91 results match your criteria: "University of Pais Vasco[Affiliation]"

This study aims to investigate (a) the mediating role of overparenting between father's educational level and children's school problems, and (b) the joint moderating role of children's gender and surgency in the indirect relationship between father's educational level and school problems. Participants were 203 school children, 96 boys (47.3%) and 107 girls (52.

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Article Synopsis
  • The study investigates the genetic factors linked to severe COVID-19, specifically focusing on hospitalized cases in admixed Americans.
  • Researchers conducted the largest genome-wide association study (GWAS) for COVID-19 hospitalization in this population, identifying four significant genetic associations, including two novel loci found in Latin Americans.
  • The findings highlight the importance of including diverse populations in genomic research, aiming to improve understanding of genetic risks associated with COVID-19 across different ethnic groups.
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Individuals with dementia and neurodegenerative diseases (NDDs) often suffer from cardiovascular diseases (CVDs). Neuroinflammation driven by conditions involved in CVDs is linked to disruptions in the central nervous system triggering immune reactions, perpetuating an "inflammatory-like" environment. The Mediterranean diet (MedDiet), known for its anti-inflammatory and antioxidant properties, has been proposed as a key factor to attenuate these risks.

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Generalizability Theory in the Evaluation of Psychological Profile in Track and Field.

Sports (Basel)

May 2024

Department of Social Psychology, Social Work, Anthropology and East Asian Studies, University of Málaga, 29071 Málaga, Spain.

Article Synopsis
  • - Generalizability theory (GT) is applied in sports research to enhance validity, reliability, and generalizability, but there's limited study on psychological profiles in this context.
  • - This study focuses on identifying sources of variability and estimating optimal measurement designs for assessing psychological profiles in track and field, using a sample of 470 participants averaging 32 years old.
  • - Analysis confirms high reliability and generalizability for psychological factors like flow, motivation, self-confidence, and psychological skills, emphasizing the importance of rigorous validation in sports psychological counseling.
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González-Cano, H, Martín-Olmedo, JJ, Baz-Valle, E, Contreras, C, Schoenfeld, BJ, García-Ramos, A, Jiménez-Martínez, P, and Alix-Fages, C. Do muscle mass and body fat differ between elite and amateur natural physique athletes on competition day? A preliminary, cross-sectional, anthropometric study. J Strength Cond Res 38(5): 951-956, 2024-Natural physique athletes strive to achieve low body fat levels while promoting muscle mass hypertrophy for competition day.

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Bodybuilding is characterized by high-rates of sport supplementation. This is the first study to compare the supplementation patterns of winners (WB) and non-winners (NWB) among international natural bodybuilders during contest preparation. Fifty-six natural bodybuilders (5 women) (age = 28.

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Community-acquired pneumonia represents the third-highest cause of mortality in industrialized countries and the first due to infection. Although guidelines for the approach to this infection model are widely implemented in international health schemes, information continually emerges that generates controversy or requires updating its management. This paper reviews the most important issues in the approach to this process, such as an aetiologic update using new molecular platforms or imaging techniques, including the diagnostic stewardship in different clinical settings.

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The aim of this study was to explore the effects of mental fatigue from smartphone use and Stroop task on bench press force-velocity (F-V) profile, one-repetition maximum (1RM), and countermovement jump (CMJ) performance. Twenty-five trained subjects (age = 25.8 ± 5.

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This study aimed to explore the effects of mental fatigue (MF) induced by an incongruent Stroop task (ST) and by using social media (SM) compared to watching a documentary (control) on dynamic resistance training. Twenty-one resistance-trained males attended three identical experimental sessions with the only difference of the randomized cognitive task (ST, SM, or control). Each session consisted of (a) baseline MF and motivation visual analogue scale responses, (b) cognitive task, (c) postvisual analogue scale responses, (d) warm-up, and (e) resistance training based on three sets of bench press at 65% of one-repetition maximum till concentric failure.

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Palliative patients require several types of care to improve their quality of life as much as possible, and valid and reliable assessment instruments are essential. The objective of this study is the Spanish validation of the Functional Assessment Chronic Illness Therapy-Palliative Care (FACIT-PAL) and its abbreviated version, FACIT-PAL-14, in palliative care patients. FACIT-PAL and FACIT-PAL-14 were translated into Spanish and administered to 131 terminal oncology patients in home palliative care units, hospital palliative care units, health center teams, and social health centers.

