3 results match your criteria: "University of P.J. Safarik Kosice[Affiliation]"
RSC Adv
October 2018
Department of Analytical Chemistry, Uzhhorod National University Uzhhorod UA-88000 Ukraine
A novel, simple, sensitive and selective method for the indirect spectrophotometric determination of chromium(vi) was developed on the basis of vortex-assisted liquid-liquid microextraction (VALLME) of an ion association pair formed between the triiodide anion (I ) and cationic dye Astrazone Brilliant Red 4G (ABR). The indirect spectrophotometric determination of chromium(vi) was based on the redox-reaction of Cr(vi) with iodide and formed I . The triiodide anion was determined spectrophotometrically at 530 nm following VALLME of an ion association pair with ABR.
View Article and Find Full Text PDFPhytother Res
January 2009
Department of Experimental Medicine, Medical Faculty, University of P. J. Safarik Kosice, Slovak Republic.
Daunorubicin (DNR) is one of the most important antitumor agents belonging to the anthracycline group. However, its use is seriously limited by the development of cardiac toxicity. The present study was designed to investigate the effects of quercetin, pycnogenol and naringenin on daunorubicin-induced cytoxicity in H9c2 cells.
View Article and Find Full Text PDFPhytother Res
February 2006
Department of Experimental Medicine, Medical Faculty, University of P.J. Safarik Kosice, Slovak Republic.
Flavonoids are an ubiquitous group of polyphenolic substances with varied chemical structures present in foods of plant origin and act as free radical scavenging and chelating agents with a variety of biological activities. Using a model of spontaneously beating, cultured adult rat cardiomyocytes, this study examined the cardioprotective role of quercetin, naringenin, pycnogenol and a model antioxidant, trolox, against daunorubicin-induced toxicity. Cardiomyocyte protection was assessed by MTT test and extracellular lactate dehydrogenase detection.
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