Template Free Anisotropically Grown Gold Nanocluster Based Electrochemical Immunosensor for Ultralow Detection of Cardiac Troponin I.

Anisotropic gold nanostructures have fascinated with their exceptional electronic properties, henceforth exploited for the fabrication of electrochemical sensors. However, their synthesis approaches are tedious and often require a growth template. Modern lifestyle has caused an upsurge in the risk of heart attack and requires urgent medical attention.

Exploring Microbial-Based Green Nanobiotechnology for Wastewater Remediation: A Sustainable Strategy.

Water scarcity due to contamination of water resources with different inorganic and organic contaminants is one of the foremost global concerns. It is due to rapid industrialization, fast urbanization, and the low efficiency of traditional wastewater treatment strategies. Conventional water treatment strategies, including chemical precipitation, membrane filtration, coagulation, ion exchange, solvent extraction, adsorption, and photolysis, are based on adopting various nanomaterials (NMs) with a high surface area, including carbon NMs, polymers, metals-based, and metal oxides.

An ultrasensitive electrochemical DNA biosensor for monitoring Human papillomavirus-16 (HPV-16) using graphene oxide/Ag/Au nano-biohybrids.

A DNA-based electrochemical biosensor has been developed herein for the detection of Human papillomavirus-16 (HPV-16). HPV-16 is a double-stranded, non-enveloped, epitheliotropic DNA virus which responsible for cervical cancer. In this proposed biosensor, an indium tin oxide (ITO) coated glass electrode was modified for sensing HPV-16 using graphene oxide and silver coated gold nanoparticles.

Intranasally Co-administered Berberine and Curcumin Loaded in Transfersomal Vesicles Improved Inhibition of Amyloid Formation and BACE-1.

Selective permeability of the blood-brain barrier restricts the treatment efficacy of neurologic diseases. Berberine (BBR) and curcumin (CUR)-loaded transferosomes (TRANS) were prepared for the effective management of Alzheimer's disease (AD). The study involved the syntheses of BBR-TRANS, CUR-TRANS, and BBR-CUR-TRANS by the film hydration method.

Enhancing Electrocardiogram Classification with Multiple Datasets and Distant Transfer Learning.

Electrocardiogram classification is crucial for various applications such as the medical diagnosis of cardiovascular diseases, the level of heart damage, and stress. One of the typical challenges of electrocardiogram classification problems is the small size of the datasets, which may lead to limitation in the performance of the classification models, particularly for models based on deep-learning algorithms. Transfer learning has demonstrated effectiveness in transferring knowledge from a source model with a similar domain and can enhance the performance of the target model.

Privacy protection framework for face recognition in edge-based Internet of Things.

Edge computing (EC) gets the Internet of Things (IoT)-based face recognition systems out of trouble caused by limited storage and computing resources of local or mobile terminals. However, data privacy leak remains a concerning problem. Previous studies only focused on some stages of face data processing, while this study focuses on the privacy protection of face data throughout its entire life cycle.

Biodegradable PEG-PCL Nanoparticles for Co-delivery of MUC1 Inhibitor and Doxorubicin for the Confinement of Triple-Negative Breast Cancer.

Unlabelled: Combating triple-negative breast cancer (TNBC) is still a problem, despite the development of numerous drug delivery approaches. Mucin1 (MUC1), a glycoprotein linked to chemo-resistance and progressive malignancy, is unregulated in TNBC. GO-201, a MUC1 peptide inhibitor that impairs MUC1 activity, promotes necrotic cell death by binding to the MUC1-C unit.

Effects of Heavy Ion Irradiation on the Thermoelectric Properties of In(TeSe) Thin Films.

Ion irradiation is an exceptionally effective approach to induce controlled surface modification/defects in semiconducting thin films. In this investigation, ion-irradiated Se-Te-based compounds exhibit electrical transport properties that greatly favor the transformation of waste heat into electricity. Enhancements of both the Seebeck coefficient (S) and the power factor (PF) of In(TeSe) films under 120 MeV Ni ion irradiation were examined.

Selenium-based nanomaterials for biosensing applications.

