2,405 results match your criteria: "University of Picardy Jules Verne; Institut Faire Faces. Electronic address: testelin.sylvie@chu-amiens.fr.[Affiliation]"

We report on single-phase NaV(PO) compositions (1.5 ≤ x ≤ 2.5) of the Na super ionic conductor type, obtained from a straightforward synthesis route.

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  • The study investigates the presence of human papillomavirus (HPV) in the semen of men seeking infertility treatment at Amiens University Hospital from May to October 2021, involving 461 participants who provided informed consent.
  • Semen samples were analyzed for HPV using PCR, revealing that 22.3% of men carried HPV, with high-oncogenic-risk types being the most common (57.6%).
  • The analysis found significant associations between HPV carriage and factors like abnormal sperm quality, type of infertility, presence of varicocele, and certain testicular conditions, indicating that HPV may contribute to infertility risks.
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Individuals with neurodevelopmental disorders (NDDs) are more susceptible to developing severe or resistant mood disorders. However, they often face challenges in accessing specific treatments. To understand the barriers to treatment in this group, we conducted a secondary analysis of a multicenter observational study on 305 adolescents referred to specialized care (mean age 14.

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Attention Deficit Hyperactivity Disorder (ADHD) is characterized by deficits in attention, hyperactivity, and/or impulsivity. Resting-state functional connectivity analysis has emerged as a promising approach for ADHD classification using resting-state functional magnetic resonance imaging (rs-fMRI), although with limited accuracy. Recent studies have highlighted dynamic changes in functional connectivity patterns among ADHD children.

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Biological nitrogen fixation is a fundamental part of ecosystem functioning. Anthropogenic nitrogen deposition and climate change may, however, limit the competitive advantage of nitrogen-fixing plants, leading to reduced relative diversity of nitrogen-fixing plants. Yet, assessments of changes of nitrogen-fixing plant long-term community diversity are rare.

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  • Acute kidney injury (AKI) can progress to acute kidney disease (AKD) and potentially to chronic kidney disease (CKD), creating significant health risks, including cardiovascular complications.
  • In a mouse study, researchers found that kidney injury resulted in early heart and blood vessel dysfunction, marked by specific changes in protein expression and increased levels of harmful toxins over time.
  • The findings emphasize the importance of understanding the early effects of AKD on cardiovascular health to find ways to prevent future heart issues.
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Background: The anti-neutrophil cytoplasmic antibody (ANCA) renal risk score (ARRS) for predicting renal survival in ANCA-associated vasculitis (AAV) had not previously been validated in adults over 65 years of age and presenting impairments associated with an aging kidney, a high cardiovascular comorbidity burden and prevalent microscopic polyangiitis.

Methods: We retrospectively studied a cohort of 192 patients over 65 years of age [median (interquartile range) age: 73 (68-78) years], including 17.2% with renal-limited vasculitis, 49.

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  • A study conducted in France during the 2023-24 RSV season analyzed the effectiveness of nirsevimab, a monoclonal antibody, in preventing RSV infections in infants, focusing on breakthrough cases.
  • Out of 695 RSV-infected infants, researchers sequenced the full-length RSV genome of 545 infants, identifying that 48% had breakthrough infections despite receiving nirsevimab.
  • While no resistance was found in RSV-A infections from nirsevimab-treated infants, two cases of RSV-B showed substitutions linked to resistance, indicating a potential concern for the antibody's effectiveness against this variant.
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Physicochemical, Rheology, and Mid-Infrared Spectroscopy Techniques for the Characterization of Artisanal and Industrial Maroilles Cheeses.

Foods

September 2024

University Artois, University Lille, University Littoral Côte d'Opale, University Picardie Jules Verne, University Liège, INRAE, Junia, UMR-T 1158, BioEcoAgro, F-62300 Lens, France.

The investigation of the central and external zones of ten industrial and artisanal Maroilles cheeses showed differences in their physicochemical parameters, namely fat, pH, moisture content, ash, and color. This difference significantly impacted the rheological properties of the investigated cheeses, which depended on the protein network englobing lipid and water and its interaction with the other components. Overall, Maroilles cheeses had an elastic-like behavior, with the central zones exhibiting the greatest viscoelastic modules (G' and G″).

