Individual Acceleration-Speed Profile Variables: Comparison and Reliability Between Linear and Curvilinear Sprints.

Miras-Moreno, S, García-Ramos, A, Sašek, M, Cvjetičanin, O, Šarabon, N, Kavčič, I, and Smajla, D. Individual acceleration-speed profile variables: comparison and reliability between linear and curvilinear sprints. J Strength Cond Res XX(X): 000-000, 2024-The aim of this study was to compare linear sprint (LS) and curvilinear sprint (CS) to provide (a) the goodness-of-fit of individual acceleration-speed profile (ASP) and (b) the magnitude and within- and between-session reliability of the ASP variables (A0 [theoretical maximal acceleration], S0 [theoretical maximal velocity], and ASslope [slope of the linear ASP]).

Intensity of nursing work in a primary healthcare center: An observational study.

Objectives: In the sphere of occupational intensity, nursing stands recognized for its inherently demanding nature, marked by a rapid succession of tasks. Our primary aim was to assess the level of job intensity within nursing by analyzing the frequency and duration of activities performed by nurses, instances of task overlap, and the distribution of break times within a primary healthcare center.

Methods: This study was conducted using a descriptive working method.

Body Composition Trend in Slovene Adults: A Two-Year Follow-Up.

This research re-evaluates the prevalence of obesity in a cohort of 432 Slovenian adults two years after an initial population-based cross-sectional examination, utilizing the World Health Organization's body mass index (BMI) and total body fat percentage (FAT%) classifications. Herein, a medically approved electrical bioimpedance monitor was used to analyse body composition, and the results revealed a significant increase in the percentage of individuals classified as having overweight or obesity on the basis of BMI, from 40.7% initially to 45.

Dealing With the Complexity of Effective Population Size in Conservation Practice.

Effective population size () is one of the most important parameters in evolutionary biology, as it is linked to the long-term survival capability of species. Therefore, greatly interests conservation geneticists, but it is also very relevant to policymakers, managers, and conservation practitioners. Molecular methods to estimate rely on various assumptions, including no immigration, panmixia, random sampling, absence of spatial genetic structure, and/or mutation-drift equilibrium.

The interplay between hypothalamic and brainstem nuclei in homeostatic control of energy balance.

Energy balance and body weight are tightly regulated by homeostatic and hedonic systems of the brain. These systems are ultimately finely tuned by hypothalamic and extrahypothalamic neurocircuitry that modulate feeding and the appetite signalling cascade. The hypothalamus has been extensively researched and its role in homeostatic regulation of energy balance is well established.

Identification of Coumarin-Chalcone and Coumarin-Pyrazoline Derivatives as Novel Anti- Agents.

Introduction: Toxoplasmosis, a zoonotic infection caused by the apicomplexan parasite , affects a significant portion of the global human population. This condition, particularly dangerous for pregnant women and immunocompromised individuals, currently lacks effective treatment options.

Methods:  Eighteen coumarin-based derivatives were synthesized, comprising coumarin-chalcone hybrids (5a-i) and coumarin-pyrazoline hybrids (6a-i).

Acute Human Bocavirus 1 Infection in Children Hospitalized for Acute Bronchiolitis: A 2-Year Prospective Study.

Background: The objective of this prospective study was to assess the proportion and clinical consequences of human bocavirus 1 (HBoV1) replication in children hospitalized for acute bronchiolitis (AB) with HBoV1 DNA in the nasopharynx (NP).

Methods: For this purpose, we detected HBoV1 DNA and mRNA (evidence of viral replication and viable virus) in NP in cases and healthy control children. This research allowed us to distinguish active HBoV1 infections from inactive ones.

Effects of flywheel resistance training on countermovement jump performance and vastus lateralis muscle stiffness: A controlled study.

