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3,689 results match your criteria: "University of Puerto Rico Mayagüez Campus[Affiliation]"
ChemMedChem
December 2024
University of Puerto Rico Rio Piedras: Universidad de Puerto Rico Recinto de Rio Piedras, Chemistry, 17 University Avenue, 00925, San Juan, UNITED STATES OF AMERICA.
Deferasirox (Def), an orally administered iron-chelating drug, has drawn significant interest in repurposing for anticancer application due to the elevated Fe demand by cancer cells. But there are also concerns about its severe off target health effects. Herein Cu(II) binding is studied as a potential off target interaction.
View Article and Find Full Text PDFSupport Care Cancer
December 2024
Physical Therapy Program, Medical Science Campus, University of Puerto Rico, P.O. Box 365967, San Juan, Puerto Rico, 00936-5067, USA.
Purpose: Compare the effects of low-intensity and moderate-intensity exercise on physical functioning in breast cancer survivors.
Methods: Women aged 50 + years and post-primary treatment for stage 0 to III breast cancer were randomly assigned to a 6-month low-intensity (LIG) or moderate-intensity (MIG) exercise group. Participants were instructed to walk (low- or moderate-intensity) for 30 min five days a week, followed by flexibility exercises, and do strengthening and balance exercises twice weekly.
Cureus
November 2024
Department of Ophthalmology, School of Medicine, Medical Sciences Campus, University of Puerto Rico, San Juan, PRI.
Giant conjunctival cysts, though rare, can cause significant discomfort and functional impairment due to their size as well as their potential for rupture and recurrence. We report the case of a 51-year-old female who presented with a recurrent giant conjunctival cyst in her left eye, experiencing considerable discomfort and pain upon eye movement. The cyst, located in the left eye, had previously recurred after surgical excision, though visual acuity remained 20/20 bilaterally.
View Article and Find Full Text PDFAm J Otolaryngol
December 2024
School of Medicine Medical Sciences Campus, Otolaryngology-Head and Neck Surgery Section, University of Puerto Rico, Puerto Rico.
Objectives: Airway compromise in neck cancer patients with distorted anatomy has been a challenge for head and neck surgeons. To the best of our knowledge, the use of ultrasound has not been reported as an adjunct prior to an awake urgent tracheostomy in these types of patients. Our main objective is to provide an additional tool for identification of vital neck structures in preparation for an awake tracheostomy.
View Article and Find Full Text PDFNpj Ment Health Res
December 2024
University of Puerto Rico, Medical Sciences Campus, San Juan, Puerto Rico.
Climate change is disproportionately impacting youth mental health around the world. Using a Community-Based Participatory approach, three universities (one in South Carolina and two in Puerto Rico) partnered after the devastation of Hurricane Maria in 2017. We offered culturally and linguistically tailored trauma and disaster-informed mental health awareness training (e.
View Article and Find Full Text PDFHereditas
December 2024
Facultad de Ciencias Biológicas, Departamento de Biología Celular y Genética, Universidad Autónoma de Nuevo León, San Nicolás de los Garza, Nuevo León, México.
Background: Breast cancer is the most prevalent cancer among women worldwide. Most breast cancer-related deaths result from metastasis and drug resistance. Novel therapies are imperative for targeting metastatic and drug-resistant breast cancer cells.
View Article and Find Full Text PDFAm J Clin Nutr
December 2024
Department of Nutrition, Gillings School of Global Public Health and School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Scientists from diverse backgrounds are underrepresented in academia. This lack of diversity impedes scientific discovery and innovation. Underrepresented (UR) scientists tend to conduct research on issues relevant to underrepresented populations, including chronic disease prevention and management, and health disparities.
View Article and Find Full Text PDFImportance: Classification of persons with long COVID (LC) or post-COVID-19 condition must encompass the complexity and heterogeneity of the condition. Iterative refinement of the classification index for research is needed to incorporate newly available data as the field rapidly evolves.
