97 results match your criteria: "University of Oran 1[Affiliation]"

This study investigates the synthesis of corn starch nanocrystals (SNCs) via sulfuric acid hydrolysis. Esterification of oleic acid (OA) with SNCs was carried out using Maghnite-H as a catalyst, a non-polluting, eco-friendly proton-exchanged montmorillonite-based green catalyst suitable for various chemical processes. Optimization of synthesis parameters, including reaction temperature, duration, and catalyst quantity, was conducted using response surface methodology (RSM) with a central composite design incorporating three factors and three levels.

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Metal contamination of foodstuffs is a major public health challenge of increasing concern. The present study aimed to determine lead, cadmium and mercury in honey, cow's milk and poultry eggs collected from the North-Eastern region of Algeria and to evaluate the health risks associated with their regular consumption. To this aim 30 samples of each foodstuff were analysed using ICP-MS.

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Article Synopsis
  • Acute coronary syndrome (ACS) continues to be a major health challenge globally, even with improved treatment options.
  • This study evaluated the impact of empagliflozin, an SGLT2 inhibitor typically used for managing type 2 diabetes, on heart function in ACS patients by analyzing data from four randomized controlled trials with a total of 701 participants.
  • Results showed that empagliflozin significantly improved certain left cardiac parameters, like reducing left ventricular end-systolic volume and mass, although it did not significantly change left ventricular ejection fraction or end-diastolic volume, indicating its potential as a complementary treatment in ACS cases.
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This study evaluated the reliability of the emulsified liquid membrane (ELM) extraction technique for recovering and separating metals, focusing on Nickel (Ni(II)) and Samarium (Sm(III)), both used in electrochemical devices. Key contributions include determining optimal conditions for creating a stable water-in-oil (W/O) emulsion. The optimal conditions were found to be a 5-minute emulsification time, 4 wt.

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Background & Objectives: Rigid ring and Flexible band are techniques used to repair tricuspid valve regurgitation. The comparison between both techniques' effectiveness is controversial in the literature. We conducted this systematic review and meta-analysis to compare the safety and efficacy of rigid ring versus flexible band for tricuspid valve repair in patients with tricuspid valve regurgitation.

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Co expression of EGFR and CD10 in patients with phyllodes tumors of the breast: a single center experience in North Western Algeria.

Afr Health Sci

December 2023

Biology of Development and Differentiation Laboratory, Oran 1 University, Ahmed Ben Bella, Department of Biology, Faculty of Nature and Life sciences.

Background: Breast phyllodes tumors (BPT) have variable malignant potential, their histological classification remains insufficient for an accurate diagnosis.

Objectives: We attempted to investigate CD10 (Cluster of differentiation 10) and EGFR (Epidermal growth factor receptor) expression in BPT in order to highlight their diagnostic and prognostic values.

Methods: Eight patients with BPT are recruited from January 2014 to December 2020 and immunohistochemical assessment of CD10 and EGFR is realized.

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Purpose: The role of sodium-glucose cotransporter 2 inhibitors (SGLT2i) in managing cardiovascular outcomes in patients with type 2 diabetes mellitus (T2DM) is evolving. This meta-analysis seeks to explore the influence of SGLT2i on the recurrence of atrial fibrillation (AF) following catheter ablation (CA) in individuals with T2DM qualitatively and quantitatively.

Methods: A comprehensive literature search was conducted in electronic databases.

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Introduction: Pharmacogenetic markers, such as the ATP Binding Cassette (ABCB1) and cytochrome P450 (CYP) 3A5 enzymes, play a crucial role in personalized medicine by influencing drug efficacy and toxicity based on individuals' or populations' genetic variations.This study aims to investigate the genetic polymorphisms of CYP3A5 (rs776746) and ABCB1 (rs1045642) in the West Algerian population and compare the genotypes and allelic distributions with those of various ethnic groups.

Methods: The study involved 472 unrelated healthy subjects from the Western Algerian population.

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Biocompatibility of nano/micro-sized pyrophyllite particles by pulmo, liver, kidney and gastric mucosis cells.

J Mater Sci Mater Med

June 2024

University of Banja Luka, Faculty of Natural Sciences and Mathematics, Mladena Stojanovića 2, 78000, Banja Luka, Bosnia and Herzegovina.

