2,405 results match your criteria: "University of Picardy Jules Verne; Institut Faire Faces. Electronic address: testelin.sylvie@chu-amiens.fr.[Affiliation]"

Background: The impact of cirrhosis on the postoperative outcomes of distal pancreatectomy is yet to be reported. We aimed to evaluate the outcomes of distal pancreatectomy in patients with cirrhosis.

Methods: We conducted a retrospective, multicentric study patients with cirrhosis who underwent planned distal pancreatectomy between 2008 and 2020 in French high volume centers.

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Negative central activity in extremely preterm newborns: EEG characterization and relationship with brain injuries and neurodevelopmental outcome.

Clin Neurophysiol

July 2024

INSERM UMR 1105, Research Group on Multimodal Analysis of Brain Function, University of Picardie Jules Verne, rue René Laennec, 80054 Amiens Cedex, France; Pediatric Neurophysiology Unit, Amiens-Picardie University Hospital, 1 rue du Professeur Christian Cabrol, 80054 Amiens Cedex, France.

Objective: To characterize Negative Central Activity (NCA), an overlooked electroencephalographic activity of preterm newborns and investigate its relationship with brain injuries, dysfunction, and neurodevelopmental outcome.

Methods: 109 preterm infants (23-28 weeks) were retrospectively included. NCA were selected at the negative peak on EEG.

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Manganese addition effect on structural and physical properties of calcium borovanadate glasses.

Heliyon

May 2024

Laboratoire de Chimie Appliquée des Matériaux, Centre des Sciences des Matériaux, Faculty of Science, Mohammed V University in Rabat, Avenue Ibn Battouta, BP, 1014, Rabat, Morocco.

New calcium borovanadate glass containing manganese ions within the system x MnO-(30-x) VO-50 BO-20 CaO has been elaborated in this work using melt quench process. The primary objective of this research is to examine the influence of introducing MnO upon the various properties of the elaborated glass specimens including physical, thermal, structural, optical and magnetic properties. X-ray diffraction indicated that the samples prepared were amorphous.

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Introduction: This research explores the impact of the COVID-19 pandemic on psychotherapists' practices and their ability to maintain a framework despite a shared reality with their patients. The specific focus in this article is on the Lebanese context, which is characterized by a series of crises including economic collapse, the COVID-19 pandemic, and the Beirut blast. The objective of this study was to examine how the destabilization of the meta-frame due to crises necessitates adaptations in theoretical knowledge, practice, and setting.

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European validation of the classification for the anticipated difficulty of liver transplantation.

HPB (Oxford)

August 2024

Department of Digestive, Hepato-Biliary and Pancreatic Surgery and Liver Transplantation, AP-HP Pitié-Salpêtrière Hospital, Paris, France; Sorbonne Université, Paris, France; Centre de Recherche de Saint-Antoine (CRSA), INSERM, UMRS-938, Paris, France. Electronic address:

Background: Appropriate risk stratification for the difficulty of liver transplantation (LT) is essential to guide the selection and acceptance of grafts and avoid morbidity and mortality.

Methods: Based on 987 LTs collected from 5 centers, perioperative outcomes were analyzed across the 3 difficulty levels. Each LT was retrospectively scored from 0 to 10.

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Acute myocarditis: An urgent need for evidence-based recommendations.

Arch Cardiovasc Dis

June 2024

MIRACL.ai laboratory (Multimodality Imaging for Research and Analysis Core Laboratory and Artificial Intelligence), University Hospital of Lariboisière, AP-HP, 75010 Paris, France; Department of Cardiology, University Hospital of Lariboisière, AP-HP, Université Paris Cité, 75010 Paris, France; MASCOT-UMRS 942, Inserm, University Hospital of Lariboisière, AP-HP, 75010 Paris, France.

