A pioneering longterm experiment on mesophotic macrofouling communities in the North Atlantic.

The mesophotic zone represents one of our planet's largest and least explored biomes. An increasing number of studies evidence the importance of macrofouling species in marine ecosystems, but information on these communities and the factors influencing their structures at mesophotic depths remain poor. This lack of understanding limits our ability to predict anthropogenic impacts or conduct restoration operations in the mesophotic and the lower boundary of the euphotic zones.

Impact of trace elements (total and labile fraction) on the anaerobic digestion activity and microbial community structure.

Trace elements (TEs) in anaerobic digestion (AD) are known to be essential for optimal biogas production, but inhibitive in excessive concentrations. However, the mechanisms of inhibition are not fully understood. The effects of the addition essential TEs (Co, Cu and Ni) and a non-essential TE (Cd) on the microbial community structure of AD were studied in lab-scale reactors, using total TE concentrations that ranged from 0 to 100 μM.

Preclinical studies on the antitumor and non-toxic effect of combining pirfenidone with vinorelbine and carboplatin in non-small cell lung cancer.

Non-small cell lung cancer (NSCLC) shows limited therapeutic response to vinorelbine and carboplatin. Combining these drugs with an antifibrotic drug may enhance their antitumor effect. Pirfenidone is an antifibrotic drug whose antitumor activity has been described in different types of cancer.

Operative Treatment of Nonprimary Osteochondral Lesions of the Talus: A Systematic Review.

Background: Nonprimary osteochondral lesions of the talus (OLT) pose a significant challenge in orthopaedics, with no definitive consensus on optimal surgical treatment.

Purpose: To consolidate the most recent evidence on operative treatments for nonprimary OLT by assessing patient-reported outcomes (PROs), postoperative complications, and clinical failures.

Study Design: Systematic review; Level of evidence, 4.

Synovial chondromatosis, a cause of hip pain: a case report.

Background: Synovial chondromatosis is a proliferative disease of the synovium associated with cartilage metaplasia that causes localized joint pain and affects its function.

Case Presentation: A 63-year-old white woman presented with right hip pain, lasting over 10 years. Pelvic radiography showed right hip osteoarthritis and ipsilateral periacetabular opacities.

Using artificial intelligence to prioritize pathology samples: report of a test drive.

The digital transformation of pathology, through automation and computational tools, addresses current challenges in the field. This study evaluates Paige Pan Cancer, a novel artificial intelligence tool based on the Virchow foundation model, designed to flag invasive cancer in haematoxylin and eosin-stained slides from 16 primary tissue types. Using 62 cases from the Ipatimup Pathology Laboratory, we found the tool had a sensitivity of 93.

Are endurance runners at higher risk of depression? Screening for depression and risk factors.

Depression is an important public health issue. In the general adult population, about 6.7% are affected.

CNN-Based Device-Agnostic Feature Extraction From ONH OCT Scans.

Purpose: Optical coherence tomography (OCT)-derived measurements of the optic nerve head (ONH) from different devices are not interchangeable. This poses challenges to patient follow-up and collaborative studies. Here, we present a device-agnostic method for the extraction of OCT biomarkers using artificial intelligence.

Organization of angiology in countries with associate societies of International Union of Angiology.

Angiology is a multidisciplinary medical discipline, consequently in some countries multidisciplinary vascular centres were organized, which provide comprehensive management of patients with different vascular diseases. However, the organization of the care for vascular patients differs between the countries. Therefore, we aimed to check the organization of angiology (vascular surgery and vascular medicine) in countries-associate members of IUA and to stimulate the development of multidisciplinary vascular centres.

Mini-skin longitudinal incision versus traditional longitudinal incision for carotid endarterectomy in patients with carotid artery stenosis: a systematic review and meta-analysis.

Introduction: Carotid endarterectomy (CEA) remains the gold standard intervention for stroke prevention in patients with carotid artery stenosis but the surgical technique continues evolving with research being conducted on minimally invasive alternatives. Mini-skin incision CEA has emerged as a more aesthetically appealing and less painful alternative to the traditional technique with a potential impact on main procedural events. We aimed to provide a review of the literature and to compare the mini-skin incision with the traditional approach.

Protocol: Complementarity between informal care and formal care to adults: Knowledge mapping through a scoping review of the literature.

This is the protocol for a Campbell systematic review. The aim of this scoping review is to map, describe and characterize the available evidence on the role that formal care might have in complementing informal caregivers role - romantic partners, parallel family members (e.g.

Fat extraction methodology can affect the food fatty acid profile: Improvement of a protocol more environmentally friendly.

Fatty acids (FAs) are biochemical components of food, essential for human health due to their numerous biological functions. However, many of then if consumed in excess can trigger disfunctions/illness. Therefore, analytical methods, such as gas chromatography (GC-FID) are essential for the accurate identification and quantification of FAs, playing an important role in food safety and quality assessment.

African bat database: curated data of occurrences, distributions and conservation metrics for sub-Saharan bats.

Accurate knowledge of species distributions is foundational for effective conservation efforts. Bats are a diverse group of mammals, with important roles in ecosystem functioning. However, our understanding of bats and their ecological importance is hindered by poorly defined ranges, mostly as a result of under-recording.

The effect of instructed refreshing on working memory: Is the memory boost a function of refreshing frequency or refreshing duration?

Refreshing is assumed to reactivate the contents of working memory in an attention-based way, resulting in a boost of the attended representations and hence improving their subsequent memory. Here, we examined whether the refreshing-induced memory boost is a constant or a gradual, time-dependent phenomenon. If the beneficial effect of refreshing on memory performance is due to the information being selected for refreshing (i.

Optical immunosensor panel using quantum dot-antibody conjugates for highly sensitive detection of carbohydrate antigen 19-9 (CA19-9).

This study introduces a fluorescent immunosensor colour panel with antibody-conjugated quantum dots for detecting CA19-9 in human serum. The immunosensors presented decreasing fluorescence with increasing CA19-9 concentrations, with a linear detection range from 0.01 to 501.

Development and validation of a multicompound LLE-LC-MS/MS method for biomonitoring of hazardous medicinal products in urine of exposed workers.

Antineoplastic drugs are carcinogens, mutagens, or teratogenic substances, which can pose serious risks to professionals. Concerns about chronic exposure to these hazardous medicinal products (HMPs) have led to their prominence in the EU strategic framework on health and safety at work 2021-2027. To estimate and mitigate human exposure to HMPs, regular monitoring programs and, consequently, reliable, sensitive, multicomponent methods are crucial.

Geogenic characterisation of airborne particles from the former Regoufe mining area.

Mining operations contribute to higher environmental contaminant levels, such as particulate matter (PM) hosting potentially toxic elements (PTE). This study aimed to comprehensively characterise atmospheric PM in an environment impacted by former tungsten-tin mining exploration at Regoufe mine (Arouca, Portugal). Although this is a deactivated mine, its location near population clusters and integration into a Geopark belonging to the "World Geoparks Network" with frequent presence of hikers highlight the importance of air quality monitoring to keep its Geopark classification.

A structural equation model of emotion knowledge and verbal intelligence in peer acceptance in a sample of Portuguese preschoolers.

Using a mediation model, this study examined the role of verbal intelligence and emotion knowledge in peer acceptance in a sample of Portuguese preschool children. Participants were 444 5-year-olds (214 girls and 230 boys). Emotion knowledge was assessed with the Portuguese version of the Assessment of Children's Emotion Skills.