Objective: To update the 2023 research index for adults with LC using additional participant data from the Researching COVID to Enhance Recovery (RECOVER-Adult) study and an expanded symptom list based on input from patient communities.
Int J Pharm
December 2024
Pharmacogenomics (PGx) Laboratory, University of Puerto Rico, Medical Sciences Campus, San Juan, PR, 00936, United States; Department of Pharmaceutical Sciences, School of Pharmacy, University of Puerto Rico - Medical Sciences Campus, San Juan, PR 00936, United States. Electronic address:
Over the next decade, Precision Medicine (PM) is poised to become the standard of care in pharmaceutical therapy, necessitating a fundamental transformation in the design and development of innovative custom-made drug products. To date, a comprehensive review linking PM with practical personalized drug formulations is missing. This review attempts to provide an overview of state-of-the-art formulation approaches capable of translating PM evaluation and resulting recommendations (clinical research) into tailored drug products (non-clinical research) for real-world patients.
View Article and Find Full Text PDFJ Dent Educ
December 2024
Department of Instruction, Kornberg School of Dentistry, Philadelphia, Pennsylvania, USA.
Purpose/objectives: This study addresses persistent gender disparities in leadership roles in academic dentistry. The objectives were to identify the challenges and barriers to leadership that women face in general and during the COVID-19 pandemic, as well as to describe resources they need to reach their leadership potential.
Methods: The American Dental Education Association Section on Women in Leadership (WIL), gathered survey data concerning leadership challenges and faculty development needs.
Objectives: The specific aims of the project are: (1) Examine the impact of COVID-19 on pregnancy experiences and outcomes; (2) Examine the mental health impact of COVID-19 in pregnant women and mothers of children 12 months or younger; (3) Identify risk and protective factors among this population in Puerto Rico.
Methods: Participants were recruited from the Puerto Rico Team for Exploring Contamination Threats (PROTECT) Superfund Program, which is composed of pregnant women and mothers from the northern karst region of Puerto Rico. The research had a mixed methods approach with a quantitative survey (n = 184) and qualitative interviews (n = 10); data collection was done in virtual mode.
P R Health Sci J
December 2024
Third-year medical student at the University of Puerto Rico, Medical Sciences Campus, San Juan, Puerto Rico.
This is the case of a 22-year-old female who arrived at our institution after experiencing refractory insomnia, disorganized behavior, inappropriate laughter, and anorexia. Upon admission, a physical examination revealed mutism, irritability, and visual hallucinations. Infectious, metabolic, and other, alternative, causes for the presenting symptoms were excluded.
View Article and Find Full Text PDFP R Health Sci J
December 2024
University of Puerto Rico Comprehensive Cancer Center, Cancer Control and Population Sciences Division, San Juan, Puerto Rico.
Objective: Evaluate the relationship between diabetes and hypertension and COVID-19 booster uptake.
Methods: Members of the Community Outreach Group of the Puerto Rico Community Engagement Alliance Against COVID-19 Disparities (PR-CEAL) administered a survey at 229 community events between November 2021 and May 2023. Information on 2,145 participants' sociodemographic information and chronic disease diagnoses was gathered.
P R Health Sci J
December 2024
Section of Neurosurgery, Department of Surgery, University of Puerto Rico, Medical Sciences Campus, San Juan, Puerto Rico.
Objective: The epidemiology of meningiomas for patients with Hispanic ethnicity is mainly unknown beyond a few studies. Evidence supporting the ethnic influence over meningioma World Health Organization (WHO) grade is limited. This study aimed to investigate a Hispanic population in Puerto Rico with intracranial meningiomas regarding the WHO grade.
View Article and Find Full Text PDFP R Health Sci J
December 2024
University of Puerto Rico, Río Piedras Campus, San Juan, Puerto Rico.
The abuse of psychoactive substances poses a critical public health challenge in Puerto Rico, with far-reaching implications for both individuals and society as a whole. This article provides a comprehensive overview of the patterns and trends associated with drug abuse in Puerto Rico, focusing on alcohol, tobacco, cannabis, benzodiazepines, opioids, and methadone. Recent statistics reveal a concerning increase in substance abuse, particularly among young adults.