This study aimed to investigate the effects of an 8-week resistance training using flywheel (FW) device on countermovement jump (CMJ) performance and resting stiffness of the vastus lateralis (VL) muscle. Physically active adults were randomly assigned to a training intervention group (T;  = 18) and a control group (C;  = 13), which received no intervention. Jump performance variables and ultrasound-assessed resting VL shear modulus were measured before and after the intervention.

Bioarchaeological Perspectives on Late Antiquity in Dalmatia: Paleogenetic, Dietary, and Population Studies of the Hvar - Radošević burial site.

Late Antiquity Dalmatia was a time and place of political unrest in the Roman Empire that influenced the lives of those in that region. The Late Antique burial site of Hvar - Radošević, spanning the 3 to 5 centuries CE, is located on the Croatian Dalmatian island of Hvar. Given the time frame and location on a busy marine trade route, the study of this burial site offers us a glimpse into the lives of the Late Antique population living on this island.

Infantis Adhesion to Various Surfaces and In Vitro Antimicrobial Efficacy of Commercial Disinfectants.

Infantis poses a significant challenge in poultry production due to its persistence and resistance to disinfectants. This study investigated the survival of the Infantis strain on different surfaces and evaluated the efficacy of disinfectants in both preventing and treating biofilms. The survival of the tested Infantis strain was assessed on plastic and stainless steel surfaces after 24 and 48 h.

Computational Analysis of S1PR1 SNPs Reveals Drug Binding Modes Relevant to Multiple Sclerosis Treatment.

Multiple sclerosis (MS) is an autoimmune disorder of the central nervous system (CNS) characterized by myelin and axonal damage with a globally rising incidence. While there is no known cure for MS, various disease-modifying treatments (DMTs) exist, including those targeting Sphingosine-1-Phosphate Receptors (S1PRs), which play important roles in immune response, CNS function, and cardiovascular regulation. This study focuses on understanding how nonsynonymous single nucleotide polymorphisms (rs1299231517, rs1323297044, rs1223284736, rs1202284551, rs1209378712, rs201200746, and rs1461490142) in the S1PR1's active site affect the binding of endogenous ligands, as well as different drugs used in MS management.

The Influence of COVID-19 on Antimicrobial Resistance Trends at a Secondary Care Hospital in Slovenia: An Interrupted Time Series Analysis.

Our study aimed to determine the development of antibiotic resistance during the peri-pandemic period in a regional secondary care hospital using an interrupted time series analysis. . We analyzed data from seven years, accounting for 441,149 patient days.

Assessment of Functioning and the Integration of Patients After Traumatic Brain Injury in Their Homes and Social Environments Following Inpatient Rehabilitation.

Introduction: Patients with head injuries usually return to their home environments after completing rehabilitation, which is an additional challenge in the case of functional, motor or cognitive impairment. In order to identify the problems that such patients face and to objectify their problems with integration, we used the Community Integration Questionnaire-Revised (CIQ-R). At the same time, the validity of the translation of the questionnaire into Slovenian was checked.

Attitudes toward Medically Assisted Dying Among the General Public in Slovenia.

The aim of this study was to explore public attitudes toward medically assisted dying, focusing on the role of socio-demographic factors, mental health conditions, and personal experiences. Data were collected via an online panel in Slovenia, which consisted of 567 participants (53.1% men) aged 18 years and older.

The relationship between climate classes and particulate matters over Europe.

Present and future Köppen-Geiger climate maps and time series of particulate matter (PM10) at continental scale were used to investigate the relationship between spatial patterns of PM10 and climate zones. Five main patterns (spatial clusters) of PM10 were found over the European continent, which show a good spatial overlap with the main Köppen-Geiger climate zones. The map of future climate, which shows a poleward movement of the warmer climate zones, an expansion of the (semi-)arid zones and a shrinking of the polar and tundra zones, indicates a higher PM10 concentration, especially in the northern part of Europe.

Understanding health and illness among incarcerated persons in the Slovenian correctional system: A qualitative study.

