhancing overall quality of life.
  • The text calls for personalized exercise programs and innovative strategies to encourage community engagement and increased physical activity participation, despite ongoing challenges with cardiovascular diseases and cancer risk.
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Frailty scores impact the outcomes of urgent carotid interventions in acute stroke patients: A comprehensive analysis of risk and prognosis.

J Vasc Surg

December 2024

Section of Vascular/Endovascular Surgery, Department of Surgery, Ochsner Clinic Foundation, New Orleans, LA; The University of Queensland Medical School, Ochsner Clinical School, New Orleans, LA. Electronic address:

Background: Carotid artery disease is an important cause of ischemic strokes. Patient selection for urgent carotid interventions (ie, urgent carotid endarterectomy [uCEA] and urgent carotid artery stenting [uCAS]) performed within 2 weeks of an event during the index hospitalization is based primarily on a patient's overall health and risk profile. Identifying high-risk patients remains a challenge.

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The impact of surgical complications on obstetricians' and gynecologists' well-being and coping mechanisms as second victims.

Am J Obstet Gynecol

January 2025

Queensland Centre for Gynaecological Cancer Research, Faculty of Medicine, Centre for Clinical Research, University of Queensland, Brisbane, Australia. Electronic address:

Background: Obstetrics and gynecology surgery is becoming increasingly complex because of an aging population with increasing rates of medical comorbidities and obesity. Complications are therefore common, and not only impact the patient but can also cause distress to the obstetrics and gynecology surgeon as a "second victim."

Objective: This study aimed to describe and quantify the range of effects of complications on obstetrics and gynecology surgeons, and assess sociodemographic, clinician, and practice factors associated with such impact.

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Background: Delirium has conventionally been considered a disorder of consciousness. Alertness and arousal are used as surrogates in clinical practice but are insufficient for the purposes of a more dimensional assessment of consciousness. We present a process of development and validation of candidate measures of phenomenal consciousness that could be applied to the diagnosis of delirium.

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T staging esophageal tumors with x rays.

Optica

April 2024

Department of Medical Physics and Biomedical Engineering, University College London, London WC1E 6BT, UK.

With histopathology results typically taking several days, the ability to stage tumors during interventions could provide a step change in various cancer interventions. X-ray technology has advanced significantly in recent years with the introduction of phase-based imaging methods. These have been adapted for use in standard labs rather than specialized facilities such as synchrotrons, and approaches that enable fast 3D scans with conventional x-ray sources have been developed.

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Salvage revisions of atlantoaxial (AA) joint complex posterior segmental instrumented fusion constructs require careful individualized planning to prevent occipital extension. In this case report, we describe the use of bilateral intrafacet spacer placement as a mobility-sparing bailout option for the revision surgery. A 64-year-old male with a history of diffuse idiopathic skeletal hyperostosis, extremely limited baseline cervical mobility, and prior AA posterior segmental instrumented fusion presented with increasing pain at his 6-month follow-up.

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Prolonged fever for more than a week or fever of unknown origin in pediatric patients with or without soft tissue infection should raise suspicion for infection. A 10-year-old female presented to urgent care with a "bug bite" on the left ring finger, cough, and 2 to 3 days of low-grade fever. Ten days later, her symptoms progressed to soft tissue swelling of the left elbow without fracture on radiograph.

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REPLACING THE CHAOS.

Ochsner J

January 2024

Director of Clinical School and Professor, The University of Queensland Medical School, Ochsner Clinical School, New Orleans, LA; Editor-in-Chief, Ochsner Journal.

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While the connection between alcohol and risky behavior is well known, a clear correlation between alcohol misuse and contracting sexually transmitted infections (STIs) has not been determined. The 4-question CAGE questionnaire-the acronym stands for attitudes and activities related to alcohol use-is often administered at primary care annual visits to screen patients for alcohol abuse. This study assessed the relationship between CAGE scores and STI results to determine if the CAGE questionnaire could help determine the need for STI screening at annual visits.

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Stumped by a Case of Appendicitis After Appendectomy.

Ochsner J

January 2024

The University of Queensland Medical School, Ochsner Clinical School, New Orleans, LA.

Stump appendicitis-a rare, delayed complication of appendectomy-is most commonly managed with surgical exploration and stump appendectomy. Conservative management in the pediatric population is poorly characterized in the literature. We report a case of a 10-year-old male who was diagnosed with stump appendicitis and initially treated nonoperatively.

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Buprenorphine/naloxone (Suboxone) is widely considered the first-line treatment for opioid use disorder (OUD), which causes significant morbidity and mortality in the United States, but prior to 2023, practitioners interested in prescribing buprenorphine/naloxone for OUD needed a special Drug Enforcement Administration certification (the X-Waiver) that imposed a patient cap and other limitations. The Consolidated Appropriations Act of 2023 considerably decreased the restrictions on prescribing practitioners. Buprenorphine/naloxone can now be prescribed like any other prescription opioid, excluding methadone.

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