Biosurfactant Production using URM 1150 and its Application in the Bioremediation of Coast Environments Impacted by Oil Spills.

Background: This study aimed to produce, characterize, and apply a biosurfactant as a bioremediation tool for oil-contaminated coastal environments.

Methods: The biosurfactant was produced in a medium containing 5.0% corn steep liquor and 1.

The Influence of Fluoxetine on the Sensorimotor Function of the Sciatic Nerve in Wistar Rats after Axonotmesis: An Experimental Animal Model.

Background: Fluoxetine, a serotonin reuptake inhibitor antidepressant, raises extracellular serotonin levels and promotes angiogenesis and neurogenesis. Numerous animal models have shown its beneficial effects on recovery from peripheral nerve injury.

Purpose: The primary objective of this study was to analyze the influence of fluoxetine on the sensory-motor function recovery of the sciatic nerve in Wistar rats after axonotmesis.

Bactericidal Metal-Organic Gallium Frameworks - Synthesis to Application.

Gallium, a trace metal not found in its elemental form in nature, has garnered significant interest as a biocide, given its ability to interfere with iron metabolism in bacteria. Consequently, several gallium compounds have been developed and studied for their antimicrobial properties but face challenges of poor solubility and formulation for delivery. Organizing the metal into three-dimensional, hybrid scaffolds, termed metal-organic frameworks (MOFs), is an emerging platform with potential to address many of these limitations.

Single-Leg Balance and Lower Limb Strength: Quantitative Analysis with the Balance Master System.

: This study investigates the relationship between lower limb strength and postural stability in single-leg stance using the Balance Master system. : The research involved 64 participants divided into sedentary and physically active groups based on metabolic equivalents of task (METs) values, normal weight, overweight, and obese according to body composition. Postural control was evaluated using the Sensory Organization Test.

Exploring the effects of climate change on child malnutrition: protocol for a scoping review.

Introduction: Rapid climate changes in the early 21st century have triggered a global syndemic intertwining obesity, undernutrition and climate change, profoundly affecting health, especially children. Despite increasing research, a significant gap persists in understanding the mechanisms linking climate change to child malnutrition, particularly in children under 5 years old. This protocol proposes a scoping review to address this gap, with the aim of mapping the available evidence on the relationship between climate change and malnutrition among children under 5 years old.

Synthesis of Silver Nanoparticles and Evaluation of Antimicrobial Activity Using the Aqueous Extract of Pterodon emarginatus Seeds.

The decline in research for new antimicrobials, combined with the rise in bacterial resistance, has become a critical issue that is expected to worsen over time. As an alternative, health sciences have integrated materials engineering to develop new bioactive compounds through the interaction of nanoparticles with plant-derived compounds. These compounds offer advantages such as high bioavailability and low cost, exemplified by , a plant native to the Brazilian Cerrado.

Evaluating efflux pump inhibition in Staphylococcus aureus 1199B strain using thiadiazine-derived compounds: In vitro and in silico approaches.

Thiadiazines are heterocyclic compounds known for some pharmacological activities. However, the ability of these compounds and their derivatives to act as antibacterial agents and inhibitors of the efflux system in resistant bacteria remains unknown. This study aims to evaluate the antibacterial and NorA efflux pump inhibitory activities of thiadiazine-derived compounds (IJ14, IJ15, IJ16, IJ17, IJ18, IJ19, and IJ20) against the Staphylococcus aureus 1199B strain.

Comparisons of approaches to pelvic floor muscle training for urinary incontinence in women.

Background: Pelvic floor muscle training (PFMT) is a recommended treatment for female stress, urgency, and mixed urinary incontinence. Training varies in exercise type (pelvic floor muscles contracting with and without other muscles), dose, and delivery (e.g.

The projected impacts of climate change and fishing pressure on a tropical marine food web.

Small-scale fisheries, especially those from developing countries, are vital for millions. Understanding the impact of environmental and human factors on fish stocks and yields and how they might change is crucial to ensure the sustainable use of aquatic resources. We developed an ecosystem model using Ecopath and Ecosim (EwE) to investigate changes in target species biomass and ecosystem attributes over 83 years (2017-2100) caused by different scenarios of fishing pressure and ocean warming in the Brazilian Northeastern continental shelf.

Comparative outcomes of video-assisted thoracic surgery versus open thoracic surgery in pediatric pulmonary metastasectomy: a systematic review and meta-analysis.

This meta-analysis aimed to compare the outcomes of video-assisted thoracic surgery (VATS) and open thoracotomy in pediatric patients undergoing pulmonary metastasectomy for various malignancies. We systematically searched PubMed, Embase, and Cochrane Library databases for studies comparing VATS and open thoracotomy in pediatric patients. The treatment effects for continuous outcomes were compared using mean differences (MDs), and binary endpoints were evaluated using odds ratios (ORs), with 95% confidence intervals (CIs).

Surveillance of Schmallenberg virus in cattle populations in Northeastern Brazil.

The objective of this study was to conduct a serological investigation of Schmallenberg virus (SBV) infection in cattle raised in the State of Alagoas. A total of 460 serum samples from the Agricultural Defense Agency of Alagoas (ADEAL) serum bank were analyzed. These samples were collected from unvaccinated cattle on 100 properties across 99 municipalities in Alagoas, representing the three mesoregions: Agreste, Leste, and Sertão.

Repeat competition and ecological shifts drive the evolution of the mobilome in Rhynchospora Vahl. (Cyperaceae), the holocentric beaksedges.

Background And Aims: Genomic changes triggered by polyploidy, chromosomal rearrangements, and/ or environmental stress are among factors that affect the activity of mobile elements, particularly Long Terminal Repeats Retrotransposons (LTR-RTs) and DNA transposons. Because these elements can proliferate and move throughout host genomes, altering the genetic, epigenetic and nucleotypic landscape, they have been recognized as a relevant evolutionary force. Beaksedges (Rhynchospora) stand out for their wide cosmopolitan distribution, high diversity (~400 spp.

The effect of telehealth on clinical outcomes in patients with hypertension and diabetes: A meta-analysis of 106,261 patients.

Introduction: Telemedicine, propelled by recent technological advancements, has transformed healthcare delivery, notably benefiting patients with chronic non-communicable diseases (NCDs) such as systemic arterial hypertension and diabetes mellitus. This meta-analysis of randomized clinical trials aimed to assess the efficacy of telehealth-based interventions on disease control rates and clinical parameters among NCD patients, including systolic and diastolic blood pressure (SBP and DBP), fasting blood glucose (FBG), and glycated hemoglobin (HbA1c) levels.

Methods: We conducted searches in PubMed, Scopus, Web of Science, and the Cochrane Database for interventional studies that compared tele-monitoring with usual care in patients with hypertension and type 2 diabetes mellitus.

Earlier diagnosis of peripheral neuropathy in primary care in Latin America using a simple screening tool (ACT).

Peripheral Neuropathy (PN) can significantly impair quality of life, but often remains undiagnosed due to limited clinic time, lack of specialist expertise and lack of patient awareness. There are several validated questionnaires for diagnosing PN, but the time taken to administer them in busy primary care clinics limits their utilization. A new, simpler questionnaire was developed following an advisory board meeting in Southeast Asia and was further refined and translated to Portuguese and Spanish following a second advisory board meeting in Latin America.

Association Between Physical Activity Levels and Symptoms of Temporomandibular Disorders in Office Workers: A Cross-Sectional Observational Study.

Background: Sedentary work is a potential health risk factor and may exacerbate painful complaints, while physical activity may serve as a preventive factor for the onset and worsening of musculoskeletal disorders. However, there is scarce evidence on how engaging in leisure physical activity may influence the reporting of temporomandibular dysfunction (TMD) symptoms.

Objective: To assess the association between the level of physical activity and TMD symptoms in office workers.

Viability of microencapsulated species of Trichoderma as a strategy to optimize use in biological control.

The increasing use of chemical fungicides without effective control of phytopathogens has led to the development of resistance in microorganisms. As a promising alternative, products formulated with Trichoderma have emerged for their sustainable and effective potential in integrated disease management. However, the predominant formulations do not offer the necessary protection against abiotic factors.

Antimicrobial and Anti-Inflammatory Activity of Bauhinia Pulchella Extract Fractions.

This study investigates the antimicrobial and anti-inflammatory activities of fractions from the stem extract of Bauhinia pulchella Benth. The ethanolic extract was fractionated using column adsorption chromatography, resulting in a hexane fraction (J1) and a dichloromethane fraction (J2), both rich in terpenes and steroids. Characterization was performed using gas chromatography coupled with mass spectrometry (GC-MS).

Lectin from microalgae: Non-toxic to human cells and effective against Leishmania.

New leishmanicidal products are needed for the treatment to be effective, since current drugs are toxic to healthy human/animal cells and have low efficacy against the parasite. Bioactive compounds from microalgae, such as lectins, can be explored as new anti-Leishmania candidates. This study aimed to evaluate the cytotoxic and anti-Leishmania action of the cell extract (CE) and lectin (CVU) from Chlorella vulgaris biomass.

Transmissible venereal tumour with encephalic metastasis in dogs.

From January 2000 to December 2023 the Laboratory of Animal Pathology of the Federal University of Campina Grande received 6,218 canine autopsy and biopsy submissions, with six (0.09%) autopsy cases diagnosed as transmissible venereal tumour (TVT) with encephalic metastases. The mean age of affected dogs (four females and two males) was 7 years.

Efficacy of caffeine as an ergogenic aid in multiple cycling time trials.

Introduction: Evidence that caffeine supplementation is effective to improve performance in cycling time trials has been obtained in single rather than multiple time trials. We investigated whether 5 mg.kg of caffeine enhanced performance in multiple 4 km cycling time trials (TT4km) conducted within the same day and across different days.

Genome-wide association study analysis of single nucleotide variants in associated with IL-6 inflammatory response in visceral leishmaniasis.

Elevated levels of IL-6 in plasma are associated with the severity of visceral leishmaniasis (VL). The clinical manifestations of VL vary among patients, influenced by host factors and the virulence of the parasite. Considering that severe VL may result from an exaggerated inflammatory response, this study investigated whether IL-6 could serve as a biomarker to identify pro-inflammatory virulence factors.

Artificial Neural Network-Assisted Facial Analysis for Planning of Orthognathic Surgery.

Background: Facial analysis for orthognathic surgery aims to identify facial features and determine how occlusion should be corrected to achieve facial balance. Several artificial neural networks have been developed to detect facial landmarks; however, no publications have reported the application of neural networks to measure facial proportions specifically for orthognathic surgery planning. Objectives: To develop a computer program that automates facial measurements through photograph capture, as well as to present the development stages of the program and the test results evaluating its effectiveness.