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  • * Results indicated that post-COVID-19 athletes had higher lean mass and better lung capacity, but similar heart rate variability and blood pressure compared to controls.
  • * Overall, elite athletes showed resilience in cardiovascular health after COVID-19, yet the study underscores the need for ongoing monitoring of their cardiovascular function.
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Autonomous nervous system responses to environmental-level exposure to 5G's first deployed band (3.5 GHz) in healthy human volunteers.

Exp Physiol

December 2024

Department of Experimental Toxicology and Modeling (TEAM), Institut National de l'Environnement Industriel et des Risques (INERIS), Verneuil-en-Halatte, France.

Following the global progressive deployment of 5G networks, considerable attention has focused on assessing their potential impact on human health. This study aims to investigate autonomous nervous system changes by exploring skin temperature and electrodermal activity (EDA) among 44 healthy young individuals of both sexes during and after exposure to 3.5 GHz antenna-emitted signals, with an electrical field intensity ranging from 1 to 2 V/m.

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Cerebral air embolism following a hemodialysis session successfully treated with hyperbaric oxygen: a case report.

Ther Adv Neurol Disord

October 2024

Department of Nephrology, Dialysis, and Transplantation, Amiens University Hospital, University of Picardie Jules Verne, F-80054 Amiens, France.

Article Synopsis
  • A 39-year-old woman developed cerebral air embolism (CAE) during hemodialysis due to a faulty central venous catheter, which can be a rare but serious complication, especially affecting the brain.
  • She initially presented with a seizure and was monitored in the Intensive Care Unit, later experiencing worsening symptoms such as aphasia and hemiplegia before being treated with hyperbaric oxygen therapy (HBOT).
  • After three sessions of HBOT, she fully recovered, with post-treatment seizures linked to hyperoxia, underscoring the need for vigilant monitoring and immediate treatment in lung transplant patients undergoing hemodialysis.
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Background: In prior randomised controlled trials, lung cancer screening using low-dose computed tomography (LDCT) has been shown to reduce lung cancer mortality and overall mortality. Despite these results, organised screening in France remains a challenge. This study assessed the feasibility and efficacy of lung cancer screening within a real-life context in a French administrative territory.

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Use of free preventive dental programme for children: 10 years of Lov'U'r Teeth, France.

J Paediatr Child Health

December 2024

National Institute for Health and Medical Research (INSERM), CESP Unit 1018, Prevention and Primary Care Team, Paul Brousse Hospital, Villejuif, France.

Article Synopsis
  • Lov'U'r Teeth is a French dental health program aimed at children aged 6 to 15, offering free preventive dental care and individual advice, but it was previously under-utilized.
  • A study analyzing data from over 26,000 children found that participation increased by 4.2 percentage points from 2009 to 2019, with the highest participation at age 6 and significant barriers for children from low-income households.
  • Despite some improvement, the program still reflects social inequalities, as poorer children are less likely to participate, indicating a need for better outreach and communication about the program's benefits.
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Introduction: There are no published data on the written language skills of gifted children (GC). The objective of the present study was to evaluate reading abilities of GC vs. normative data from typically developing French children (TDC).

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  • Climate change often leads to habitat shifts for species towards the poles, but other factors also play a significant role in determining species distribution.
  • A study on European forest plants shows that they are more likely to shift westward rather than northward, with westward movements being 2.6 times more common.
  • These shifts are primarily driven by nitrogen deposition and recovery from past pollution, indicating that biodiversity changes are influenced by multiple environmental factors, not just climate change alone.
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  • The study focuses on improving the distinction between brain metastasis progression (BMP) and brain radionecrosis (BRN) using advanced F-FDOPA PET/CT technology.
  • A new method involves a quick 3-second sampling during a 4-minute acquisition, applied to 15 patients with 19 metastases, to analyze activity ratios in brain lesions.
  • Results showed the VOImax/CLmean ratio had high diagnostic accuracy (94.7%) and successfully differentiated BMP from BRN, suggesting the new approach is more efficient than traditional methods.
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Defining mucosal healing in randomized controlled trials of inflammatory bowel disease: A systematic review and future perspective.