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Article Synopsis
  • A study was conducted to investigate the attitudes of nursing students in Spanish universities towards organ donation and transplantation, identifying key factors that influence their opinions.
  • The study surveyed 10,566 nursing students across 52 faculties, revealing that 78% of participants were willing to donate their organs after death.
  • Factors associated with a positive attitude included engagement in discussions about organ donation, the favorable opinions of family members, and having a good self-assessment of information on the topic.
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Novel genes and sex differences in COVID-19 severity.

Hum Mol Genet

November 2022

Centro Nacional de Genotipado (CEGEN), Universidade de Santiago de Compostela, 15706 Santiago de Compostela, Spain.

Article Synopsis
  • A genome-wide study involving nearly 12,000 COVID-19 positive cases in Spain identified significant genetic variants linked to hospitalization, with specific loci associated with males (3p21.31, 21q22.11) and females (9q21.32 near TLE1).
  • A second phase combined data with an additional cohort, revealing two new risk loci (9p13.3, 19q13.12) related to candidate genes AQP3 and ARHGAP33, and confirmed earlier findings in males for some loci.
  • The analysis highlighted genetic differences in COVID-19 severity between sexes and ages, with more pronounced heritability in males, particularly those over
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Multi-omic alterations of the SWI/SNF complex define a clinical subgroup in lung adenocarcinoma.

Clin Epigenetics

March 2022

Department of Biochemistry and Molecular Biology I, University of Granada, Campus Fuentenueva s/n, 18071, Granada, Spain.

SWI/SNF complexes are major targets of mutations in cancer. Here, we combined multiple "-omics" methods to assess SWI/SNF composition and aberrations in LUAD. Mutations in lung SWI/SNF subunits were highly recurrent in our LUAD cohort (41.

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Quality of life (QoL) is a complex, ordinal endpoint with multiple conditioning factors. A predictive model of QoL after adjuvant chemotherapy can support decision making or the communication of information about the range of treatment options available. Patients with localized breast cancer (n = 219) were prospectively recruited at 17 centers.

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Introduction: The aim of this study was to analyze the associations between perceived social support and sociodemographic variables on coping strategies.

Methods: A prospective, cross-sectional, multicenter study was conducted in 404 women with resected, non-metastatic breast cancer. Participants completed questionnaires: perceived social support (MSPSS), coping strategies (Mini-MAC), and psychological distress (BSI-18).

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Impact of Obesity on Quality of Life, Psychological Distress, and Coping on Patients with Colon Cancer.

Oncologist

May 2021

Department of Clinical Psychology and Psychobiology, Faculty of Psychology, University of Barcelona, Barcelona, University of País Vasco, País Vasco, Spain.

Background: Despite the causal relationship between obesity and colon cancer being firmly established, the effect of obesity on the course of cancer calls for further elucidation. The objective of this study was to assess differences in clinical-pathological and psychosocial variables between obese and nonobese individuals with colon cancer.

Materials And Methods: This was a prospective, multicentric, observational study conducted from 2015-2018.

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Impact of adjuvant therapy toxicity on quality of life and emotional symptoms in patients with colon cancer: a latent class analysis.

Clin Transl Oncol

March 2021

Department of Medical Oncology, Hospital Universitario Central de Asturias, ISPA, University of Pais Vasco, Pais Vasco, Avenida Roma sn, 33011, Oviedo, Spain.

Objective: To identify distinct trajectories of toxicity in colorectal cancer (CRC) patients after adjuvant chemotherapy and its impact on quality of life (QoL) and psychological symptoms.

Methods: A prospective, multicenter study was conducted in 157 patients. A latent class analysis defined the unobserved latent constructs that can be predicted as symptom clusters, considering the intensity of four types of adverse events (AEs).

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Decline in fertility induced by economic recession in Spain.

Gac Sanit

June 2021

Health Information Systems Service, Barcelona Agency of Public Health, Barcelona, Spain; Department of Experimental and Health Sciences, University Pompeu Fabra, Barcelona, Spain; Biomedical Research Institute Saint Pau, Barcelona, Spain; CIBER of Epidemiology and Public Health (CIBERESP), Spain. Electronic address:

Objective: To describe trends in fertility in Spain before (pre-recession; 1998-2008) and during (recession period; 2009-2013) the economic crisis of 2008, taking into account women's age and regional unemployment in 2010.