The unique chemical and physical features of nanomaterials make them ideal for developing new and better sensing devices, particularly biosensors. Various types of nanoparticles, including metal, oxide, and semiconductor nanostructures, have been utilized to manufacture biosensors, and each kind of nanoparticle plays a unique role in the sensing system. Nanoparticles provide critical roles such as immobilizing biomolecules, catalyzing electrochemical processes, enhancing electron transport between electrode surfaces and proteins, identifying biomolecules, and even functioning as the reactant for the catalytic reaction.

Towards hospital-on-chip supported by 2D MXenes-based 5 generation intelligent biosensors.

Existing public health emergencies due to fatal/infectious diseases such as coronavirus disease (COVID-19) and monkeypox have raised the paradigm of 5 generation portable intelligent and multifunctional biosensors embedded on a single chip. The state-of-the-art 5 generation biosensors are concerned with integrating advanced functional materials with controllable physicochemical attributes and optimal machine processability. In this direction, 2D metal carbides and nitrides (MXenes), owing to their enhanced effective surface area, tunable physicochemical properties, and rich surface functionalities, have shown promising performances in biosensing flatlands.

Emergence of MXene and MXene-Polymer Hybrid Membranes as Future- Environmental Remediation Strategies.

The continuous deterioration of the environment due to extensive industrialization and urbanization has raised the requirement to devise high-performance environmental remediation technologies. Membrane technologies, primarily based on conventional polymers, are the most commercialized air, water, solid, and radiation-based environmental remediation strategies. Low stability at high temperatures, swelling in organic contaminants, and poor selectivity are the fundamental issues associated with polymeric membranes restricting their scalable viability.

Bio-Vitrimers for Sustainable Circular Bio-Economy.

The aim to achieve sustainable development goals (SDG) and cut CO-emission is forcing researchers to develop bio-based materials over conventional polymers. Since most of the established bio-based polymeric materials demonstrate prominent sustainability, however, performance, cost, and durability limit their utilization in real-time applications. Additionally, a sustainable circular bioeconomy (CE) ensures SDGs deliver material production, where it ceases the linear approach from production to waste.

SARS-CoV-2-on-Chip for Long COVID Management.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a "wicked evil" in this century due to its extended progression and huge human mortalities. Although the diagnosis of SARS-CoV-2 viral infection is made simple and practical by employing reverse transcription polymerase chain reaction (RT-PCR) investigation, the process is costly, complex, time-consuming, and requires experts for testing and the constraints of a laboratory. Therefore, these challenges have raised the paradigm of on-site portable biosensors on a single chip, which reduces human resources and enables remote access to minimize the overwhelming burden on the existing global healthcare sector.

Application of perovskites in bioimaging: the state-of-the-art and future developments.

Background: Recently, the development of perovskite-based nanocrystals for sustainable applications in bioimaging and clinical diagnostics have become a very active area of research. From 2D hybrid to zero-dimensional quantum dots (QDs), perovskites along with a variety of characteristic features, specifically non-linear optoelectronics properties, have attracted enormous research attention. These characteristics can be tuned by the type of cations or anions and their ratio used in host perovskites.

Biopolymer-based electrospun fibers in electrochemical devices: versatile platform for energy, environment, and health monitoring.

Electrochemical power tools are regarded as essential keys in a world that is becoming increasingly reliant on fossil fuels in order to meet the challenges of rapidly depleting fossil fuel supplies. Additionally, due to the industrialization of societies and the growth of diseases, the need for sensitive, reliable, inexpensive, and portable sensors and biosensors for noninvasive monitoring of human health and environmental pollution is felt more than ever before. In recent decades, electrospun fibers have emerged as promising candidates for the fabrication of highly efficient electrochemical devices, such as actuators, batteries, fuel cells, supercapacitors, and biosensors.

Comprehensive analyses of image forgery detection methods from traditional to deep learning approaches: an evaluation.

The digital image proves critical evidence in the fields like forensic investigation, criminal investigation, intelligence systems, medical imaging, insurance claims, and journalism to name a few. Images are an authentic source of information on the internet and social media. But, using easily available software or editing tools such as Photoshop, Corel Paint Shop, PhotoScape, PhotoPlus, GIMP, Pixelmator, etc.