View Article and Find Full Text PDFJ Proteome Res
December 2024
Department of Biotechnology, Birla Institute of Technology and Science Pilani (BITS Pilani) - Dubai Campus, Academic City, Dubai, P.O. Box 345055, United Arab Emirates.
Metabolic rewiring is required for cancer cells to survive in harsh microenvironments and is considered to be a hallmark of cancer. Specific metabolic adaptations are required for a tumor to become invasive and metastatic. Cell division and metabolism are inherently interconnected, and several cell cycle modulators directly regulate metabolism.
View Article and Find Full Text PDFJ Affect Disord
December 2024
Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA. Electronic address:
Background: Bipolar disorder (BD) presents with a wide range of symptoms that vary among relatives, casting doubt on categorical illness models. To address this uncertainty, we investigated the heritability and genetic relationships between categorical and dimensional models of BD in a family sample.
Methods: This retrospective study included participants (n = 397 Females, n = 329 Males, mean age 47 yr) in the Amish-Mennonite Bipolar Genetics (AMBiGen) study from North and South America that were assigned categorical mood disorder diagnoses ("narrow" or "broad") by structured psychiatric interview and completed the Mood Disorder Questionnaire (MDQ), which assesses lifetime history of manic symptoms and associated impairment.
Lancet Glob Health
January 2025
Lancet Countdown, University College of London, London, UK.
Arch Dermatol Res
December 2024
Department of Dermatology, University of Texas Southwestern Medical Center, 5939 Harry Hines Blvd POBII, Dallas, TX, HQ3.315, 75235, USA.
Cureus
November 2024
Department of Ophthalmology, School of Medicine, Medical Sciences Campus, University of Puerto Rico, San Juan, PRI.
This study presents two cases of idiopathic anterior scleritis in young female patients, one of whom progressed to necrotizing scleritis. Both cases posed significant diagnostic challenges and ultimately required immunomodulatory therapy after their respective inadequate responses to the initial standard treatments. Despite comprehensive laboratory evaluations, no underlying systemic etiology was identified in either patient.
View Article and Find Full Text PDFEur Phys J C Part Fields
December 2024
A search is reported for charge-parity violation in decays, using data collected in proton-proton collisions at recorded by the CMS experiment in 2018. The analysis uses a dedicated data set that corresponds to an integrated luminosity of 41.6 , which consists of about 10 billion events containing a pair of b hadrons, nearly all of which decay to charm hadrons.
View Article and Find Full Text PDFCureus
November 2024
Orthopaedic Surgery, University of Puerto Rico, Medical Sciences Campus, San Juan, USA.
Atypical fractures are diagnosed when an otherwise normal force causes a fracture in a patient using bisphosphonates chronically. These occur most commonly in the subtrochanteric region of the femur. Yet, the literature on atypical tibial shaft fractures is scarce.
View Article and Find Full Text PDFJ Addict Med
December 2024
From the Department of Family Medicine and Community Health, University of Massachusetts Chan Medical School, Worcester, MA (EP); University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico (BYPG); Baystate Health and University of Massachusetts Chan Medical School-Baystate, Springfield, MA (PDF), Department of Population and Quantitative Health Sciences, University of Massachusetts Chan Medical School, Worcester, MA (PDF); Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA (TJS); Institute for Health Equity and Social Justice Research, Northeastern University, Boston, MA (CS); and Department of Health Promotion and Policy, School of Public Health and Health Sciences, University of Massachusetts Amherst, Amherst, MA (EAE).
Objectives: As carceral settings increasingly offer medications for opioid use disorders (MOUD), community-based providers will need to navigate relationships with correctional agencies to ensure continuity of MOUD upon release. Although collaboration has been identified as critical between agencies, limited research is available that details how providers can work with jails. We describe the perspectives of MOUD providers about their experiences collaborating with jails that had recently begun to offer MOUD.
View Article and Find Full Text PDF