Method: The study consisted of a panel design including cross-sectional ecological data for the 17 regions of Spain. We describe fertility trends in Spain in two time periods, pre-recession (1998-2008) and recession (2009-2013).

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Background: Left ventricle diastolic dysfunction (LVDD) is a common finding in high risk individuals, its presence being associated with reduced exercise capacity (EC). We assessed the prevalence of LVDD, applying the 2016 guidelines of the American Society of Echocardiography (ASE)/European Association of Cardiovascular Imaging (EACVI), in a population with overweight/obesity and metabolic syndrome and its association with EC.

Methods And Results: This was a prospective, cross-sectional study of a cohort of 235 patients (mean age of 65 ± 5 years old and 33% female) without heart disease and an ejection fraction >50% who underwent a complete echocardiographic assessment and cardiopulmonary exercise testing.

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Lipid metabolism in adipose tissue and liver from diet-induced obese rats: a comparison between Wistar and Sprague-Dawley strains.

J Physiol Biochem

November 2018

Nutrition and Obesity Group, Department of Nutrition and Food Science, Faculty of Pharmacy and Lucio Lascaray Research Institute, University of País Vasco (UPV/EHU), Vitoria, Spain.

Some researchers have proposed important variations in adipose tissue among different strains of rats and mice in response to a high-caloric (hc) diet, but data concerning the mechanisms underlying these differences are scarce. The aim of the present research was to characterize different aspects of triacylglycerol (TG) metabolism and clock genes between Sprague-Dawley and Wistar rats. For this purpose, 16 male Sprague-Dawley and 16 male Wistar rats were divided into four experimental groups (n = 8) and fed either a normal-caloric (nc) diet or a hc diet for 6 weeks.

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Background: The use of resveratrol as a dietary supplement is limited because it is easily oxidized and, after oral ingestion, it is metabolized into enterocytes and hepatocytes. Thus, new formulations are needed in order to improve its oral bioavailability.

Objective: The objective of this study was to develop and characterize a gastro-resistant formulation of resveratrol for oral administration as a dietary supplement.

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The value of lncRNA and as a prognostic factor for survival of lung adenocarcinoma.

Oncotarget

March 2020

Centre for Genomics and Oncological Research, PTS Granada, Centro Pfizer - Universidad de Granada - Junta de Andalucía de Genómica e Investigación Oncológica (GENYO), Granada, Spain.

It is increasingly evident that non-coding RNAs play a significant role in tumour development. However, we still have a limited knowledge of the clinical significance of long non-coding RNAs (lncRNAs) in lung cancer. The is a long coding RNA (also named ) located in the vicinity of the protein-coding gene at 16q24.

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Overweight and obesity have been steadily increasing in recent years and currently represent a serious threat to public health. Few human studies have investigated the relationship between polyphenol intake and body weight. Our aim was to assess the relationship between urinary polyphenol levels and body weight.

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Novel Insights into the Multiple Sclerosis Risk Gene ANKRD55.

J Immunol

June 2016

Neurogenomiks Laboratory, University of the Basque Country (University of Pais Vasco/Euskal Herriko University), 48170 Zamudio, Spain; Achucarro Basque Center for Neuroscience, 48170 Zamudio, Spain; IKERBASQUE, Basque Foundation for Science, 48013 Bilbao, Spain

An intronic variant in ANKRD55, rs6859219, is a genetic risk factor for multiple sclerosis, but the biological reasons underlying this association are unknown. We characterized the expression of ANKRD55 in human PBMCs and cell lines. Three ANKRD55 transcript variants (Ensembl isoforms 001, 005, and 007) could be detected in PBMCs and CD4(+) T cells but were virtually absent in CD8(+), CD14(+), CD19(+), and CD56(+) cells.

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Surface heterogeneity affects the behavior of nanoparticles at liquid interfaces. To gain a deeper understanding on the details of these phenomena, we have measured the interfacial activity and contact angle at water/decane interfaces for three different types of nanoparticles: homogeneous poly(methyl methacrylate) (PMMA), silica functionalized with a capping ligand containing a methacrylate terminal group, and Ag-based Janus colloids with two capping ligands of different hydrophobicity. The interfacial activity was analyzed by pendant drop tensiometry, and the contact angle was measured directly by freeze-fracture shadow-casting cryo-scanning electron microscopy.

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