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Article Synopsis
  • Minimally invasive surgery (MIS) for left pancreatic resections has been increasingly utilized, but its advantages over traditional open surgery for distal pancreatectomy in treating pancreatic neuroendocrine tumors are still debated.
  • A retrospective study involving 274 patients across 21 French centers analyzed short and long-term outcomes of MIS versus open surgery, focusing on factors like tumor size and patient characteristics.
  • Results showed that MIS reduced major complications and delayed gastric emptying while maintaining comparable survival rates, suggesting it is a safe option for patients with resectable left pancreatic neuroendocrine tumors.
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KCNJ5 mutations in familial and non-familial primary aldosteronism.

Eur J Endocrinol

June 2024

Department of Endocrinology-Diabetes Mellitus and Nutrition, Amiens University Hospital, 80054 Amiens, France.

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Introduction: Bio stimulants are substances and/or microorganisms that are used to improve plant growth and crop yields by modulating physiological processes and metabolism of plants. While research has primarily focused on the broad effects of bio stimulants in crops, understanding their cellular and molecular influences in plants, using metabolomic analysis, could elucidate their effectiveness and offer possibilities for fine-tuning their application. One such bio stimulant containing galacturonic acid as elicitor is used in agriculture to improve wheat vigor and strengthen resistance to lodging.

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Article Synopsis
  • * It found that patients with mild residual TR had an 85% survival rate, while those with moderate and severe TR had significantly lower rates of 70% and 44%, respectively.
  • * The research emphasizes the need for a more detailed classification of TR severity to better predict patient outcomes and highlights the goal of achieving at least mild to moderate residual TR for successful interventions.
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Background And Aims: Presentation, outcome, and management of females with degenerative mitral regurgitation (DMR) are undefined. We analysed sex-specific baseline clinical and echocardiographic characteristics at referral for DMR due to flail leaflets and subsequent management and outcomes.

Methods: In the Mitral Regurgitation International Database (MIDA) international registry, females were compared with males regarding presentation at referral, management, and outcome (survival/heart failure), under medical treatment, post-operatively, and encompassing all follow-up.

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Background: Both vedolizumab and ustekinumab can be considered for the treatment of ulcerative colitis [UC], but head-to-head trials are lacking.

Aim: We aimed to compare the effectiveness of vedolizumab and ustekinumab after anti-tumour necrosis factor [anti-TNF] failure in UC patients.

Patients And Methods: In this multicentre study, we included consecutive adult patients with UC, with partial Mayo score >2 and prior anti-TNF exposure, treated with vedolizumab or ustekinumab between January 2019 and August 2022.

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Cognitive decline, mental health and mindset factors can all affect the autonomy and well-being of older adults. As the number of older adults across the globe increases, interventions to improve well-being are urgently needed. Improvisational theatre (improv) and improv-based interventions are well-suited to address this need.

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Metabolic and neurobehavioral disturbances induced by purine recycling deficiency in .

Elife

May 2024

Genes Circuits Rhythms and Neuropathology, Brain Plasticity Unit, CNRS, ESPCI Paris, PSL Research University, Paris, France.

Article Synopsis
  • Adenine phosphoribosyltransferase (APRT) and hypoxanthine-guanine phosphoribosyltransferase (HGPRT) are key enzymes in purine recycling, and mutations in HGPRT lead to Lesch-Nyhan disease (LND), which currently has no treatment.
  • The fruit fly model was used to study LND mechanisms, revealing that lack of HGPRT activity leads to various metabolic and behavioral issues in flies, including increased uric acid levels and locomotor problems.
  • Feeding adenosine during development showed promise in rescuing seizure-like behavior, and the study suggests that the fruit fly could help in understanding LND better, potentially leading to therapeutic approaches.
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Background: Bilingualism's impact on cognitive assessment remains underexplored. This study analyzes the efficacy of the Mini-Mental State Examination (MMSE) as a screening tool for bilinguals, specifically examining the influence of language choice on balanced and unbalanced Lebanese bilinguals (Arabic-French) and its implications for diagnosing cognitive impairment.

Methods: Ninety-three bilingual healthy controls (mean age = 67.

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Structural and biochemical characterization of SmoPG1, an exo-polygalacturonase from Selaginella moellendorffii.

