3 results match your criteria: "University of Oviedo Medical School[Affiliation]"
No gender differences in the 24-month course of non-invasive liver fibrosis markers after DAA therapy in HCV-mono and HCV/HIV-coinfected patients.
Sci Rep
March 2024
Infectious Diseases-HIV Unit, Hospital Universitario Central de Asturias, University of Oviedo Medical School, Oviedo, Spain.
Untreated HCV mono and HCV/HIV coinfected women have lower degrees of liver fibrosis (LF) compared to men. Direct acting antiviral (DAA) therapy attains viral eradication in > 90% of patients with progressive LF decline in parallel. Gender-related differences in LF regression in the long term assessed by non-invasive liver fibrosis markers (NILFM) in HCV mono and HCV/HIV coinfected after DAA treatment have not been explored so far.
View Article and Find Full Text PDFThe TINCR ubiquitin-like microprotein is a tumor suppressor in squamous cell carcinoma.
Nat Commun
March 2023
Institute for Cancer Genetics, Columbia University, New York, NY, USA.
Article Synopsis
- The TINCR gene is specifically expressed in epithelial tissues and plays a role in skin cell differentiation and wound healing, despite being initially identified as a long non-coding RNA.
- Recent findings suggest that TINCR functions as a tumor suppressor in squamous cell carcinoma (SCC), with its expression increasing in response to UV damage in a TP53-dependent way.
- Decreased levels of TINCR are linked to skin and head/neck SCCs, as knockout mice show faster tumor development, and genetic analyses reveal mutations in TINCR in clinical SCC samples, confirming its tumor-suppressing capability.
Effect of streptozotocin-induced diabetes and islet transplantation in proximal skeletal muscle: a histochemical and morphometric analysis.
J Lab Clin Med
June 1994
Department of Surgery, University of Oviedo Medical School, Spain.
The effect of pancreatic islet transplantation on the development of diabetic myopathy in streptozotocin-induced diabetic Lewis rats was examined histochemically and morphometrically in a proximal striated (rectus femoris) muscle. Diabetes was induced by streptozotocin administration, and diabetic animals were transplanted by intraportal grafts 6 weeks later. Islet-transplanted rats returned to euglycemia usually within the first 24 hours after transplantation and remained euglycemic over the subsequent 12-week observation period.
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