Pyrophyllite is the least studied natural clay in terms of its potential in biomedical applications, although there are many deposits of this aluminosilicate around the world. Genotoxicity study was performed in vitro for this mineral. Subsequently, Wister rats were exposed to the pyrophyllite micronized to below 100 µm.

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Microribonucleic acids (miRNAs) have emerged as a new category of biomarkers for many human diseases like cancer, cardiovascular and neurodegenerative disorders. MicroRNAs can be detected in various body fluids including blood, urine and cerebrospinal fluid. However, the literature contains conflicting results for circulating miRNAs, which is the main barrier to using miRNAs as non-invasive biomarkers.

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Histopathological Study of Breast Cancer at the Oran University Hospital Center on a Population from Western Algeria.

Gulf J Oncolog

May 2024

Laboratory of Biology of Development and Differentiation, Faculty of Nature and Life Sciences, University of Oran 1 Ahmed Ben Bella, BP 16, Oran, Algeria.

Unlabelled: Breast cancer (BC) is the most common cancer among women worldwide and also in Algeria. Despite therapeutic progress, it remains a cancer with serious physical and psychological consequences.

Materials And Methods: The objective of this study was to perform a histological analysis on 244 patients from the western Algerian population who were receiving treatment at the Oran University Hospital.

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Article Synopsis
  • Rett syndrome is a rare neurodevelopmental disorder primarily affecting females, caused by mutations in the MECP2 gene on the X chromosome.
  • Trofinetide is a newly developed drug aimed at providing neuroprotective effects, and this meta-analysis assesses its efficacy and safety compared to placebo in treating RTT.
  • The results from three randomized controlled trials involving 325 patients indicate that Trofinetide significantly improves symptoms without severe side effects, making it a promising treatment option for RTT.
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Patients with heart failure (HF) and iron deficiency are at increased risk of adverse clinical outcomes. We searched databases for randomised controlled trials that compared IV iron to placebo, in patients with HF with reduced ejection fraction (HFrEF). A total of 7,813 participants, all having HFrEF with 3,998 receiving IV iron therapy, and 3,815 control recipients were included.

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Background: Despite advancements in the management of HIV infection, the factors contributing to stroke development among HIV-positive individuals remain unclear. This systematic review and meta-analysis aim to identify and evaluate the relative risk factors associated with stroke susceptibility in the HIV population.

Methods: A comprehensive search was conducted in PubMed, Scopus, and Web of Science databases to identify studies investigating the risk of stroke development in HIV patients and assessing the role of different risk factors, including hypertension, diabetes, dyslipidemia, smoking, sex, and race.

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Analysis of Bioactive Aroma Compounds in Essential Oils from Algerian Plants: Implications for Potential Antioxidant Applications.

Foods

February 2024

Departmento de Química Analítica, Instituto de Investigación en Ingeniería de Aragón (I3A), Escuela de Ingeniería y Arquitectura (EINA), Universidad de Zaragoza, María de Luna 3 (Edificio Torres Quevedo), 50018 Zaragoza, Spain.

In samples of (AC), (AHA) and (SJ) essential oils, up to 200 distinct volatile compounds were identified. Using headspace solid-phase microextraction combined with gas chromatography-olfactometry-mass spectrometry (HS-SPME-GC-O-MS), different panelists detected 52 of these compounds. This study offers the most detailed analysis of bioactive compound profiles conducted so far.

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Sleep paralysis (SP) is a mixed state of consciousness and sleep, combining features of rapid eye movement (REM) sleep with those of wakefulness. The exact cause of SP is unknown, and its prevalence varies among the studies. We aim to identify SP's global prevalence, the affected population's characteristics, and the SP's clinical picture.

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An Innovative Smart and Sustainable Low-Cost Irrigation System for Anomaly Detection Using Deep Learning.

Sensors (Basel)

February 2024

Laboratory of Parallel, Embedded Architectures and Intensive Computing (LAPECI), University of Oran 1, B.P. 1524, El M'Naouer, Oran 31000, Algeria.

