Single versus two dental implants retained mandibular over dentures: comparison of function, patient satisfaction, oral health-related quality of life and success of treatment.

Objective: To compare the effectiveness of prosthetic rehabilitation of edentulous patients using conventional complete dentures (CD), single median dental implant retained over dentures (SIMOD) with over dentures retained by two dental implants (TIMOD).

Methods: Thirty completely edentulous patients (fifteen each arm) presented to the Faculty of Dental Sciences, University of Peradeniya were randomly selected for the SIMOD or TIMOD groups. Patients were initially provided with CD.

Early pregnancy diagnosis in cows using corpus luteum blood flow analysis based on colour Doppler ultrasonography and mRNA analysis.

Background: Reproductive efficiency is paramount in the dairy industry, where early pregnancy detection of dairy cows will allow to detect the non-pregnant animals early, thus enabling to re-synchronize them and getting them pregnant leading to decrease in calving interval, which, in turn, is critical for maximizing productivity and economic gain. The objective of this study was to evaluate the colour Doppler ultrasonography (CDUS) and peripheral blood leukocytes (PBLs)-based pregnancy-associated biomarker mRNAs expression for the earliest detection of pregnancy status in the dairy cows at post insemination. Intensively managed animals were ovulation synchronized and subjected to timed artificial insemination (TAI).

Assessment of diagnostic accuracy and inter-pathologist agreement in telecytology performed for canine round cell tumours using images captured by a smartphone camera.

Neoplasia is a common disease in companion animals. Rapid and accurate diagnosis of neoplasia often leads to a better disease outcome. Cytology is an inexpensive and minimally invasive method frequently used to diagnose neoplasia.

Control of dengue larvae of Aedes aegypti and Aedes albopictus using the larvicidal bioactive compounds in different plant extracts and plant extract-mediated nanoparticles.

Background: Dengue is a devastating viral disease transmitted by mosquito vectors of Aedes aegypti and Aedes albopictus. Mosquito populations thrive in favourable breeding conditions, making mosquito control vital. Eliminating larval populations is the most effective method compared with other mosquito control methods.

Unravelling a mystery of hypokalemic hypertension- a rare case report of a reninoma.

Background: Reninoma is a rare cause of secondary hypertension, which can be cured with surgery if identified early before any target organ damage occurs. It leads to hypokalaemia and hypertension and typically responds well to treatment with renin-angiotensin-aldosterone system blockers. However, confirmation of the diagnosis and the localisation of this rare culprit lesion can be challenging.

Burden of rotavirus and adenovirus gastroenteritis in children and adults hospitalized in two geo-climatically different provinces of Sri Lanka.

Acute gastroenteritis is common in infants and children of Sri Lanka. There is limited information on the burden of rotavirus gastroenteritis in infants and children in Sri Lanka but none in adults. Adenovirus gastroenteritis is not previously reported in Sri Lanka.

Advancement in predictive biomarkers for gestational diabetes mellitus diagnosis and related outcomes: a scoping review.

Objective: Gestational diabetes mellitus (GDM) is a metabolic disorder associated with adverse maternal and neonatal outcomes. While GDM is diagnosed by oral glucose tolerance testing between 24-28 weeks, earlier prediction of risk of developing GDM via circulating biomarkers has the potential to risk-stratify women and implement targeted risk reduction before adverse obstetric outcomes. This scoping review aims to collate biomarkers associated with GDM development, associated perinatal outcome and medication requirement in GDM.

What do women experiencing domestic violence expect from healthcare professionals? A qualitative study in Sri Lanka.

Objectives: For healthcare professionals (HCPs) to provide optimal support for women experiencing domestic violence (DV), it is important to understand what type of support women expect from HCPs. The objective of this study was to explore what kind of support women who experienced DV in Sri Lanka expect from HCPs.

Design: A qualitative descriptive design was used.

Membrane fouling characteristics and cleaning strategies for rural decentralized nanofiltration drinking water station based on groundwater source.

Groundwater is an important source of drinking water in rural areas. In this study, the performance of water purificat ion in a rural water station equipped with nanofiltration (NF) membranes based groundwater source was investigated, as well as the contamination morphology, foulant composition and distribution characteristics of NF membrane. Results showed that significant differences of membrane foulants were observed in different sections of NF membrane.

Thermogenic adipose tissues: promising therapeutic targets for metabolic diseases: Thermogenic fats and obesity.

The ongoing increase in the prevalence of obesity and its comorbidities such as cardiovascular disease, type 2 diabetes (T2D) and dyslipidemia warrants discovery of novel therapeutic options for these metabolic diseases. Obesity is characterized by white adipose tissue expansion due to chronic positive energy balance as a result of excessive energy intake and/or reduced energy expenditure. Despite various efforts to prevent/reduce obesity including lifestyle and behavioral interventions, surgical weight reduction approaches and pharmacological methods, there has been limited success in significantly reducing obesity prevalence.

Situational analysis of pesticide poisoning and perceptions of autoinjector devices in rural communities in Sri Lanka - a study protocol.

Intentional and unintentional pesticide poisoning is an important public health problem, especially in low- and middle-income countries. Individuals who have been exposed to toxic pesticides, particularly organophosphorus insecticides, need early treatment. Atropine autoinjector devices offer a potential solution, allowing storage of effective treatment near agricultural workers' fields and homes that could be reached within minutes by the worker or fellow villagers to provide first-line emergency care.

Elucidating the potential of Annona muricata L. grown in Sri Lanka to be used in developing an anticancer drug against colorectal and breast cancers.

Background: Since ancient times many traditional medicine systems around the world have been using different parts of Annona muricata L. (AM), to treat cancer. Indeed, numerous in vitro and in vivo studies also have shown anticancer properties of different solvent extracts of different parts of AM.

Coinfection with Dolphin Morbillivirus (DMV) and Gammaherpesvirus in a Spinner Dolphin () Stranded in Sri Lanka.

Following the X-Press Pearl maritime disaster off the coast of Sri Lanka, a stranded spinner dolphin () was recovered, and the cause of death was investigated. Post-mortem examinations revealed evidence of by-catch, but a natural coinfection with dolphin morbillivirus (DMV) and gammaherpesvirus was detected by further analyses, marking the first documented case of a dual viral infection in this species within the region. Molecular diagnostics, including PCR and sequencing, were performed on tissue imprints collected on FTA cards, confirming the presence of DMV in the prescapular lymph node and gammaherpesvirus in the lesions in the oral cavity.

Cannabinoids as Antibacterial Agents: A Systematic and Critical Review of In Vitro Efficacy Against and .

Background: Two major bacterial pathogens, and , are becoming increasingly antibiotic-resistant. Despite the urgency, only a few new antibiotics have been approved to address these infections. Although cannabinoids have been noted for their antibacterial properties, a comprehensive review of their effects on these bacteria has been lacking.

Effect of Cooling Rate on Properties of Beeswax and Stearic Acid Oleogel Based on Rice Bran Oil and Sesame Oil.

This study aimed to investigate how varying cooling rate impacts the characteristics of oleogels prepared using a sesame oil and rice bran oil blend (5:6, /) using a combination of beeswax and stearic acid (3:1, / at 12%, /) as the oleogelators. The study assessed three different cooling rates-0.5, 1.