2 results match your criteria: "University of Prince Edward Island 550 University Ave[Affiliation]"
Enhanced Cryopreservation Efficacies of Ice Recrystallization Inhibiting Nanogels.
ACS Appl Mater Interfaces
October 2023
Department of Chemistry, University of Prince Edward Island 550 University Ave. Charlottetown, Prince Edward C1A 4P3, Canada.
Development of new cryopreservation technologies holds significant potential to revolutionize the fields of cell culture, tissue engineering, assisted reproduction, and transfusion medicine. The current gold standard small-cell permeating cryopreservation agents (CPAs) demonstrate promising cryopreservation efficacies but are cytotoxic and immunogenic at the concentrations required for cryopreservation applications. In comparison, new cell impermeable CPAs of nanodimensions demonstrate outstanding potential to overcome the drawbacks of existing CPAs.
View Article and Find Full Text PDFLow-dose neonatal domoic acid causes persistent changes in behavioural and molecular indicators of stress response in rats.
Behav Brain Res
May 2012
Department of Biomedical Sciences, University of Prince Edward Island 550 University Ave, Charlottetown, PE C1A4P3, Canada.
Article Synopsis
- Stress responses depend on a balanced nervous system that adapts to environmental changes; disruptions can lead to stress-related disorders.
- Research on rat pups treated with a low dose of domoic acid showed they developed seizure behaviors and structural brain changes resembling temporal lobe epilepsy when faced with stress later in life.
- The study found altered anxiety responses and cognitive flexibility in male rats, alongside specific changes in receptor expression linked to stress, indicating that early exposure to domoic acid affects stress response mechanisms and may help in studying the relationship between stress and neurological disorders.