47,016 results match your criteria: "University of Oslo[Affiliation]"
Scand J Gastroenterol
December 2024
Norwegian Coeliac Disease Research Centre, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Objectives: Concurrent type 1 diabetes (T1D) and celiac disease (CeD) pose challenges in insulin dosage adjustments and gluten-free dietary adherence. Urine testing for gluten immunogenic peptides (GIP) is a new method to detect gluten exposure within the last 3-12 h. Our aims were to compare gluten-free dietary adherence between T1D + CeD and CeD individuals and evaluate urinary GIP testing in an outpatient setting.
View Article and Find Full Text PDFSci Data
December 2024
University of Oslo, Department of Geosciences, Oslo, 0313, Norway.
Sea ice is a key element of the global Earth system, with a major impact on global climate and regional weather. Unfortunately, accurate sea ice modeling is challenging due to the diversity and complexity of underlying physics happening there, and a relative lack of ground truth observations. This is especially true for the Marginal Ice Zone (MIZ), which is the area where sea ice is affected by incoming ocean waves.
View Article and Find Full Text PDFBackground: Effective evidence-based interventions (EBI) are necessary to prevent and avoid negative life trajectories for children with mental health problems. Even though many EBIs prove effective when tested, few are successfully implemented and used in real-world clinical practice. As a result, many children and families do not receive the best care in due time or at all.
View Article and Find Full Text PDFInt J Sports Physiol Perform
December 2024
Department of Anesthesiology and Intensive Care, Akershus University Hospital, Lørenskog, Norway.
Purpose: Laboratory studies have demonstrated that manual dexterity decreases with increasing cold, which may adversely affect performance. Dexterity may be impaired by cooling of the hand, cooling of the lower motor neurons, and cognitive impairment. Wetsuits are commonly used in open-water swimming and are mandated in some situations.
View Article and Find Full Text PDFSeizure
December 2024
Department of Neurology, Oslo University Hospital, Oslo, Norway; ERGO - Epilepsy Research Group of Oslo, Oslo University Hospital, Oslo, Norway.
Psychoneuroendocrinology
December 2024
R&D department, Division of Mental Health Services, Akershus University Hospital, Lørenskog, Norway; Department of Psychiatry, University of Helsinki, Helsinki, Finland; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Objective: To investigate the association prenatal maternal depression and anxiety may have on the levels of neonatal hair steroids (i.e. cortisol, cortisone, and the cortisol/cortisone ratio) at birth.
View Article and Find Full Text PDFStem Cells
December 2024
Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo.
Pluripotent stem cells provide opportunities for treating injuries and previously incurable diseases. A major concern is the immunogenicity of stem cells and their progeny. Here, we have dissected the molecular mechanisms that allow natural killer (NK) cells to respond to human pluripotent stem cells, investigating a wide selection of activating and inhibitory NK cell receptors and their ligands.
View Article and Find Full Text PDFArch Orthop Trauma Surg
December 2024
Department of Orthopaedic Surgery and Traumatology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
J Neurol
December 2024
Department of Neurology, Inselspital Bern University Hospital and University of Bern, Bern, Switzerland.
Intravenous thrombolysis and mechanical thrombectomy reduce morbidity and improve functional outcome in ischemic stroke. However, acute recanalization therapies may increase the risk of symptomatic intracranial hemorrhage due to its effects on the brain tissue. An increasing proportion of patients with ischemic stroke are using direct oral anticoagulants (DOACs).
View Article and Find Full Text PDFHum Genet
December 2024
Department of Medical Genetics, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Neuron navigators (NAVs) are cytoskeleton-associated proteins well known for their role in axonal guidance, neuronal migration, and neurite growth necessary for neurodevelopment. Neuron navigator 3 (NAV3) is one of the three NAV proteins highly expressed in the embryonic and adult brain. However, the role of the NAV3 gene in human disease is not well-studied.
View Article and Find Full Text PDFJ Appl Lab Med
December 2024
Department of Diagnostic Imaging, Division of Diagnostics and Technology, Akershus University Hospital, Lørenskog, Norway.
Background: Myocardial fibrosis is associated with a poor outcome for patients with cardiovascular disease (CVD). Growth differentiation factor 15 (GDF-15) concentrations predict the risk of death in patients with CVD, but the underlying pathophysiological mechanisms are poorly understood. We aimed to assess the associations between biomarkers of cellular stress and inflammation (GDF-15), cardiac injury (cardiac troponin T [cTnT]), and stretch (N-terminal pro-B-type natriuretic peptide [NT-proBNP]), and subsequent focal and diffuse myocardial fibrosis assessed by cardiac magnetic resonance (CMR) imaging.
View Article and Find Full Text PDFActa Paediatr
December 2024
Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Aim: This national study focused on the individualised Heart Observation (HOBS) mobile phone app, which helps the parents of infants with severe congenital heart disease (CHD) with discharge preparations and decision making at home.
Methods: We enrolled two groups of parents from 2021 to 2023, during their child's initial hospitalisation at Oslo University Hospital, Norway. Measurements were carried out at baseline and one and four months after discharge.
Adv Mater
December 2024
Wuzhen Laboratory, Jiaxing, 314500, P. R. China.
Phase boundary is highly recognized for its capability in engineering various physical properties of ferroelectrics. Here, field-induced polarization rotation is reported in a high-performance (K, Na)NbO-based ferroelectric system at the rhombohedral-tetragonal phase boundary. First, the lattice structure is examined from both macroscopic and local scales, implementing Rietveld refinement and pair distribution function analysis, respectively.