Understanding the perspectives of incarcerated persons on health and illness, as well as the social contexts influencing these perspectives, is important for developing healthcare interventions that effectively address their specific needs and improve overall well-being. The aim of this study was to explore and understand the complex, multi-dimensional experiences of health and illness among incarcerated persons within the Slovenian correctional system. This study employed an interpretative descriptive design.

Analytical Determination of Squalene in Extra Virgin Olive Oil and Olive Processing By-Products, and Its Valorization as an Ingredient in Functional Food-A Critical Review.

Squalene is a bioactive compound with significant health benefits, predominantly found in extra virgin olive oil (EVOO) and its processing by-products. This critical review explores the analytical determination of squalene in EVOO and various by-products from olive oil production, highlighting its potential as a valuable ingredient in functional foods. An overview of existing analytical methods is provided, focusing on different approaches to sample preparation before analytical determination, evaluating their effectiveness in quantifying squalene concentrations.

Edible Insects: Consumption, Perceptions, Culture and Tradition Among Adult Citizens from 14 Countries.

Although edible insects (EIs) are encouraged as a sustainable source of protein, their consumption is not as generalised as other types of food that are internationally accepted. While in some regions of the world, EIs are part of the gastronomic and cultural traditions, in other regions, people are not so receptive to this type of food, and some people even express some disgust towards it. Hence, this research focused on the habits of the participants regarding the consumption of insects as well as their perceptions about EIs being or not a part of the local culture or gastronomic patrimony.

The workshops on computational applications in secondary metabolite discovery (CAiSMD).

We report the outcomes of the second session of the free online open-access workshop "Computational Applications in Secondary Metabolite Discovery (CAiSMD) 2022" that took place from 09 to 11 March 2022. The first session was held from 08 to 10 March 2021 and drew the attention of many early career scientists from academia and industry. The 23 invited speakers of this year's workshop also came from academia and industry and 222 registered participants from five continents (Africa, Asia, Europe, South, and North America) took part in the workshop.

Linear and Volumetric Polyethylene Wear Patterns after Primary Cruciate-Retaining Total Knee Arthroplasty Failure: An Analysis Using Optical Scanning and Computer-Aided Design Models.

(1) Background: Analyses of retrieved inserts allow for a better understanding of TKA failure mechanisms and the detection of factors that cause increased wear. The purpose of this implant retrieval study was to identify whether insert volumetric wear significantly differs among groups of common causes of total knee arthroplasty failure, whether there is a characteristic wear distribution pattern for a common cause of failure, and whether nominal insert size and component size ratio (femur-to-insert) influence linear and volumetric wear rates. (2) Methods: We digitally reconstructed 59 retrieved single-model cruciate-retaining inserts and computed their articular load-bearing surface wear utilizing an optical scanner and computer-aided design models as references.

Protective Capacity of Infusion Against Intestinal Barrier Disruption and Translocation of Infantis.

Background: is a Mediterranean plant with well-known anti-inflammatory activity, but our previous whole transcriptome analysis has found that infusion (HII) can also affect cytoskeletal rearrangement and tight junctions. The goal of the present study was to determine if HII improves the intestinal barrier (IB) dysfunction and by what mechanism.

Methods: Caco-2 cells on Transwell inserts were used as a model of IB permeability.

Backcrossing Failure between Sikitita Olive and Its Male Parent Arbequina: Implications for the Self-Incompatibility System and Pollination Designs of Olive Orchards.

Backcrossing between Sikitita and its male parent Arbequina, offers the possibility to check the suitability of different self-incompatibility models proposed for olive. To determine Sikitita's response to self- and cross-pollination treatments, including pollination with its father Arbequina, we compared the parameters following pollen-pistil interaction, the resulting initial and final fruit set, and the paternity of the seeds produced under different crosses. The results showed that Sikitita behaves as a self-incompatible cultivar due to the inhibition of pollen tube growth in the pistil of self-pollinated flowers.