14 results match your criteria: "University of Ottawa Library[Affiliation]"

Mifepristone as a non-emergency contraceptive among women of reproductive age: a protocol for systematic review and meta-analysis.

BMJ Open

December 2024

WHO Collaborating Centre, Division of Neonatology, Obstetrics, Gynecology, and Reproductive Health, Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.

Article Synopsis
  • Mifepristone is a well-researched contraceptive option that has shown promise in preventing pregnancy, yet there's no comprehensive review summarizing its effectiveness as a non-emergency contraceptive for cisgender girls and women of reproductive age.
  • A systematic review is being conducted to gather and analyze data from various databases, evaluating studies involving mifepristone to assess its contraceptive effectiveness specifically for this population.
  • The review will include data extraction, risk of bias evaluation, and potentially a meta-analysis of the findings, with the final results expected to provide clarity on mifepristone's role in non-emergency contraception by June 2024.
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In search of prosociality in rodents: A scoping review.

PLoS One

November 2024

Behavioural Neuroscience Group, School of Psychology, University of Ottawa, Ottawa, Ontario, Canada.

Studying prosociality in rodents can provide insight into brain mechanisms potentially related to neurodevelopmental disorders known to impact social behaviors (e.g., autism spectrum disorder).

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Older adults with subjective cognitive decline (SCD) have a higher risk of developing future cognitive decline than those without SCD. However, the association between SCD and objective cognitive performance remains unclear. This PRISMA 2020-compliant systematic review aims to provide a qualitative assessment of the longitudinal and cross-sectional relationship between SCD and objective cognitive performance in different cognitive domains, in neuropsychologically healthy, community-dwelling older adults (average age of 55 or older).

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Prevalence of patient partner authorship and acknowledgment in child health research publications: an umbrella review.

J Clin Epidemiol

December 2023

Child Health Evaluative Sciences, Hospital for Sick Children Research Institute, 686 Bay Street, Toronto, Ontario M5G 0A4, Canada; Department of Paediatrics, University of Toronto, Toronto, Ontario M5S 1A1, Canada.

Article Synopsis
  • Children and families are increasingly participating as equal partners in child health research, but there's a lack of attention to authorship issues in this area.
  • A study analyzed 230 articles from 12 systematic reviews on patient engagement in child health, finding that only 7% listed patient partners as authors, while 18% acknowledged them by name in the acknowledgment sections.
  • The results indicate that patient partners are more often acknowledged than formally credited as authors, highlighting the need for better understanding and support for their roles in research.
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Introduction: Ingestions with methanol, ethylene glycol, diethylene glycol, propylene glycol, and isopropanol are rare yet exceedingly dangerous conditions that may require emergent management with kidney replacement therapy. Little is known regarding short- and long-term kidney outcomes post-ingestion.

Objectives: To comprehensively synthesize existing evidence regarding short- and long-term kidney and other outcomes of adult patients following these poisonings.

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Objective: To identify impacts of patient and family engagement in child health research on the research process, research teams, and patient and family partners.

Study Design: A scoping review was conducted using the MEDLINE, Embase, Cumulative Index to Nursing and Allied Health Literature, PsycINFO, and Web of Science databases. English-language studies were included if they described ≥1 impact of patient and family engagement on child health research (age <18 years), researchers, or patient and family partners.

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Objectives: To identify what is known empirically about the screening, treatment and harm of exposure to neonatal hypoglycaemia.

Design: Scoping review that applied a preregistered protocol based on established frameworks.

Data Sources: Medline and Embase, up to 12 May 2020.

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Background: The early weeks of the COVID-19 pandemic brought multiple concurrent threats-high patient volume and acuity and, simultaneously, increased risk to health workers. Healthcare managers and decision-makers needed to identify strategies to mitigate these adverse conditions. This paper reports on the health workforce strategies implemented in relation to past large-scale emergencies (including natural disasters, extreme weather events, and infectious disease outbreaks).

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Neuropsychological Sequelae of Coronary Heart Disease in Women: A Systematic Review.

Neurosci Biobehav Rev

August 2021

Behavioural Neuroscience Group, School of Psychology, University of Ottawa, 136 Jean-Jacques Lussier, Ottawa, ON, K1N 6N5, Canada. Electronic address:

Heart disease, such as coronary heart disease (CHD), is the leading cause of death among aging women. However, over the past years, the mortality rate has declined, resulting in an increased number of CHD survivors. In this context, research has uncovered relationships between cardiovascular disease (CVD) and the development of neurodegenerative diseases, suggesting that CHD can act as a precursor.

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A systematic review of the Trier Social Stress Test methodology: Issues in promoting study comparison and replicable research.

Neurobiol Stress

November 2020

Behavioural Neuroscience Group, School of Psychology, University of Ottawa, 136 Jean-Jacques Lussier, Ottawa, On, K1N 6N5, Canada.

Since its development in 1993, the Trier Social Stress Test (TSST) has been used widely as a psychosocial stress paradigm to activate the sympathetic nervous system and hypothalamic-pituitary-adrenal axis (HPAA) stress systems, stimulating physiological functions (e.g. heart rate) and cortisol secretion.

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A systematic review and meta-analysis evaluating geriatric consultation on older trauma patients.

J Trauma Acute Care Surg

March 2020

From the University of Ottawa (D.E., B.G., L.K.); Clinical Epidemiology Program (W.C.), Ottawa Hospital Research Institute; Epidemiology Program, The Ottawa Hospital (D.E., J.M., S.F., J.L.); and University of Ottawa Library (K.F.), Ottawa, Ontario, Canada.

Background: Early involvement of geriatrics is recommended for older trauma patients.

Objective: This systematic review aimed to determine the impact of a geriatric assessment on mortality, hospital length of stay, discharge destination, and delirium incidence in patients 65 years and older admitted to a trauma center.

Methods: The protocol was developed according to Preferred Reporting Items for Systematic Review and Meta-analysis guidelines and registered in PROSPERO (CRD42019131870).

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Background: Overuse of head computed tomography (CT) for syncope has been reported. However, there is no literature synthesis on this overuse. We undertook a systematic review to determine the use and yield of head CT and risk factors for serious intracranial conditions among syncope patients.

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Clinical practice guidelines (CPGs) have been developed to summarize evidence about the management of rheumatoid arthritis (RA) and facilitate the uptake of evidence-based knowledge by consumers, health professionals, health administrators and policy makers. The objectives of this review was to assess the quality of CPGS on non-pharmacological management of RA with a standardized and validated instrument--the Appraisal of Guidelines for Research and Evaluation (AGREE II) tool and summarize the key recommendations from these CPGs. Scientific literature databases from 2001 to 2013 were systematically searched and a total of 13 CPGs for RA was identified.

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Clinical practice CPGs (CPGs) have been developed to summarize evidence related to the management of osteoarthritis (OA). CPGs facilitate uptake of evidence-based knowledge by consumers, health professionals, health administrators and policy makers. The objectives of the present review were: 1) to assess the quality of the CPGs on non-pharmacological management of OA; using a standardized and validated instrument--the Appraisal of Guidelines Research and Evaluation (AGREE II) tool--by three pairs of trained appraisers; and 2) to summarize the recommendations based on only high-quality existing CPGs.

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