Int J Biol Macromol

June 2024

UMRT INRAE 1158 BioEcoAgro - Biologie des Plantes et Innovation, Université de Picardie Jules Verne, UFR des Sciences, 33 Rue St Leu, 80039 Amiens, France. Electronic address:

Polygalacturonases (PGs) can modulate chemistry and mechanical properties of the plant cell wall through the degradation of pectins, one of its major constituents. PGs are largely used in food, beverage, textile, and paper industries to increase processes' performances. To improve the use of PGs, knowledge of their biochemical, structural and functional features is of prime importance.

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Article Synopsis
  • The advancement in neuroscientific research has improved our understanding of sex differences in the human brain, extending beyond just the hypothalamus to the entire brain's structures and functions.
  • There is, however, a lack of knowledge regarding these differences in neonates and infants, which could be important for understanding early-developing sex-linked diseases.
  • This review summarizes existing research on the morphological, structural, and network-level sex differences in the brains of young children and touches upon the sex bias in certain brain disorders that impact them.
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Background And Purpose: Extreme hypofractionated stereotactic body radiotherapy (SBRT) is a therapeutic alternative for localized low- or intermediate-risk prostate cancer. Despite the availability of several studies, the toxicity profile of SBRT has not been comprehensively described. This real-world evidence study assessed the efficacy and toxicities associated with this regimen, and potential prognosis factors for genitourinary toxicities.

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Cancer patients are at a high risk of complications in cases of infection, and head and neck cancers (HNC) are no exception. Since late 2019, SARS-CoV-2 has caused a global health crisis, with high rates and severe forms of the disease in cancer patients. Hospitalization, surgery and radiotherapy were rapidly described as increasing the risk of infection.

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On the Lanthanide Effect on Functional Properties of 0.94NaBiTiO-0.06BaTiO Ceramic.

Materials (Basel)

April 2024

Laboratory of Physics of Condensed Matter (LPMC), University of Picardie Jules Verne, Scientific, Pole, 33 rue Saint-Leu, 80039 Amiens, France.

The beneficial effects of lanthanide incorporation into 0.94NaBiTiO-0.06BaTiO (BNT-BT) matrix on its functional properties were investigated.

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Background/objectives: In the absence of an effective antiviral treatment for BK polyomavirus (BKPyV), a better understanding of the epidemiology and time course of BKPyV replication after kidney transplantation is needed to limit the virus's impact on the graft outcome.

Methods: In a 7-year study, we screened more than 430 kidney transplant recipients and analyzed the time course and virological characteristics of BKPyV replication.

Results: Urinary viral replication was observed in 116 (27%) of the 430 patients, and 90 of the 116 (78%) had viral DNAemia.

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Background: Major advances have been made in reconstructive surgery in the last decades to reduce morbidity in head and neck cancer. Flaps are now present in 80% of patients with oral cavity cancer to cover anatomic, functional, and cosmetic needs. However, gaps in interdisciplinary innovation transfer from surgery to postoperative radiotherapy (poRT) remain challenging.

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Polypharmacy in Patients with CKD: A Systematic Review and Meta-Analysis.

Kidney360

June 2024

Department of Nephrology and Hypertension, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.

Key Points: The prevalence of polypharmacy in patients with CKD was over 80%. Polypharmacy was highest in patients with a kidney transplant and those receiving dialysis. Polypharmacy is associated with worse clinical outcomes, lower quality of life, and medication-related problems in patients with CKD.

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Severe asthma care trajectories: the French RAMSES cohort.

ERJ Open Res

March 2024

Department of Respiratory Diseases, Reference Center for Rare Pulmonary Diseases, Bichat Hospital, AP-HP, Paris, France.

Article Synopsis
  • - The French RAMSES study compared severe asthma patients managed in tertiary referral centres (TRCs) versus secondary care centres (SCCs) to understand differences in patient characteristics and care practices.
  • - A total of 2046 patients were included: 73.4% from TRCs and 26.6% from SCCs; key findings showed that TRC patients had more comorbidities but lower blood eosinophil counts and benefited more from educational programs and in-depth investigations.
  • - The study concluded that asthma care trajectories and patient phenotypes varied significantly between TRCs and SCCs, emphasizing the need for standardized approaches to managing severe asthma.
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