United European Gastroenterol J

November 2024

Department of Gastroenterology, INFINY Institute, FHU-CURE, Nancy University Hospital, and INSERM, Nutrition-Genetics and Environmental Risk Exposure, University of Lorraine, Vandœuvre-lès-Nancy, France.

Background: Mucosal healing (MH) is an established treatment goal in inflammatory bowel disease (IBD). However, various definitions of MH exist. We aimed to identify how MH is defined in randomized controlled trials (RCTs) in ulcerative colitis (UC) and Crohn's disease (CD).

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The treatment of Mycobacterium avium infections is still long, complex, and often poorly tolerated, besides emergence of resistances. New active molecules that are more effective and better tolerated are deeply needed. Mefloquine and its enantiomers ((+) Erythro-mefloquine ((+)-EMQ) and (-)-Erythro-mefloquine ((-)-EMQ)) have shown efficacy in both in vitro and in vivo, in a mouse model of M.

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Enzymatically cross-linkable sulfated bacterial polyglucuronic acid as an affinity-based carrier of FGF-2 for therapeutic angiogenesis.

J Biosci Bioeng

December 2024

Department of Macromolecular Science, Graduate School of Science, Osaka University, Toyonaka, Osaka 560-0043, Japan. Electronic address:

The fibroblast growth factor-2 (FGF-2) is a critical protein for biological processes such as angiogenesis and tissue regeneration. Recently, hydrogels based on semi-synthetic sulfated polysaccharides have been developed for the controlled delivery of FGF-2. These affinity-based FGF-2 carriers utilizing hydrogels based on sulfated polysaccharides enable sustained delivery of FGF-2, yet choice of materials is limited.

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Waterlogging is expected to become a more prominent yield restricting stress for barley as rainfall frequency is increasing in many regions due to climate change. The duration of waterlogging events in the field is highly variable throughout the season, and this variation is also observed in experimental waterlogging studies. Such variety of protocols make intricate physiological responses challenging to assess and quantify.

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Abstracts accepted for the 2021-2023 French Orthopaedic and Traumatology Society meetings: Proportion of women submitters.

Orthop Traumatol Surg Res

September 2024

University Institute for Spine Surgery, Armand Trousseau Hospital, Sorbonne Université, 26 avenue du Dr Netter, 75012 Paris, France.

Background: Women are underrepresented in orthopaedic and trauma surgery worldwide, with proportions of 4%-17% across countries and 9.1% in France. The annual meeting of the French Society for Orthopaedic and Trauma Surgery (SOFCOT) provides opportunities for quantifying the representation of women, which has not yet been accurately evaluated.

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Maternal exposure to pesticides induces perturbations in the gut microbiota and blood-brain barrier of dams and the progeny, prevented by a prebiotic.

Environ Sci Pollut Res Int

October 2024

PERITOX-Périnatalité et Risques Toxiques-UMR_I 01 UPJV/INERIS, Centre Universitaire de Recherche en Santé, CURS-UPJV, University of Picardie Jules Verne, CEDEX 1, 80054, Amiens, France.

Article Synopsis
  • Exposure to pesticide residues like chlorpyrifos (CPF) during the first 1000 days of life disrupts gut microbiota balance, which may lead to health issues in offspring by affecting organs such as the blood-brain barrier (BBB).
  • In a study with female rats, CPF exposure decreased beneficial gut bacteria and caused bacteria to move to other organs, compromising tight junctions in brain microvessels.
  • The study also found that inulin, a prebiotic, helped to restore microbial balance and gene expression levels, indicating its potential as a therapeutic strategy to protect against pesticide-related health effects.
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  • The differentiation of megakaryocytes (Mks) from haematopoietic stem cells is influenced by mechanical forces, with PIEZO1 playing a key role in sensing these forces.
  • Gain-of-function mutations in PIEZO1 lead to hereditary xerocytosis, highlighting its importance in thrombosis and potentially affecting platelet formation.
  • This study demonstrated that activating PIEZO1 with YODA1 initially reduces Mk maturation but later promotes endomitosis and proplatelet formation, indicating a complex regulatory role for PIEZO1 in Mk development.
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The authors reply.

Kidney Int

October 2024

Centro de Tecnologia da Informação (CTI) Renato Archer, Campinas, São Paulo, Brazil.

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