The agricultural sector faces several difficulties today in ensuring the safety of food supply, including water scarcity. This study presents the design and development of a low-cost and full-featured fog-IoT/AI system targeted towards smallholder farmer communities (SFCs). However, the smallholder community is hesitant to adopt technology-based solutions.

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Functional gastrointestinal (GI) disorders are recognized as a major public health concern worldwide. These disorders involve persistent digestive symptoms indicative of digestive tract dysfunction. A survey examining the utilisation of probiotics and medicinal plants as supplementary treatments was conducted on 160 patients with GI disorders at healthcare institutions in Saïda from March to April 2023 using questionnaires that had been previously adapted and tested for reliability with Cronbach's alpha test.

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HLA-B*58 and HLA-B*27 Play a Role in the Development of Acute Leukemia: A Case Control Study.

Asian Pac J Cancer Prev

January 2024

Laboratory of Developmental Biology and Differentiation, BP 1510 El M’Naouer, Oran 1 Ahmed Ben Bella University, 31000, Oran, Algeria.

Background: Acute leukemia (AL) constitutes a group of malignant hematological diseases with multifactor origins. Some human leukocyte alleles (HLA) may be important genetic risk factors for development of acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL). It is still unknown whether there is a relationship between ALL and AML with some alleles of the major histocompatibility complex.

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Objectives: To investigate dual-energy computed tomography's (DECT) diagnostic performance in detecting neurological complications following endovascular therapy (EVT) of acute ischaemic stroke (AIS).

Methods: We performed the literature search using Web of Science, Scopus, PubMed, EBSCO, and Science Direct databases for published related studies. The selected studies estimated the validity of DECT in the detection of neurological complications after EVT for AIS.

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Allele and genotype frequencies of β-lactoglobulin gene using PCR-RFLP in Algerian local cattle populations.

Mol Biol Res Commun

January 2024

Laboratory Genetics Molecular and Cellular, Department of Molecular Genetics Applied, Faculty of Nature and Life Sciences, University of Science and Technology of Oran "Mohamed Boudiaf ", B.P 1505 El M'Naouar, 31000 Oran, Algeria.

Milk protein genetic polymorphisms are associated with economically important traits in dairy cattle. The objective of this study is to genotype a single nucleotide polymorphism (SNP) responsible for the amino acid changes in the beta-lactoglobulin (β-Lg) variants A and B on 85 unrelated DNA representing Algerian cattle populations: Chelifienne (28), Cheurfa (31) and Guelmoise (26). The method used is the PCR-RFLP (Polymerase Chain Reaction-Restriction Fragment Length Polymorphism).

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Background: The global COVID-19 pandemic has deeply impacted health systems, emphasizing the need for effective vaccination campaigns. However, vaccine hesitancy, particularly among healthcare workers, challenges achieving comprehensive immunization coverage. The primary objective of this study is to elucidate the factors influencing COVID-19 vaccine uptake among healthcare workers at an Algerian University Teaching Hospital.

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Metallic trace element dynamics in Paracentrotus lividus from Algeria: Environmental large-scale survey and human health risk assessment.

Sci Total Environ

March 2024

SciSca SRL, 5330 Maillen, Belgium; Station de Recherches Sous-marines et Océanographiques, Punta Revellata, BP33, 20260 Calvi, France.

This paper evaluates the dynamics of Metallic Trace Elements (MTEs; Cd, Pb, Fe, Cu, Zn, Ni and Co) in the gonads of the sea urchin Paracentrotus lividus collected in five sites: four contaminated and one reference, along the Western coast of Algeria, recontextualizes this contamination within a wider geographical distribution area throughout 83 sites among the Mediterranean Sea and Atlantic and focuses on the potential risk of their consumption on human health for the first time in Algeria. The trace element pollution index places Algeria, and generally the North African coasts, as the region most contaminated by MTEs. The geographical variability in metal contamination levels is greater in the Mediterranean Sea than in the Atlantic.

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The objective of this investigation is to assess the efficacy of ropivacaine on intraoperative and postoperative endpoints like operative time, blood loss, pain, and bleeding among adult's patients undergoing for tonsillectomy. PubMed, CENTRAL, Scopus, and Web of Science databases were screened from inception until November 2022. The included RCTs were evaluated for risk of bias via risk of bias tool (second version).

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