View Article and Find Full Text PDFGlob Health Sci Pract
December 2024
Department of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda.
Introduction: We designed the Informed Health Choices (IHC) secondary school intervention and evaluated whether it improves students' ability to assess the trustworthiness of claims about treatment effects in Uganda. We conducted a process evaluation alongside a randomized trial to identify factors that may affect the implementation, fidelity, and scaling up of the intervention in Uganda. We also explored the potential adverse and beneficial effects of the intervention.
View Article and Find Full Text PDFGlob Health Sci Pract
December 2024
Centre for Epidemic Interventions Research, Norwegian Institute of Public Health, Oslo, Norway.
Introduction: We evaluated the Informed Health Choices secondary school intervention to help students in Kenya think critically about health choices. We conducted this process evaluation to explore if the intervention was implemented as planned, identify factors that facilitated or hindered implementation, potential benefits of the intervention, and how to scale up the intervention beyond the trial.
Methods: This was a mixed methods process evaluation nested in a cluster-randomized trial of the Informed Health Choices intervention.
Glob Health Sci Pract
December 2024
Centre for Epidemic Interventions Research, Norwegian Institute of Public Health, Oslo, Norway.
Introduction: We evaluated the Informed Health Choices secondary school intervention in a cluster randomized trial in Rwanda. The intervention was effective in helping students to think critically about health. In parallel to the trial, we conducted a process evaluation to assess factors affecting the implementation, impacts, and scale-up of the intervention.
View Article and Find Full Text PDFClin Biochem
December 2024
Ochsner Medical Center, New Orleans LA, USA; Ochsner Clinical School, University of Queensland School of Medicine, New Orleans, LA, USA.
Background: Secretoneurin, a member of the granin protein family, is associated with the risk of mortality in patients with acute and chronic heart failure. Secretoneurin may play an important role in cardiomyocyte calcium handling, suggesting that it may influence cardiac arrhythmia risk. We hypothesized that baseline and serial measurements of circulating secretoneurin are associated with the risk of incident ventricular tachyarrhythmias (VA) and death, and that serial measurement would provide prognostic information beyond baseline values.
View Article and Find Full Text PDFSci Total Environ
December 2024
Faculty of Drilling, Oil and Gas, AGH University of Krakow, al. Mickiewicza 30, 30-059, Krakow, Poland.
Carbon sequestration in deep saline aquifers is a promising strategy for reducing atmospheric CO emissions. However, salt precipitation triggered by the evaporation of formation brine into injected supercritical CO can cause injectivity and containment issues in near-wellbore regions. Predicting the distribution of precipitated salts and their impact on near-wellbore properties remains challenging.
View Article and Find Full Text PDFActa Psychol (Amst)
December 2024
University of Oslo, Norway. Electronic address:
How individuals process and understand controversial scientific issues with social implications has been linked to their beliefs about epistemic justification, which concern how knowledge claims can be justified. In this study, we used cluster analysis to classify undergraduate and graduate students (n = 46) based on their beliefs about epistemic justification and eye tracking to investigate how profiles of epistemic justification differed when processing and representing information about a particular socio-scientific issue. It was found that one cluster predominantly relied on justification by multiple sources, whereas two other clusters combined reliance on justification by multiple sources with either reliance on personal justification or justification by authority.
View Article and Find Full Text PDFFront Oncol
December 2024
Department of Neurosurgery, Oslo University Hospital, Oslo, Norway.
Background: The identification of modifiable risk factors for intracranial glioma remains a significant challenge. While lifestyle factors and metabolic syndrome are well-established risk factors for various other cancers, their association with glioma risk remains unclear.
Objectives: This study aims to conduct a comprehensive analysis of lifestyle factors and metabolic factors in relation to glioma risk.
Oncoimmunology
December 2025
Department of Cancer Immunology, Oslo University Hospital, Oslo, Norway.
The immune checkpoint inhibitor ipilimumab provides long term survival in some metastatic melanoma patients, but the majority has no benefit, and may experience serious side effects. Here, we investigated the dynamics of plasma cytokine concentrations and their potential utility for predicting treatment response, adverse events and overall survival (OS) in patients with metastatic melanoma undergoing ipilimumab monotherapy. A cohort of 148 patients was examined, with plasma samples collected prior to treatment initiation and at the end of the first and second treatment cycles.
View Article and Find Full Text PDFBasic Clin Pharmacol Toxicol
January 2025
Cancer Research Advocates Forum (CRAF-UK), Stevenage, UK.
In a 2022 consultation, the UK public highlighted the need to disseminate trial results to participants. We assess whether the information provided to trial participants in publicly available participant information sheets (PISs) of trials conducted in the UK is helpful for future trials. This cross-sectional study is based on a search conducted on 18 August 2023 on ClinicalTrials.
View Article and Find Full Text PDFMed Health Care Philos
December 2024
The Centre for Philosophy and the Sciences (CPS), Department of Philosophy, Classics, History of Art and Ideas, University of Oslo, Oslo, Norway.
Nat Comput Sci
December 2024
Department of Pharmacology, University of California San Diego School of Medicine, La Jolla, CA, USA.
Biological cells rely on precise spatiotemporal coordination of biochemical reactions to control their functions. Such cell signaling networks have been a common focus for mathematical models, but they remain challenging to simulate, particularly in realistic cell geometries. Here we present Spatial Modeling Algorithms for Reactions and Transport (SMART), a software package that takes in high-level user specifications about cell signaling networks and then assembles and solves the associated mathematical systems.
View Article and Find Full Text PDFDrugs R D
December 2024
Center for Thrombosis and Hemorrhagic Diseases, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy.