Separating a multicomponent and multiphase liquid mixture with a 3D-printed membrane device.

The separation of multicomponent and multiphase liquid mixtures is critical in many important applications, , wastewater treatment. While conventional technologies have been utilized in the separation, it usually takes many steps, resulting in high cost and energy consumption. Here we have demonstrated that, using a 3D-printed membrane device with multiple selectivity, a multicomponent and multiphase liquid mixture can be separated in a much more efficient way.

Delivery of a cyclic adenosine 3',5'-monophosphate response element-binding protein (creb) mutant to seminiferous tubules results in impaired spermatogenesis.

FSH binding to Sertoli cells is required for optimal production of sperm in mammals. The cAMP response element-binding protein (CREB) is a major mediator of FSH-induced changes in gene expression. To determine whether CREB is required for spermatogenesis, an adenovirus encoding a phosphorylation-defective CREB mutant (AdCREBm1) was used to inhibit CREB activity in Sertoli cells.