2 results match your criteria: "University of Pitttsburgh School of Medicine[Affiliation]"
CMV-IVIG for prevention of Epstein Barr virus disease and posttransplant lymphoproliferative disease in pediatric liver transplant recipients.
Am J Transplant
August 2006
Department of Pediatrics, University of Pitttsburgh School of Medicine, Pennsylvania, USA.
A randomized controlled trial of CMV-IVIG (cytomegalovirus-intravenous immunoglobulin) for prevention of Epstein Barr virus (EBV) posttransplant lymphoproliferative disease (PTLD) in pediatric liver transplantation (PLTx) recipients was begun in Pittsburgh and subsequently expanded to four additional sites. Protocol EB viral loads were obtained in a blinded fashion; additional loads could be obtained for clinical indications. Patients were followed for 2 years post-LTx.
View Article and Find Full Text PDFVariability in cerebral oxygen delivery is reduced in premature neonates exposed to chorioamnionitis.
Pediatr Res
February 2006
Department of Pediatrics, University of Pitttsburgh School of Medicine, PA 15217, USA.
Article Synopsis
- Premature infants who are exposed to chorioamnionitis have a higher chance of developing brain issues like periventricular leukomalacia (PVL) and intraventricular hemorrhage (IVH), which may be linked to inflammation and blood flow changes in the brain.
- A study involving 49 infants showed that those exposed to chorioamnionitis had lower intermediate variability in measures of their cerebral oxygen delivery, particularly on the first day of life, which suggests a potential connection to brain injury risk.
- The research highlights the need for further investigations to understand how these changes in cerebral oxygen delivery relate to blood flow regulation and oxygen use in premature infants.