Bioelectronic medicines: Therapeutic potential and advancements in next-generation cancer therapy.

Bioelectronic medicine has tremendous potential in biomedical sector including oncology research, research on biomechanical and chemical properties of cells and biomaterials, healing bone tissue using electromagnetic fields, and understanding bioelectrical properties of aging. Bioelectronic medicine uses electricity to alter the body's electrical communication systems in order to treat various illnesses. The bioelectric circuits produce an endogenous electric field and a resting voltage when the cells are functioning and communicating.

Biobased and Programmable Electroadhesive Metasurfaces.

Electroadhesion has shown the potential to deliver versatile handling devices because of its simplicity of actuation and rapid response. Current electroadhesion systems have, however, significant difficulties in adapting to external objects with complex shapes. Here, a novel concept of metasurface is proposed by combining the use of natural fibers (flax) and shape memory epoxy polymers in a hygromorphic and thermally actuated composite (HyTemC).

Thermoelectric and Photovoltaic Properties of Mn-Doped Kesterite CuZnMnSnSe.

The semiconductor CuZnSnSe (CZTSe) is a promising candidate for both thermoelectric and photovoltaic energy harvesting applications due to a combination of features such as direct band gap, high absorption coefficient, and low thermal conductivity. We report the solid-state synthesis and characterization of Mn-doped CuZnMnSnSe ( = 0, 0.05, 0.

ZnO/CeO Nanocomposites: Metal-Organic Framework-Mediated Synthesis, Characterization, and Estimation of Cellular Toxicity toward Liver Cancer Cells.

The Zinc-doped cerium oxide nanocomposite (ZnO/CeO NC) was synthesized using a metal-organic framework as a precursor through the combustion method. It was characterized by powder X-ray diffraction (PXRD), Fourier transform infrared spectroscopy (FTIR), field emission electron microscopy (FESEM), energy dispersive analysis (EDX), transmission electron microscopy (TEM), dynamic light scattering (DLS), and ξ-potential. The PXRD demonstrated the successful synthesis of ZnO/CeO NC with a crystallite size of 31.

Swift Heavy Ion-Induced Reactivity and Surface Modifications in Indium Thin Films.

As an energetic ion traverses a target material, it loses its energy through the processes of electronic energy loss ( ) and nuclear energy loss ( ). Controlled swift heavy ion (SHI) irradiation on solid targets produces its effects through both of these mechanisms, as a consequence of which modifications occur in the structure, surface morphology, and magnetic and optical properties, apart from ion implantation and ion-induced reactivity. A systematic investigation of these effects can be useful in developing standard protocols for creating desired effects in materials using specific ion beams.

Hydrogels for localized drug delivery: A special emphasis on dermatologic applications.

Skin disease treatment is a complex and time-consuming process due to the complex etiology, numerous side effects of conventional therapies, and difficulties in determining primary causes of the disease. Superficial wounds are often easy to treat. However, treatment of severe wounds caused by burn is challenging for clinicians.

Superparamagnetic and Perfect-Paramagnetic Zinc Ferrite Quantum Dots from Microwave-Assisted Tunable Synthesis.

The properties of quantum dot (QD)-size material depend directly upon its unit cell structure. Spinel zinc ferrite QD powder is produced via a one-pot microwave-assisted hydrothermal synthesis for just 5 min. Varying initial pH values of the preparation sol from 6 to 12 enlarges the Zn/Fe atomic ratio (by ca.

Effect of terephthalic acid functionalized graphene oxide on the molecular interaction, and mechanical and thermal properties of Hytrel polymer.

We report the effect of incorporating functionalized graphene oxide (terephthalic acid functionalized GO; GO--TPA) on the thermal and mechanical properties of Hytrel (HTL; a thermoplastic elastomeric polymer). Initially, the synthesis of GO--TPA was performed chemical methods and subsequently characterized using various spectroscopic and imaging techniques. The melt mixing technique was executed in preparing the nanocomposites of HTL/GO and HTL/GO--TPA.